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Blog About Legit HGH Supplement Chosen by Athletes :: Luke … – SportsBlog.com (blog)

Feb 22nd, 2017
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Luke Willmott, an amateur rugby union player saw his anti-doping ban doubled to four years by the Court of Arbitration for Sport. He was tried for importing large quantity of human growth hormone in 2013.

The Nottingham-based player came under scanner when authorities seized a parcel containing 180 vials of Jintropin, a performance enhancing and body-building hormone drug, which was addressed to him. On examination it was found that the substance was not human growth hormone (HGH) but that does not brought any relief for Willmontt.

In 2014, a year after the incidence, the former Derby RFC captain was interviewed by the UK Anti-Doping and later in July same year was charged by the Rugby Football Union for attempting to traffic and attempting to use a banned substance.

Willmott was initially given a 5 year ban by the RFU anti-doping panel in April 2015. Later on in January 2016 an RFU appeal panel reduced his ban to two years.

However the decision was not accepted as wise by the sport bodies worldwide and World Anti-Doping Agency along with World Rugby took the decision to the highest sports court, CAS. Hearing on the case the Swiss-based panel set the ban to four years for Willmott.

The amateur rugby player is also banned from participating in all competitive sport until August 15, 2017.

Authorities are trying their best to control doping in sports. Ensuring the same Stephen Watkins, RFU anti-doping program manager, quoted in a press release-“Trafficking is a very serious offence under the world anti-doping code.

“As a union, we advocated for a ban of at least four years and support the increase from the decision of the RFU anti-doping appeal panel. Players should be aware that all doping offences will be treated seriously, irrespective of what level you play at.”

Nicole Sapstead, UKAD chief executive, share the same opinion. According to him, “substances such as human growth hormone and steroids continue to pose a real and significant threat to both clean sport and to the health of our young people.

“Trafficking is a serious offence and, alongside our partners, we will look to impose the maximum sanction on individuals who choose to break the rules.

“Identifying and targeting the supply of serious substances, such as steroids and human growth hormone, is a critical part of preventing the growing problem of image and performance enhancing drugs.

“I encourage anyone with information or concerns about doping to talk to us in confidence via reportdoping.com.”

Willmotts case update came out almost the same time around when RFUs annual anti-doping report is released and reveals that although RFU is doing record number of tests in the Aviva Premiership but they are not enough to test every player.

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Versartis Reports Fourth Quarter 2016 Financial Results – P&T Community

Feb 22nd, 2017
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Versartis Reports Fourth Quarter 2016 Financial Results
P&T Community
21, 2017 (GLOBE NEWSWIRE) — Versartis, Inc. (NASDAQ:VSAR), an endocrine-focused biopharmaceutical company that is developing somavaratan, a novel, long-acting form of recombinant human growth hormone (rhGH) for growth hormone deficiency …
Versartis Inc. (VSAR) Moves Higher on Volume Spike for February …Equities.com
Versartis Inc (VSAR) Releases Earnings Results, Beats Expectations By $0.21 EPSMoney Flow Index & Trends

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Does Testosterone Improve Older Men’s Health? It Depends – NPR

Feb 22nd, 2017
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Several new studies show mixed results for men taking testosterone supplements. Garo/Phanie/Passage/Getty Images hide caption

Several new studies show mixed results for men taking testosterone supplements.

Many men over 65 with low testosterone levels say their sense of well-being, not to mention sexual function, isn’t what it used to be.

That’s why some doctors prescribe testosterone replacement. But the effectiveness of testosterone has been controversial. Studies of the risks and benefits have been mixed, and the Food and Drug Administration beefed up its warnings about cardiac side effects of testosterone supplementation in 2015.

And the findings of five studies released Tuesday aren’t likely to clear up the confusion. They appear in JAMA, the journal of the American Medical Association and JAMA Internal Medicine.

The studies are collectively called the Testosterone Trials (TTrials) and they compared a testosterone gel, AndroGel, against a placebo. The results are based on 788 men with below normal levels of testosterone studied at 12 sites across the country over a year.

Overall, researchers saw improvements in bone density and bone strength in men who used a testosterone gel, which raised their testosterone to levels seen in younger men.

In men with unexplained anemia, testosterone also improved iron levels in the blood. (A reviewer of the study raised questions about whether it was done ethically.)

But in men using testosterone who had been reporting memory problems at the start of the study, there were no improvements in memory or cognition. And there were worrisome signs of an increase in the risk of cardiovascular problems.

Taken together, says Dr. David Handelsman of the University of Sydney and Concord Hospital in Australia, the TTrials “do not materially change the unfavorable balance of safety and efficacy to initiate testosterone treatment.” His comments appear in an editorial in JAMA.

“Low testosterone levels due to obesity” and other aging health problems, Handelsman says, “are better addressed by lifestyle measures” directed at those problems. He also called for strengthened warnings on the drug’s packaging to note the cardiovascular risk.

In another accompanying editorial, Eric Orwoll, a professor of medicine at the Oregon Health and Science University, says convincing answers about the effects on cardiovascular health remain “elusive” and will require large, prospective randomized trials.

“At this point, clinicians and their patients should remain aware that the cardiovascular risks and benefits of testosterone replacement … have not been adequately resolved,” he says.

The results

The red flag on cardiovascular risk was raised in the TTrials’ Cardiovascular Trial, where researchers found an increase in plaque buildup, a known risk factor for heart disease. The study was based on 73 men using the gel and 65 receiving a placebo. The study was originally done because there had been suggestions that testosterone has heart benefits.

Indeed, another trial published Tuesday, which was not part of the TTrials, showed a lower risk of cardiovascular events, including heart attack or stroke, in men who’d received testosterone, on average, for 3.4 years.

Somewhat more positive results were seen in the TTrials’ Bone Trial. Among men using the testosterone gel, there were statistically significant improvements in lumbar spine and hip bone density and bone strength. There was a small and equivalent number of bone fractures in each group. The Bone Trial included 189 of the 790 men in the overall study.

But another TTrial, the Cognitive Function Trial, failed to find improvements in memory and cognitive skills associated with testosterone treatment. This trial studied 493 men who had age-associated memory impairment at the start of the study, as measured by subjective memory complaints and objective memory performance.

The TTrials started out by screening more than 51,000 men 65 and older. To qualify for one of the subtrials, men needed a blood level of testosterone to be below 275 ng/dL, just below the range many doctors consider “normal” for healthy, younger men.

After screening, 788 men were considered to have low testosterone.

Until the first year of TTrials was over, neither the participants nor the researchers knew which men were getting the placebo or the testosterone gel.

The first set of TTrial studies was reported last year in the New England Journal of Medicine. Those looked at sexual function, physical activity and mood and found that sexual function and desire did improve significantly among men using the testosterone gel.

Some mood improvements were also noted although there was not significant improvement in overall vitality or in physical activity.

Final decisions about testosterone treatment for older men will depend on “balancing the results” from the TTrials “with the results from a much larger and longer-term trial designed to assess cardiovascular and prostate risk,” says endocrinologist Peter Snyder of the University of Pennsylvania, who headed the studies.

In the meantime, TTrial researcher Susan Ellenberg says decisions about whether to take or not take testosterone should be made between older men and their physicians, taking into account overall health and medical history while weighing potential benefits and risks.

The studies were funded by the National Institute on Aging and other parts of the National Institutes of Health. Additional funding was provided by the maker of AndroGel, AbbVie, which also supplied the drug, which is customary in clinical trials. The company was not otherwise involved in the implementation or analysis of the trial.

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Testosterone treatment improves bone density and anemia, may lead to cardiac risk – Science Daily

Feb 22nd, 2017
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Testosterone treatment improves bone density and anemia, may lead to cardiac risk
Science Daily
It is commonly known that testosterone levels decrease as men age, but until last year, little was known about the effects of testosterone treatment in older men with low testosterone. Today, in a group of papers published in the Journal of the

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Testosterone gel shows no benefit for older men’s memories – Midland Reporter-Telegram

Feb 22nd, 2017
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Lindsey Tanner, Ap Medical Writer

Photo: Richard M. Hackett, AP

Testosterone gel shows no benefit for older men’s memories

CHICAGO (AP) Testosterone treatment did not improve older men’s memory or mental function in the latest results from landmark government research that challenges the anti-aging claims of popular supplements.

While testosterone use for one year appeared to strengthen bones and reduce anemia, it also showed signs of worsening artery disease and questions remain about other potential risks. The researchers said more studies are needed to determine long-term effects the kind of research the U.S. Food and Drug Administration has already asked supplement makers to conduct.

“I don’t think anybody would interpret these results as saying, ‘Wow, this is a fountain of youth, this is a magical anti-aging potion,'” said study co-author Susan Ellenberg, a University of Pennsylvania researcher.

The results are from the final four studies in a seven-part project mostly funded by the National Institute on Aging, involving nearly 800 U.S. men aged 65 and older with low testosterone levels. The goal was to see if rubbing testosterone gel on the skin daily for a year could treat problems linked with low levels of the male hormone, which declines with age. Half the men in each group used the real thing and half used fake gel.

Results published a year ago from the same research linked testosterone with mostly modest improvement in sexual performance, walking strength and mood.

The key new findings:

Testosterone had no effect on memory or mental function, based on tests given before, halfway and at the end of treatment to nearly 500 men with age-related memory decline.

Among almost 140 men who underwent heart artery imaging tests to see if the hormone slowed progression of plaque, those who used testosterone had more plaque buildup and narrower arteries after a year than the fake gel group. Those changes could signal increased chances for heart attacks although none occurred in the study. Men in this sub-study were already more vulnerable for heart problems because of conditions including artery disease, obesity and high blood pressure.

Among about 200 men given bone imaging tests before and at the end of treatment, those on testosterone showed increases in bone density and strength, especially in the spine, while minimal changes were found in the group that used fake gel. The improvement was similar to bone changes seen with treatment for osteoporosis, although most men studied did not have that bone-thinning condition, which can lead to fractures.

Among 126 men with anemia, a fatigue-linked condition involving inadequate red blood cells, those on testosterone showed substantial improvement. By the study’s end, anemia had vanished in almost 60 percent of men on testosterone compared with 22 percent of the fake gel group. The hormone group also reported having more energy. “The overall health benefits, however, remain to be determined,” the researchers said.

The studies were published Tuesday in the Journal of the American Medical Association and JAMA Internal Medicine. AbbVie Pharmaceuticals provided its gel for the study and helped pay for the research but had no other role in the study.

The research was not designed to look at risks and does not apply to younger men or those with normal levels of testosterone, said study leader Dr. Peter Snyder, a University of Pennsylvania hormone specialist. It’s also not known if other forms of testosterone supplements would have similar effects in older men with low levels.

Prescription testosterone products including gel are approved only for men with low levels of the hormones caused by various medical conditions. Benefits and risks are unknown in men whose levels are low due only to aging, the FDA says. The agency requires testosterone labels to include possible risks for heart attacks and strokes, based on some previous studies.

A separate study published Tuesday in JAMA Internal Medicine found that men using prescription testosterone gel, patches or injections had fewer heart attacks and strokes during about three years of follow-up than non-users. But this was only observational data in men aged 40 and up, not rigorous research testing the hormone against a placebo.

Clarifying testosterone’s effects on heart problems, fractures and age-related disability will require larger, longer studies, said Dr. Evan Hadley of the National Institute on Aging. He said decisions about whether to use testosterone should take into account men’s individual risks for conditions the hormone could affect.

___

Online:

National Institute on Aging: http://www.nia.nih.gov

___

Follow AP Medical Writer Lindsey Tanner at http://www.twitter.com/LindseyTanner. Her work can be found at http://bigstory.ap.org/content/lindsey-tanner

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NIH-Supported Trials of Testosterone Therapy in Older Men Report Mixed Results – eNews Park Forest

Feb 22nd, 2017
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Hormone treatment improved bone strength and hemoglobin levels; may increase cardiovascular risk; had no effect on cognition.

Bethesda, Maryland(ENEWSPF)February 21, 2017. In older men with low testosterone, one year of testosterone treatment improved bone density and corrected anemia of both known and unknown causes, but also increased the volume of coronary artery plaque, according to results reported from the Testosterone Trials (T Trials). Testosterone treatment had no effect on memory or other cognitive function. The results are reported in two journals coming out this week.

The T Trials were conducted at 12 sites across the country in 790 men age 65 and older with low levels of testosterone and symptoms to which low testosterone might contribute. The studies were funded primarily by the National Institute on Aging (NIA), part of the National Institutes of Health. Additional funding came from the National Heart, Lung, and Blood Institute, the National Institute of Neurological Disorders and Stroke, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, all part of NIH. Additional funding, and the study drug and placebo, were provided by AbbVie Pharmaceuticals.

A number of older men have testosterone levels below those found in healthy younger men, said NIA Director Richard J. Hodes. M.D. In most cases, these low levels are not due to diseases known to affect testosterone levels. Many of these men also have problems that could be related to low testosterone, including impaired cognition, anemia, cardiovascular disease, diminished sexual function, decreased mobility and fatigue. The T Trials were designed to determine if testosterone treatment might help alleviate these symptoms and conditions while monitoring for adverse effects.

The findings were reported in journals of the American Medical Association cited below, by principal investigator Peter J. Snyder, M.D., with the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, and colleagues at the 12 study sites.

Participants were randomly assigned to receive testosterone gel or a placebo gel applied to the skin daily. Serum testosterone concentration was measured at one, two, three, six, nine and 12 months. The men were also closely monitored for prostate and cardiovascular problems. In addition to low testosterone, the presence of complaints such as low sexual function, difficulty in walking or low vitality was required for eligibility to participate in the trials. The results of these outcomes were reported in 2016.

The study also measured testosterone treatments effects on additional outcomes in the study population, which are reported in the current publications: Effects on anemia and bone density appear on February 21 issue in JAMA Internal Medicine. The results of the cardiovascular and cognitive function trials will also appear on February 21 in the Journal of the American Medical Association.

The results on diverse outcomes indicate the potential trade-offs between benefits and risks of testosterone treatment in older men, said Evan Hadley, M.D., director of NIAs Division of Geriatrics and Clinical Gerontology. However, clarifying the effects of testosterone on many major clinical outcomes such as cardiovascular events, fractures, and disability will require longer, larger scale trials. The results also illustrate that decisions about testosterone treatment need to be individualized, taking into account each patients balance of risks for the various conditions that testosterone treatment could affect.

The U.S. Food and Drug Administration has additional information about testosterone (link is external).

About the National Institute on Aging (NIA): The NIA leads the federal government effort conducting and supporting research on aging and the health and well-being of older people. The Institutes broad scientific program seeks to understand the nature of aging and to extend the healthy, active years of life. For more information on research, aging, and health, go to http://www.nia.nih.gov.

About the National Institutes of Health (NIH): NIH, the nations medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

Source: http://nih.gov

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Testosterone has no benefit for older men’s memories: Study – Tri-City Herald

Feb 22nd, 2017
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Testosterone has no benefit for older men's memories: Study
Tri-City Herald
Testosterone treatment did not improve older men's memory or mental function in the latest results from landmark government research. The results add to evidence that challenges bold anti-aging claims of popular supplements. While testosterone use for

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Likelihood of dieting success lies within your tweets – Phys.org – Phys.Org

Feb 22nd, 2017
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February 21, 2017 by Ben Snedeker Credit: Georgia Institute of Technology

There is a direct link between a person’s attitude on social media and the likelihood that their dieting efforts will succeed.

In fact, Georgia Institute of Technology researchers have determined that dieting successor failurecan be predicted with an accuracy rate of 77 percent based on the sentiment of the words and phrases one uses on Twitter.

“We see that those who are more successful at sticking to their daily dieting goals express more positive sentiments and have a greater sense of achievement in their social interactions,” said Assistant Professor Munmun De Choudhury, who is lead researcher on the project. “They are focused on the future, generally more social and have larger social networks.”

Words and phrases like “Train smart like a trainer… win like 6 time champion [sic],” “If your not failing your not trying hard enough… [sic],” and “If we never stumble we never fall. If we never fall we never fail, and if we never fail we never grow!” are some examples of the upbeat and self-reflective language the research indicates is most common to successful dieters.

Other traits of successful dieters are that they tend to be more focused on topics related to health and fitness, and they are more socially interactive.

“We see that these users are much more likely to share healthy recipes, offer tips on nutrition and exercise, and report on their own progress,” said De Choudhury. “Their larger network of friends and followers, and increased engagement, means that they tend to also have stronger support systems, which positively impacts the likelihood of dieting compliance.”

As for those who are not successful in meeting dietary goals, their Twitter content often has a demonstrably negative tone and they tend to be more uneasy and fearful in their posts.

“These users tend to be more anxious seemingly because of a lack of emotional control, and because of certain activities and events of daily life,” said De Choudhury.

Sample posts here include, “I’m pretty sure I’m going to lose my mind. Completely lose what little is left. I cry at the thought of stupid things…” and “Feel rough as old boots this morning :/ Ankle hurts, shin hurts, chest hurts, head hurts.”

While the study of Twitter in isolation can reveal insights into users’ health status, this research breaks new ground in that the study group consists of individuals who have connected their MyFitnessPal (MFP) – a calorie-counting app – and Twitter accounts.

“These areas have been individually observed to glean health indicators,” explained De Choudhury. “However, considering these data sources together and applying an established causality testing methodology allows us to validate for the very first time the efficacy of social media and quantified self-sensing in revealing risk to diet compliance.”

The research looks at more than 2 million tweets and 100,000+ daily MFP entries from nearly 700 individuals. Twitter’s official streaming API was used to identify qualified users by searching publicly shared posts with the hashtag “#myfitnesspal” and that contained an embedded link.

An individual’s MFP food diary entries were coupled with Twitter posts from the corresponding time period. From this, adherence to their set dieting goals was compared to attitudes and behaviors expressed in the tweets.

Tweets were analyzed for linguistic attributes that reveal connections between a person’s behavioral expression and their health and wellbeing. Along with affective and cognitive aspects, the linguistic style of the tweets was also examined.

In future, De Choudhury suggested the new analytical method could be pushed forward to provide greater health and wellbeing benefits.

“For instance, by temporally aligning social media, quantified self sensing and self-reported attributes, statistical models may be able to explore dynamics of events around when or how soon an individual’s diet is likely to fail,” said De Choudhury. “This would allow for proactive measures to be taken to help ensure more positive health outcomes.”

A paper titled Computational Approaches Toward Integrating Quantified Self Sensing and Social Media details these findings and is being presented later this month at the 20th ACM Conference on Computer-Supported Cooperative Work and Social Computing.

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There is a direct link between a person’s attitude on social media and the likelihood that their dieting efforts will succeed.

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Tired of the Ups and Downs of Yo-Yo Dieting? – WebMD

Feb 22nd, 2017
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By Dennis Thompson

HealthDay Reporter

MONDAY, Feb. 20, 2017 (HealthDay News) — Anyone who has been on a diet knows the real challenge comes later, when you’ve got to fight tooth and nail to keep from regaining the lost weight.

Now, a new trial finds that regular “diet coaching” may help keep the weight off.

People were more likely to maintain successful weight loss if they took part in a series of post-diet coaching sessions conducted mostly by phone, said study author Corrine Voils. She is scientific director of the Wisconsin Surgical Outcomes Research Program at the University of Wisconsin.

Dieters who received coaching had only regained about a pound and half, on average, a year after their initial weight loss, Voils said. Successful dieters who received no follow-up coaching regained about 5 pounds.

Typically, most people tend to regain weight at a rate of about 2 to 4 pounds a year, the study authors said in background notes.

“The program did slow the rate of regain over that period,” Voils said.

Previous research has shown that people who are taught specific behavioral skills can better maintain weight loss, Voils said.

For this study, Voils and her colleagues combined several of those skills and regularly reinforced them with successful dieters during a 42-week period.

The participants were 222 patients at VA clinics in North Carolina who lost an average of 16 pounds as part of a structured weight-loss program.

Following their weight loss, these folks were randomly assigned to receive regular coaching from dietitians or were left to their own devices.

The coaching included a few group visits at first, but quickly transitioned into regular phone calls, Voils said.

“We started out with biweekly contacts, and then decreased to monthly and then to every two months,” she said.

The coaching hit on four major themes for weight-loss maintenance, Voils said.

The first involved weighing oneself regularly to identify any sudden weight gain. Patients were told to react if they noticed that they’d put back on 3 pounds.

“Once you regain 3 pounds, this means that you’re on a trajectory to regain weight. You need to go back to your weight-loss effort,” Voils said. “It’s easier to recuperate from a small slip than it is from a 20-pound slip.”

Participants also were encouraged to:

Many weight-loss programs feature one or more of these strategies, but they are rarely combined and usually are emphasized during the initial weight-loss period, not as a part of long-term maintenance, Voils said.

After 42 weeks, patients were left alone for 14 weeks and then weighed again to see whether they’d experienced any weight gain.

Voils said the program was low-cost — about $276 per participant for 56 weeks — which makes it a fairly inexpensive way to help people stay healthy and fit following a weight-loss program.

“There could be a distinct phase after initial weight loss where this could benefit,” Voils said. “There’s accountability by somebody calling you regularly.”

Dr. Donald Hensrud, editor of “The Mayo Clinic Diet,” said the study “demonstrates that some follow-up in this period through telephone calls could be beneficial.”

Hensrud also directs the Mayo Clinic Healthy Living Program, a wellness program that offers six months to a year of follow-up from coaches.

“We haven’t done a research study like this, but we designed it [the program] for similar reasons,” Hensrud said. “We think that staying in touch with people during this so-called maintenance phase is important. People respond to it.”

Voils couldn’t say whether people who’ve lost weight would require such coaching for the rest of their lives, to prevent regaining those pounds.

“I would love to do that next study to figure that out,” she said.

The study was funded by the U.S. Department of Veterans Affairs, and the results were published Feb. 21 in the Annals of Internal Medicine.

WebMD News from HealthDay

SOURCES: Corrine Voils, Ph.D., scientific director, Wisconsin Surgical Outcomes Research Program, University of Wisconsin School of Medicine and Public Health, Madison; Donald Hensrud, M.D., editor, “The Mayo Clinic Diet,” and director, Mayo Clinic Healthy Living Program, Rochester, Minn.; Feb. 21, 2017, Annals of Internal Medicine

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Yo-yo dieting ‘is good for you’ – and much better than not dieting at … – Mirror.co.uk

Feb 22nd, 2017
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Yo-Yo dieting might not be such a bad thing after all, experts have said.

Previous studies found that people who go through an endless cycle of losing weight then piling it back on could be harming their health.

But a leading researcher in the US has found evidence suggesting yo-yo dieting is better than not dieting at all.

Dr David Allison said: What we found is that when we make mice who are obese keep on repeatedly losing and gaining that weight, they live longer than the mice that are allowed to stay obese.

So we think its probably not a bad idea to lose weight even if you gain it back and redo it every few years.

The senior scientist at the University of Alabama Nutrition Obesity Research Center said the recent study on mice has not yet been published.

Dr Allison was speaking at the annual meeting of the American Association for the Advancement of Science in Boston, Massachusetts.

Professor Susan Jebb, a nutrition scientist at the University of Oxford, backed Dr Allisons comments.

She said: I agree with the notion that losing weight is generally worthwhile, even if you put the weight back on.

We have good evidence from long-term follow-up studies after controlled intervention studies in humans that there is a benefit.

Describing a study into yo-yo dieting, she said one group lost around a stone and gradually regained it over four years. These people reduced their risk of diabetes by 58% compared to a control group who lost little or no weight.

She said the risk was still 27% less when the weight of the two groups had been about the same for a decade.

But Professor Timothy Spector, a genetics expert at Kings College London and author of The Diet Myth, said yo-yo dieting should be avoided at all costs.

He added: Data in humans shows yo-yo dieting makes you gain weight long term.

In our study of 5,000 twins the yo-yo dieter was usually heavier long term than the identical twin who didnt diet.”

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