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Congenital GHD results from genetic error, and may be associated with brain structure defects or with midline facial defects such as a cleft palate or single central incisor.

Several genetic defects have been identified:

Growth hormone deficiency IA is autosomal recessive and is characterized by growth retardation in utero. Affected children are small in relation to their siblings. The infant usually has a normal response to administration of human growth hormone (hGH) at first, but then develops antibodies to the hormone and grows into a very short adult.

Growth Hormone Deficiency IB is also autosomal recessive and is similar to IA. However, there is some growth hormone (GH) present in the child at birth and usually the child continues to respond to hGH treatments.

Growth Hormone Deficiency IIB and III are similar to IB, but IIB is autosomal dominant and III is X-linked.

Classic genetic diseases are the product of the interaction of two genes, one received from the father and one from the mother.

Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary to cause a particular disease. The abnormal gene can be inherited from either parent or can be the result of a new mutation (gene change) in the affected individual. The risk of passing the abnormal gene from affected parent to offspring is 50% for each pregnancy. The risk is the same for males and females.

Recessive genetic disorders occur when an individual inherits two copies of an abnormal gene for the same trait, one from each parent. If an individual receives one normal gene and one gene for the disease, the person will be a carrier for the disease but usually will not show symptoms. The risk for two carrier parents to both pass the defective gene and have an affected child is 25% with each pregnancy. The risk to have a child who is a carrier like the parents is 50% with each pregnancy.

The chance for a child to receive normal genes from both parents and be genetically normal for that particular trait is 25%. The risk is the same for males and females.

Parents who are close relatives (consanguineous) have a higher chance than unrelated parents to both carry the same abnormal gene, which increases the risk of having children with a recessive genetic disorder.

X-linked genetic disorders are conditions caused by an abnormal gene on the X chromosome and manifest mostly in males. Females that have a defective gene present on one of their X chromosomes are carriers for that disorder. Carrier females usually do not display symptoms because females have two X chromosomes and only one carries the defective gene. Males have one X chromosome that is inherited from their mother and if a male inherits an X chromosome that contains a defective gene he will develop the disease.

Female carriers of an X-linked disorder have a 25% chance with each pregnancy to have a carrier daughter like themselves, a 25% chance to have a non-carrier daughter, a 25% chance to have a son affected with the disease and a 25% chance to have an unaffected son.

If a male with X-linked disorders is able to reproduce, he will pass the defective gene to all of his daughters who will be carriers. A male cannot pass an X-linked gene to his sons because males always pass their Y chromosome instead of their X chromosome to male offspring.

Acquired GHD can occur as a result of many different causes including brain trauma (perinatal or postnatal), central nervous system infection, tumors of the hypothalamus or pituitary (pituitary adenoma, craniopharyngioma, Rathkes cleft cyst, glioma, germinoma, metastases), radiation therapy, infiltrative diseases (Langerhans cell histiocytosis, sarcoidosis, tuberculosis), or, if without another diagnosis, it is considered idiopathic.

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Growth Hormone Deficiency - NORD (National Organization ...

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Mar 9th, 2019 | Filed under Human Growth Hormone

Muscle is the main building block of muscles. Protein is comprised of amino acids that the body can use. The strength of muscles depends on the availability of amino acids for the body. If the body cannot assimilate them, the muscles will begin to shrink and weaken.

Even if sufficient amounts of protein are ingested, the percentage of what can be utilized by the body varies depending on the bodys capability to use the amino acids. The growth hormone is responsible, besides all other things, for the utilization of amino acids by the body. This ensures that the muscles get their proper nourishment.

The clinical studies show that HGH impacts energy levels. Energy levels depend on the physical body as well as on the emotional and mental state. Growth hormone has statistically shown to improve the vitality that comes with physical, mental, and emotional energy. Fatigue can be treated with significant levels of HGH.

One of the benefits of HGH is the increased stamina and durability. Having a good stamina is having stable energy levels that do not change throughout the day or different activities. When one has good stamina they do not experience highs or lows in energy and do not need stimulants to keep them productive. HGH can boost both and make sure that it is constant energy throughout the day.

One of the most notorious HGH benefits for females that want to look good is the reduction of body fat. HGH boosts the metabolism rates to the ones that are experienced in early youth. This boost in HGH levels decreases fat on the abdomen, waist, thighs, and hips. At the same time, muscle mass is increased which creates a lean and fat-free body.

HGH benefits for males that are building-up their body are the ability to grow a lean body muscle mass. According to medical studies, the positive effects of HGH are seen on the effectiveness from exercising and gym sessions. People who use HGH are surprised at the fast and huge increase in muscle mass from HGH and the change of body composition in a short amount of time.

One of the major HGH benefits for adults even if they are not up for better looks is the improved sleep quality and efficiency. Because the bigger part of growth hormone secretion takes place at night when we sleep, sleep quality is directly connected to the secretion of growth hormone in the pituitary gland. The quality sleep that occurs after growth hormone increase relieves people who suffer from insomnia with a good sleep and lets them feel more energy throughout the day.

Of the HGH health benefits, an improved mood is one of them. Human growth hormone can act as a natural antidepressant. This is because human growth hormone increases the levels of endorphin within the brain. Endorphins are responsible for the good feeling that one has. HGH also lowers dopamine levels that give only a temporary sense of satisfaction and then leave one agitated. The improved sense of wellbeing, memory, and concentration also increase mood.

The immune system is directly connected to the quality and quantity of HGH release. There is a stronger immunity with the boost of HGH and benefits the entire body. The HGH boosts the T-cell and interleukin 2 production as well as the production of new antibodies. These are the primary factors in disease fighting. The lower risk of disease and inflammation improves the production of red blood cells and promotes better overall immunity to external threats.

Females can really appreciate the improved skin and hair quality with the intake of HGH. The HGH benefits for females go far beyond the youthfulness of appearance. The skin becomes more elastic and contours the face better. The deep wrinkles and small lines become less pronounced. Hair is also positively affected. People who take HGH have reported and seen new hair growing in its natural color. Because of the improved skin thickness, cellulite disappears and the nails become stronger.

HGH benefits for seniors include an improved memory. The hormone works to repair and rejuvenate brain cells. The memories in the brain are stored via protein production. This is also boosted with the increase of HGH. The process of learning and intelligence both require sufficient amounts of HGH produced by the body or supplemented.

As many know, antioxidants like the vitamins C and E are responsible for combating the damage done by free radicals. Many do not know of the benefits of HGH in the fighting of oxidative stress. HGH can directly affect proteases by activating cell defense systems known as protease inhibitors. This blocks the work of free radicals. This is a much more complex type of cell protection than antioxidants by themselves can provide.

The brain and nervous system are comprised of neurons. The human growth hormone can do something that was thought to be impossible to rejuvenate and repair neurons. This helps with cognitive function and overall performance of the entire nervous system which controls the entire body.

A powerful part of the HGH benefits for adults is the boost of sexual desire. Women report an increase in pleasure and men improved their sexual potency. The best of the HGH benefits for males is the improvement of erectile dysfunction. Females can benefit from ridding themselves of vaginal dryness, menstrual problems, and menopause symptoms.

What are HGH benefits for the skeletal system? Bone growth is at its peak during puberty when the body is growing. HGH stimulates the production of IGF-1 by the liver that is released in the blood and contributes to the growth and increase in bone density. This leads to a more bone mass as well. With the same process of bone growth, the HGH benefits the healing of broken and fractured bones at a faster and more efficient level.

HGH benefits for seniors can be seen with the improvement of cardiovascular function. This is because the lipoprotein metabolism is directly controlled by HGH levels.

The best ways to increase secretion of HGH naturally are:

The results of HGH and benefits that are achieved with its intake can be seen in a measurable timeline. The HGH health benefits are seen soon as the hormone acts fast. If the results are expected to be long lasting, however, one must be patient with the results. The HGH benefits timeline looks something like this.

During the first month, the mood and energy will be noticeably improved. The sleep quality improvement also comes within the first month.During the second month, the HGH will start regenerating the body and the quality of the hair and skin will change dramatically. Muscles will be more toned and the weight loss will be seen.

The third to fifth timeline mark will show an improvement in the physique with an increase in lean muscle mass. Memory and cognitive function will also rise.By the end of the sixth month, the HGH user will be back to ideal weight, achieve good muscle tone, and have sufficient energy levels. Improvements in cardiovascular and immune system function are also seen.

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Human Growth Hormone (HGH) Benefits for Men and Women

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Jan 21st, 2019 | Filed under Human Growth Hormone

Alternative names for growth hormone

Somatotropin; GH; human growth hormone; HGH

Growth hormone is released into the bloodstream from the anterior pituitary gland.The pituitary gland also produces other hormones that have different functions from growth hormone.

Growth hormone acts on many parts of the body to promote growth in children.Once the growth plates in the bones (epiphyses) have fused growth hormone does not increase height. In adults, it does not cause growth but it helps to maintain normal body structure and metabolism, including helping to keep blood glucose levels within set levels.

Growth hormone release is not continuous; it is released in a number of bursts or pulses every three to five hours.This release is controlled by two other hormones that are released from the hypothalamus (a part of the brain): growth hormone-releasing hormone, which stimulates the pituitary to release growth hormone, and somatostatin, which inhibits that release.

Growth hormone levels are increased by sleep, stress, exercise and low glucose levels in the blood. They also increase around the time of puberty. Growth hormone release is lowered in pregnancy and if the brain senses high levels of growth hormone or insulin-like growth factors already in the blood.

Not surprisingly, too much growth hormone causes too much growth.

In adults, excessive growth hormone for a long period of time produces a condition known as acromegaly, in which patients have swelling of the hands and feet and altered facial features. These patients also have organ enlargement and serious functional disorders such as high blood pressure, diabetes and heart disease.Over 99% of cases are due to benign tumours of the pituitary gland, which produce growth hormone.This condition is more common after middle-age when growth is complete so affected individuals do not get any taller.

Very rarely,increased growth hormone levels can occur in children before they reach their final height, whichcan lead to excessive growth of long bones, resulting in the child being abnormally tall. This is commonly known as gigantism (a very large increase in height).

Overproduction of growth hormone is diagnosed by giving a sugary drink and measuring the growth hormone level over the next few hours. The sugar should cause growth hormone production to reduce. However, this does not happen in acromegaly.

Too little growth hormone (deficiency) results in poor growth in children. In adults, it causes a reduced sense of wellbeing, increased fat, increased risk of heart disease and weak heart, muscles and bones.The condition may be present from birth where the cause can be unknown, genetic or due to injury to the pituitary gland (during development or at birth).

Growth hormone deficiency may also develop in adults due to brain injury, a pituitary tumouror damage to the pituitary gland (for example, after brain surgery or radiotherapy for cancer treatment).The main treatment is to replace the growth hormone using injections - either once a day or several times a week.

In the past, growth hormone treatment was stopped at the end of growth. It is now clear that growth hormone contributes to both bone mass and muscle mass reaching the best possible level, as well as reducing fat mass during development to an adult. The specialist is therefore likely to discuss the benefits of continuing growth hormone after growth has completed until age 25 to make sure bone and muscle mass reach the best possible level. Additionally, growth hormone has been linked to a sensation of wellbeing, specifically energy levels. There is evidence that 30-50% of adults with growth hormone deficiency feel tired to a level that impairs their wellbeing. These adults may benefit from lifelong treatment with growth hormone. Taking growth hormone when adult will not result in increased height.

Last reviewed: Feb 2018

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Growth hormone - You and Your Hormones

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Dec 30th, 2018 | Filed under Human Growth Hormone

LONDON--(BUSINESS WIRE)--The global human growth hormone market is expected to post a CAGR of close to 4% during the period 2018-2022, according to the latest market research report by Technavio.

A key factor driving the growth of the global human growth hormone market is the FDA approval of human growth hormone replacement therapy for new indications. Nearly 80% of children with Noonan syndrome have short statures. At present, somatropin injection is the only growth hormone therapy approved for treating short stature in children with Noonan syndrome. Therefore, receiving the FDA approval for human growth hormone for new indications is expected to increase the awareness of the diagnosis. Also, many medical practitioners are expected to use growth hormone therapy in patients with Noonan syndrome.

This market research report on the global human growth hormone market 2018-2022 also provides an analysis of the most important trends expected to impact the market outlook during the forecast period.

This report is available at a USD 1,000 discount for a limited time only: View market snapshot before purchasing

Global human growth hormone market: Increasing incidence of growth disorders

The increasing incidence of growth hormone disorders owing to the deficiency of growth hormone is likely to boost the global human growth hormone market during the forecast period. Moreover, various indications fall under the growth hormone disorders such as Laron syndrome, short stature, Turner syndrome, growth hormone deficiency, acromegaly, septo-optic dysplasia, gigantism, ISS, and Noonan syndrome.

Moreover, there is no impact of biosimilar entry in the human growth hormone market due to various factors such as safety and efficacy as well the quality of regulatory decision-making.

Along with FDA approval of human growth hormone replacement therapy for new indications, the development of long-acting and needle-free deliveries to improve adherence and a strong pipeline of human growth hormone are expected to positively impact the growth of the global human growth hormone market during the forecast period, says a senior analyst at Technavio

Global human growth hormone market: Segmentation analysis

This market research report segments the global human growth hormone market by application (growth hormone deficiency, ISS, Turner syndrome, and PWS) and geographical regions (APAC, EMEA, and the Americas).

The Americas region led the market in 2017 with a market share of over 57%, followed by EMEA and APAC respectively. The Americas region will continue to dominate the market with the highest incremental growth during the forecast period.

Looking for more information on this market? Request a free sample report

Technavios sample reports are free of charge and contain multiple sections of the report such as the market size and forecast, drivers, challenges, trends, and more.

Some of the key topics covered in the report include:

Market Landscape

Market Sizing

Five Forces Analysis

Market Segmentation

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About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavios report library consists of more than 10,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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Global Human Growth Hormone Market 2018-2022 | Increased ...

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Dec 30th, 2018 | Filed under Human Growth Hormone

Dont waste money and risk your reputation on human growth hormone; make your own instead!

Drugs continue to be rife in sport, despite the associated risks to health, career and reputation, their use encouraged by designer modifications that make them more and more difficult to detect.

One group of drugs with large ergogenic effects which continue to pose difficulties in detection are the peptide hormones, incuding EPO, IGF-1 and growth hormone. According to one press report of the time, an empty phial of growth hormone was found in a changing room at the Barcelona Olympics in 1992, fuelling a great amount of speculation on just how widespread this form of drug abuse might be.

In fact, today recombinant human growth hormone (hGH) may well be the drug of choice across a range of sports, from sprinting and other explosive activities to endurance performance. A number of efforts have been made to find a means of catching those who abuse the drug, but even after almost eight years of funding we appear to be no closer to producing a reliable test.

What many athletes and coaches have failed to understand, however, is that athletes can employ specific training regimens and dietary strategies to optimise their natural secretion of human growth hormone (hGH), so inducing those very adaptations to training that others are cheating to achieve.

Human growth hormone is produced in the anterior portion of the pituitary gland, a pea-sized organ suspended just below the brain, which produces no fewer than nine different hormones. Between them these hormones regulate a number of essential physiological functions, including water and energy balance, reproductive activity and the workings of many other glands in the body.

As its name suggests, growth hormone has largely been associated with the function of growth. For centuries scientists believed that puberty was a cut-off point, with human growth hormone (hGH) playing no part in growth or any other function after that. Recent evidence suggests, however, that human growth hormone (hGH) is involved in many physiological processes throughout life, including the turnover of muscle, bone and collagen, the regulation of fat metabolism and the maintenance of a healthier body composition in later life.

A relatively recent discovery is the existence of growth hormone deficiency in adults (GHDA), which has shed further light on the function of this busy little hormone. People with GHDA have a relatively low muscle mass and high body fat, creating a tendency to obesity, an increased risk of heart disease and a greatly reduced exercsie capacity. Treatment of this condition usually requires regular injections of growth hormone.

In general, human growth hormone (hGH) secretion follows a circadian rhythm and is secreted in 6-12 discrete pulses per day, with the largest pulse secreted about an hour after the onset of night-time sleep (around midnight for most people). The release and inhibition of human growth hormone (hGH) are governed by two hypothalamic hormones: growth hormone releasing hormone (GHRH)) and somatostatin. Growth hormone secretion can be triggered by a number of natural stimuli, the most powerful of which are sleep and exercsie.

The fact that exercise acts as a major stimulus for the natural secretion of human growth hormone (hGH) is well known, but there is still little evidence to suggest how this might happen. Various researchers have suggested that it could be triggered by exercise-induced increases in adrenaline, nitric oxide, blood lactate, acidity or nerve activity, either individually or together.

Today there is little doubt that optimising secretion of natural human growth hormone (hGH) is beneficial to sportsmen and women, with none of the many risks associated with hormone abuse, including joint pain, arthritis, abnormal heart growth, muscle weakness, increased blood fats, impaired glucose regulation, diabetes, impotence and, of course, the consequences of breaking the law!

Diet, exercise and sleep patterns all play a role in human growth hormone (hGH) secretion. Since the largest human growth hormone (hGH) surge in a normal day tends to occur around one hour after the onset of night-time sleep, it is vital for athletes to get plenty of it. If the quality of sleep is inadequate there will be a reduction in the volume of human growth hormone (hGH) secreted, with negative consequences for health and fitness. Important preconditions for good quality sleep and optimal human growth hormone (hGH) secretion during sleep include a dark room and a balanced diet containing adequate protein(1). Of course, an adequate quantity of sleep is also required for good health generally, and for most people this means around eight hours.

High-carb diets may be appropriate in many situations but, since hyperglycaemia (elevated blood carbohydrate) tends to switch off human growth hormone (hGH) secretion, this strategy may not be appropriate where optimal adaptation is the priority. Fat taken before exercise has also been found to reduce human growth hormone (hGH) secretion (2).

It is hard to argue against the use of carbohydrate immediately after training in the few days leading up to a competition, when it is important to ensure that carbohydrate stores in the muscles are fully repleted. However, this is not the best strategy for maintaining the release of human growth hormone (hGH) after exercise, particularly if the carbs have a high glycaemic index, as these (sugary) foods stimulate insulin secretion which, in turn, contributes to a reduction in human growth hormone (hGH) (3).

It is also important to drink plenty of water during training, as dehydration has been shown to significantly reduce the exercise-induced human growth hormone (hGH) response (4).

As far as supplementation before exercise is concerned, it has been shown that ingestion of 1.5g of arginine will increase human growth hormone (hGH) secretion by blocking release of the hGH-inhibitor somatostatin, although some studies have suggested this causes gastric disturbance(5). However, 2g of glutamine will lead to elevation of human growth hormone (hGH) 90 minutes later without side effects (6). It may also be a good idea to ingest some amino acids after exercise, as this has been shown to enhance human growth hormone (hGH) secretion too (7).

In terms of training, research has shown that to achieve an elevation of human growth hormone (hGH) above baseline you need to spend at least 10 minutes training at above lactate threshold intensity (8)This results in the biggest volume of human growth hormone (hGH) secreted in response to a single exercise bout, with levels of the hormone declining gradually over a period of an hour. It is also known that multiple daily sessions can give rise to optimal human growth hormone (hGH) secretion over a 24-hour period.

One study investigating the effects of three exercise sessions a day with either 1.5 or three-hour recovery periods between them found that the longer recoveries led to the greatest volume of 24-hour human growth hormone (hGH) secretion (9). Another showed an even larger human growth hormone (hGH) peak in response to sprints on an exercise bike (10).

In the light of the above-mentioned research and current recommendations for both diet and exercise, it might be a good idea to think about periodising diet in a similar way to training. During periods of training, when we are trying to increase muscle mass, minimise body fat and maximise the adaptive response to training, it would seem logical to adopt an hGH-enhancing approach, reverting to a high-carb diet before and during competition.

In summary, then, exercise above lactate threshold induces the secretion of human growth hormone (hGH), promoting the use of fat as fuel. This, in turn, spares muscle carbohydrate, keeps body fat down and muscle mass high and enhances adaptation to specific exercise stimuli. The benefits are clear, but simply switching to high intensity work for the whole year is not the answer; rather, a periodised programme, where the number of sprints or higher intensity workouts alters according to the competitive programme, is the best way forward.

A suggested exercise and dietary strategy for optimising human growth hormone (hGH) secretion is as follows:

Richard Godfrey

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Human growth hormone (hGH) | Peak Performance

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Dec 30th, 2018 | Filed under Human Growth Hormone

Human growth hormone (HGH) is an important hormone produced by your pituitary gland.

Also known as growth hormone (GH), it plays a key role in growth, body composition, cell repair and metabolism (1, 2, 3, 4, 5, 6).

HGH also boosts muscle growth, strength and exercise performance, while helping you recover from injury and disease (4, 7, 8).

Lower HGH levels may negatively impact your quality of life, increase your risk of disease and make you gain fat (9).

Optimal levels are especially important during weight loss, injury recovery and athletic training (10, 11, 12, 13).

Interestingly, your diet and lifestyle choices can have a huge effect on your HGH levels (6, 14).

Here are 11 evidence-based ways to increase human growth hormone (HGH) levels naturally.

The amount of body fat you carry is directly related to your HGH production (3).

Those with higher body fat levels or more belly fat will likely have impaired HGH production and an increased risk of disease.

One study observed that individuals with three times the amount of belly fat as the control group had less than half their amount of HGH (15).

As shown in the graph below, one study monitored the 24-hour release of HGH and found a large decline in those with more abdominal fat.

Interestingly, research suggests that excess body fat affects HGH levels more in men. However, lowering body fat is still key for both genders (15, 16).

One study found that obese individuals had lower levels of IGF-1 a growth-related protein as well as HGH. After losing a significant amount of weight, their levels returned to normal (17).

Belly fat is the most dangerous type of stored fat and linked to many diseases. Losing belly fat will help optimize your HGH levels and other aspects of your health.

Studies show that fasting leads to a major increase in HGH levels.

One study found that three days into a fast, HGH levels increased by over 300%. After one week of fasting, they had increased by a massive 1,250% (18).

Other studies have found similar effects, with double or triple HGH levels after just 23 days of fasting (19, 20, 21).

However, continuous fasting is not sustainable in the long term. Intermittent fasting is a more popular dietary approach that limits eating to brief time periods.

Multiple methods of intermittent fasting are available. One common approach is a daily eight-hour eating window with a 16-hour fast. Another involves eating only 500600 calories two days per week (22, 23).

Intermittent fasting can help optimize HGH levels in two main ways. First, it can help you drop body fat, which directly affects HGH production (24, 25, 26, 27).

Second, it'll keep your insulin levels low for most of the day, as insulin is released when you eat. Research suggests that insulin spikes can disrupt your natural growth hormone production (28, 29).

As shown in the graph below, one study found large differences in HGH levels on the fasting day compared to the eating day (30).

Shorter 1216-hour fasts likely help as well, though more research is needed to compare their effects against full-day fasts.

When taken alone, arginine may boost HGH.

Though most people tend to use amino acids like arginine alongside exercise, several studies show little or no increase in HGH levels (31, 32, 33).

However, when arginine was taken on its own without any exercise there was a significant increase in this hormone (32, 33).

Other non-exercise studies also support the use of arginine to boost HGH.

One study examined the effects of taking either 45 or 114 mg of arginine per pound (100 or 250 mg per kg) of body weight, or around 610 or 1520 grams per day.

They found no effect for the lower dose, but participants taking the higher dose saw around a 60% increase in HGH levels during sleep (34).

An increase in insulin can lower HGH production.

Refined carbs and sugar raise insulin levels the most, so reducing your intake may help optimize growth hormone levels (24, 25).

One study found that healthy individuals had 34 times higher HGH levels than people with diabetes, as well as impaired carb tolerance and insulin function (35).

Along with directly affecting insulin levels, excess sugar intake is a key factor in weight gain and obesity, which also affect HGH levels.

That said, the occasional sweet treat will not impact your HGH levels in the long term.

Aim to achieve a balanced diet since what you eat has a profound effect on your health, hormones and body composition.

Your body naturally releases significant amounts of HGH, especially at night (36, 37).

Given that most meals cause a rise in insulin levels, some experts suggest avoiding food before bedtime (25).

In particular, a high-carb or high-protein meal may spike your insulin and potentially block some of the HGH released at night (38).

Keep in mind that insufficient research exists on this theory.

Nevertheless, insulin levels normally decrease 23 hours after eating, so you may wish to avoid carb- or protein-based meals 23 hours before bedtime.

GABA is a non-protein amino acid that functions as a neurotransmitter, sending signals around your brain.

As a well-known calming agent for your brain and central nervous system, it's often used to aid sleep. Interestingly, it may also help increase your HGH levels (39).

One study found that taking a GABA supplement led to a 400% increase in HGH at rest and a 200% increase following exercise (40).

GABA may also increase HGH levels by improving your sleep, since your night-time growth hormone release is linked to sleep quality and depth (41, 42).

However, most of these increases were short-lived and GABA's long-term benefits for growth hormone levels remain unclear (39, 40).

Exercise is one of the most effective ways to significantly raise your HGH levels.

The increase depends on the type of exercise, intensity, food intake around the workout and your bodys own traits (43, 44, 45, 46, 47, 48, 49).

As shown by the black bars in the graph below, very large increases in HGH were seen in a weight lifting session with limited rest periods (10, 46).

Due to its metabolic nature and increase in lactic acid, high-intensity exercise increases HGH the most. However, all forms of exercise are beneficial (43, 44).

You can perform repeated sprints, interval training, weight training or circuit training to spike your HGH levels and maximize fat loss (46, target="_blank"50, 51).

As with the supplement methods, exercise mainly provides short-term spikes.

Then again, over the long term, exercise may optimize your hormone function and decrease body fat, both of which will benefit your HGH levels.

Some exercise supplements can optimize performance and boost your HGH levels.

In one study, 4.8 grams of beta-alanine before a workout increased the number of repetitions performed by 22% (52).

It also doubled peak power and boosted HGH levels compared to the non-supplement group (52).

Another study demonstrated that a sugary sports drink increased HGH levels towards the end of a workout. However, if youre trying to lose fat, the drinks extra calories will negate any benefit from the short-term HGH spike (53).

Studies have shown that protein shakes, both with and without carbs, can boost HGH levels around workouts (48, 49).

The majority of HGH is released in pulses when you sleep. These pulses are based on your body's internal clock or circadian rhythm.

As you can see from the graph below, the largest pulses occur before midnight with some smaller pulses in the early morning (36, 37).

Studies have shown that poor sleep can reduce the amount of HGH your body produces (42).

In fact, getting an adequate amount of deep sleep is one of the best strategies to enhance your long-term HGH production (37, 42).

Here are a few simple strategies to help optimize your sleep:

Melatonin is a hormone that plays an important role in sleep and blood pressure regulation (54).

Melatonin supplements have become a popular sleep aid that can increase both the quality and duration of your sleep (55, 56, 57, 58, 59, 60, 61).

While good sleep alone may benefit HGH levels, further research has shown that a melatonin supplement can directly enhance HGH production (58, 62, 63, 64).

Melatonin is also fairly safe and non-toxic. However, it may alter your brain chemistry in some ways, so you may want to check with a doctor before using it (65).

To maximize its effects, take 15 mg around 30 minutes before bed. Start with a lower dose to assess your tolerance, then increase if needed.

Several other supplements may enhance human growth hormone production, including:

While all of these supplements may increase your HGH levels, studies indicate theyre only effective in the short term.

As with other key hormones such as testosterone and estrogen having healthy levels of growth hormone is important.

HGH helps your body with metabolism, cell repair and other vital functions.

By following the tips above, you can increase your HGH levels fairly easily.

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11 Ways to Boost Human Growth Hormone (HGH) Naturally

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Nov 20th, 2018 | Filed under Human Growth Hormone

by: Yuri Elkaim

If there was ever a hormone youd want for a best friend, it would be human growth hormone.

While its often associated with steroid use, human growth hormone (HGH) is so much more than a tool to increase muscle mass. In fact, once you learn all the benefits of HGH, youll probably want to do what you can to take advantage of it naturally.

HGH also plays a role in:

HGHs effects are so potent its now calledthe fountain of youth hormone due to its ability to turn back the aging clock.

So what exactly is HGH, and what makes it so powerful?

Secreted by the pituitary gland, HGH is an anabolic hormone responsible for spurring growth throughout childhood and adolescence, granting us the lean, muscular frame we often carry during these years.

This growth effect is mimicked when HGH is taken in supplement form, resulting in rapid changes in body composition resulting in leanness and added muscle.

Its also responsible for collagen and muscle tissue synthesis, which is one of the major reasons HGH is known for its anti-aging effects, especially inskin elasticity (1).

Now, you might be thinking, Excellent! How do I kickstart my HGH production and/or where can I pick up a bottle (or 10)?

Unfortunately, there are two major caveats when it comes to HGH.

One: natural HGH production begins to decline once we reach our 20s, resulting in a progressive loss of muscle mass and increase in fat tissue.

This loss continues at about 10 to 15 percent each year after the age of 30 and leads to the standard symptoms of aging like sagging skin, loss of energy and endurance, and graying hair.

Two: while HGH injections are a popular option for the elderly and children with deficiencies and growth disorders, supplement use by the general population is still illegal.

Which means were left to our own devices when it comes to increasing our HGH levels.

Luckily, there are several simple ways to naturally boost our levels of HGH, without supplements or injections.

Take a look below at the top three ways we can boost this youth hormone.

Human growth hormone is released not in a continuous flow, but in pulses. Andsome of these major pulses occur during deep sleep.

This occurs because growth hormone plays a role in repairing and restoring the body, which often takes place during our slumber.

But not just any slumber. Specifically, our brains secrete growth hormone during the third stage of the sleep cycle, when ourbrain temperature, breathing and heart rates, and blood pressure are all at their lowest levels (2).

To get to this stage, we have to bypass stage two, which is where most adults usually spend 45 to 50 percent of their time asleep.

To optimize HGH levels, we want to get into that third stage of sleep, also known as the slow wave stage (3).This requires a deep level of sleep that is often interrupted either by our sleep environment, stress, diet, or any one of a number of factors.

So, to get the growth hormone release we want, we have to employ tactics to help us sleep more deeply, more often.

Even though we might know that deep sleep is good for us and helps to stimulate growth hormone, getting enough of it can be a real challenge.

Check out these tips for longer,deeper sleep.

1. Get more rays.

Sunlight plays a key role in the secretion of melatonin a hormone produced in the pineal gland responsible for our sleep-wake cycles.

Getting more sunlight during the day naturally helps the body signal the release of melatonin when it gets dark at night. The release makes us feel sleepy and ready for bed.

2. Get (less) technical.

Those seemingly harmless devices we often carry into bed (tablets, phones, etc.) actually work against us when it comes to sleep.

The artificial blue light emitted from the screens actually disturbs normal hormone levels, disrupting our sleep cycles (4).

Thats why I recommend removing the TV from your bedroom, and also avoiding bright screens 2 to 3 hours before bedtime.

3. Limit caffeine.

Obviously, you dont want to guzzle down a fully caffeinated cup of coffee before going to bed, but you should also try to limit caffeineduring the day.

Why? Caffeine does a number on your hormones and metabolism that can potentially play a role in getting a deep sleep (5).

A few other tricks to get a deeper sleep include: developing a regular bedtime, supplementing with magnesium, and creating a sleep journal noting anything that effects your sleep.

Believe it or not, abstaining from eating is also one of the best ways to stimulate human growth hormone.In fact, in one study, fasting caused participants serum growth hormone levels to increase by a whopping 500 percent (6)!

Now (before panic sets in), know that Im not talking about embarking on a month-long water fast in order to boost growth hormone.

By fasting, Im actually referring to what is termed as intermittent fasting. This type of fasting involves eating daily, but only in a certain window of time.

For instance, the most popular form of intermittent fasting involves simply skipping breakfast and eating your first meal at lunch time. In doing this, youll essentially be performing a daily 14- to 16-hour fast from dinner the night before to lunch the next day.

At this point you may be thinking (due to years of conventional wisdom and conditioning) that skipping any meal is a recipe for a wrecked metabolism.

No worries.

Studies show that fasting for short periods of time actually has no effect on metabolism. In fact, researchers have found there is no difference in calories burned over a 24-hour period between people who eat breakfast and those that skip it altogether (7).

The breakfast skippers metabolisms were unharmed by daily fasting and there was no boosting of the breakfast eaters metabolisms.

So much for those promises of breakfast kickstarting our metabolisms, right?

To try out fasting for yourself, simply start by skipping breakfast a few days a week to see how you feel. One thing to remember, however, is to not ingest any calories during the fasting period no milk or sugar in your tea, no juices, etc.

If your last meal is at 6 p.m., then your fast will begin from 9 p.m. (our bodies take about 3 hours to digest a main meal), which means your 16-hour fast will end around 1 p.m. the next day.

Notice the shorter window of eating time. If you find this daunting at first, feel free to increase your fast time by an hour every dayuntil you feel more comfortable not eatingbreakfast.

[Related:How to Do Intermittent Fasting: 19 Popular Questions Answered]

As with deep sleep, intense exercise has also been shown to act as a natural human growth hormone stimulator.

There are several theories why this occurs, but researchers agree that it seems to be in response to the breaking down of muscle including resistance training and any other form of exercise that involves significant intensity (8).

Its true: regardless of the activity, it really is all in the intensity.

So, how can we, as non-professional athletes, get the intensity levels required to produce more growth hormone?

The answer is high-intensity interval training (HIIT).

HIIT involves alternating periods of high-intensity activity (sprints, circuit training, etc.) with short periods of rest, for a total of 15 to 30 minutes of exercise.

[Related:5 Powerful Jump Rope HIIT Workouts (#2 Is My Favorite)]

A simple HIIT workout can include sprints, jump rope, cycling, rowing, and/or circuit training with or without weights. The key is to go all out in effort during your work phase.

For instance, you do sprints at maximum effort for 30 seconds, then recover for 60 seconds, repeating for a total of 15 to 30 minutes. Know that you can slowly increase the duration your sprint time or decrease your rest time if youre a beginner.

Combining these three human growth hormone stimulators into your daily routine will have you naturally increasing you levels without the need for injections or additional supplements.

Get ready to sleep, fast, and HIIT your way to increased muscle (and, perhaps, the fountain of youth!).

Ready to try the power of interval training I talked about in this post? Ive got the ultimate guide for you.

Download my follow-along interval cardio workoutyoull burn more fat and improve your cardio endurance in just 5 minutes.

MySpeed Burst Interval Workoutis a$19 value, but you can get it right now for FREE.

All you have to do is click the banner below and download it now.

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Sep 28th, 2018 | Filed under Human Growth Hormone

This report studies the global market size of Human Growth Hormone (hGH) in key regions like North America, Europe, Asia Pacific, Central & South America and Middle East & Africa, focuses on the consumption of Human Growth Hormone (hGH) in these regions.This research report categorizes the global Human Growth Hormone (hGH) market by players/brands, region, type and application. This report also studies the global market status, competition landscape, market share, growth rate, future trends, market drivers, opportunities and challenges, sales channels, distributors and Porter's Five Forces Analysis.

In 2017, the global Human Growth Hormone (hGH) market size was million US$ and is forecast to million US in 2025, growing at a CAGR of from 2018. The objectives of this study are to define, segment, and project the size of the Human Growth Hormone (hGH) market based on company, product type, application and key regions.

The various contributors involved in the value chain of Human Growth Hormone (hGH) include manufacturers, suppliers, distributors, intermediaries, and customers. The key manufacturers in the Human Growth Hormone (hGH) includeEli Lilly and CompanyFerring Holding SAGenentechMerck & Co.Novo NordiskPfizerSandoz International GmbHIpsen

Market Size Split by TypeRecombinant Human Growth Hormone (rhGH)Human Growth Hormone (rhGH)Market Size Split by ApplicationGrowth Hormone DeficiencyTurner SyndromeIdiopathic Short StaturePrader-Willi SyndromeSmall for Gestational AgeOthers

Market size split by RegionNorth AmericaUnited StatesCanadaMexicoAsia-PacificChinaIndiaJapanSouth KoreaAustraliaIndonesiaSingaporeMalaysiaPhilippinesThailandVietnamEuropeGermanyFranceUKItalySpainRussiaCentral & South AmericaBrazilRest of Central & South AmericaMiddle East & AfricaGCC CountriesTurkeyEgyptSouth Africa

The study objectives of this report are:To study and analyze the global Human Growth Hormone (hGH) market size (value & volume) by company, key regions/countries, products and application, history data from 2013 to 2017, and forecast to 2025.To understand the structure of Human Growth Hormone (hGH) market by identifying its various subsegments.To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).Focuses on the key global Human Growth Hormone (hGH) manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.To analyze the Human Growth Hormone (hGH) with respect to individual growth trends, future prospects, and their contribution to the total market.To project the value and volume of Human Growth Hormone (hGH) submarkets, with respect to key regions (along with their respective key countries).To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.To strategically profile the key players and comprehensively analyze their growth strategies.

In this study, the years considered to estimate the market size of Human Growth Hormone (hGH) are as follows:History Year: 2013-2017Base Year: 2017Estimated Year: 2018Forecast Year 2018 to 2025

This report includes the estimation of market size for value (million US$) and volume (Units). Both top-down and bottom-up approaches have been used to estimate and validate the market size of Human Growth Hormone (hGH) market, to estimate the size of various other dependent submarkets in the overall market. Key players in the market have been identified through secondary research, and their market shares have been determined through primary and secondary research. All percentage shares, splits, and breakdowns have been determined using secondary sources and verified primary sources.

For the data information by region, company, type and application, 2017 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

Table of Contents

1 Study Coverage1.1 Human Growth Hormone (hGH) Product1.2 Key Market Segments1.3 Key Manufacturers Covered1.4 Market by Type1.4.1 Global Human Growth Hormone (hGH) Market Size Growth Rate by Type1.4.2 Recombinant Human Growth Hormone (rhGH)1.4.3 Human Growth Hormone (rhGH)1.5 Market by Application1.5.1 Global Human Growth Hormone (hGH) Market Size Growth Rate by Application1.5.2 Growth Hormone Deficiency1.5.3 Turner Syndrome1.5.4 Idiopathic Short Stature1.5.5 Prader-Willi Syndrome1.5.6 Small for Gestational Age1.5.7 Others1.6 Study Objectives1.7 Years Considered

2 Executive Summary2.1 Global Human Growth Hormone (hGH) Market Size2.1.1 Global Human Growth Hormone (hGH) Revenue 2016-20252.1.2 Global Human Growth Hormone (hGH) Sales 2016-20252.2 Human Growth Hormone (hGH) Growth Rate by Regions2.2.1 Global Human Growth Hormone (hGH) Sales by Regions2.2.2 Global Human Growth Hormone (hGH) Revenue by Regions

3 Breakdown Data by Manufacturers3.1 Human Growth Hormone (hGH) Sales by Manufacturers3.1.1 Human Growth Hormone (hGH) Sales by Manufacturers3.1.2 Human Growth Hormone (hGH) Sales Market Share by Manufacturers3.1.3 Global Human Growth Hormone (hGH) Market Concentration Ratio (CR5 and HHI)3.2 Human Growth Hormone (hGH) Revenue by Manufacturers3.2.1 Human Growth Hormone (hGH) Revenue by Manufacturers (2016-2018)3.2.2 Human Growth Hormone (hGH) Revenue Share by Manufacturers (2016-2018)3.3 Human Growth Hormone (hGH) Price by Manufacturers3.4 Human Growth Hormone (hGH) Manufacturing Base Distribution, Product Types3.4.1 Human Growth Hormone (hGH) Manufacturers Manufacturing Base Distribution, Headquarters3.4.2 Manufacturers Human Growth Hormone (hGH) Product Category3.4.3 Date of International Manufacturers Enter into Human Growth Hormone (hGH) Market3.5 Manufacturers Mergers & Acquisitions, Expansion Plans

4 Breakdown Data by Type4.1 Global Human Growth Hormone (hGH) Sales by Type4.2 Global Human Growth Hormone (hGH) Revenue by Type4.3 Human Growth Hormone (hGH) Price by Type

5 Breakdown Data by Application5.1 Overview5.2 Global Human Growth Hormone (hGH) Breakdown Data by Application

6 North America6.1 North America Human Growth Hormone (hGH) by Countries6.1.1 North America Human Growth Hormone (hGH) Sales by Countries6.1.2 North America Human Growth Hormone (hGH) Revenue by Countries6.1.3 United States6.1.4 Canada6.1.5 Mexico6.2 North America Human Growth Hormone (hGH) by Type6.3 North America Human Growth Hormone (hGH) by Application6.4 North America Human Growth Hormone (hGH) by Company

7 Europe7.1 Europe Human Growth Hormone (hGH) by Countries7.1.1 Europe Human Growth Hormone (hGH) Sales by Countries7.1.2 Europe Human Growth Hormone (hGH) Revenue by Countries7.1.3 Germany7.1.4 France7.1.5 UK7.1.6 Italy7.1.7 Russia7.2 Europe Human Growth Hormone (hGH) by Type7.3 Europe Human Growth Hormone (hGH) by Application7.4 Europe Human Growth Hormone (hGH) by Company

8 Asia Pacific8.1 Asia Pacific Human Growth Hormone (hGH) by Countries8.1.1 Asia Pacific Human Growth Hormone (hGH) Sales by Countries8.1.2 Asia Pacific Human Growth Hormone (hGH) Revenue by Countries8.1.3 China8.1.4 Japan8.1.5 Korea8.1.6 India8.1.7 Australia8.1.8 Indonesia8.1.9 Malaysia8.1.10 Philippines8.1.11 Thailand8.1.12 Vietnam8.1.13 Singapore8.2 Asia Pacific Human Growth Hormone (hGH) by Type8.3 Asia Pacific Human Growth Hormone (hGH) by Application8.4 Asia Pacific Human Growth Hormone (hGH) by Company

9 Central & South America9.1 Central & South America Human Growth Hormone (hGH) by Countries9.1.1 Central & South America Human Growth Hormone (hGH) Sales by Countries9.1.2 Central & South America Human Growth Hormone (hGH) Revenue by Countries9.1.3 Brazil9.2 Central & South America Human Growth Hormone (hGH) by Type9.3 Central & South America Human Growth Hormone (hGH) by Application9.4 Central & South America Human Growth Hormone (hGH) by Company

10 Middle East and Africa10.1 Middle East and Africa Human Growth Hormone (hGH) by Countries10.1.1 Middle East and Africa Human Growth Hormone (hGH) Sales by Countries10.1.2 Middle East and Africa Human Growth Hormone (hGH) Revenue by Countries10.1.3 GCC Countries10.1.4 Turkey10.1.5 Egypt10.1.6 South Africa10.2 Middle East and Africa Human Growth Hormone (hGH) by Type10.3 Middle East and Africa Human Growth Hormone (hGH) by Application10.4 Middle East and Africa Human Growth Hormone (hGH) by Company

11 Company Profiles11.1 Eli Lilly and Company11.1.1 Eli Lilly and Company Company Details11.1.2 Company Description11.1.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.1.4 Human Growth Hormone (hGH) Product Description11.1.5 Recent Development11.2 Ferring Holding SA11.2.1 Ferring Holding SA Company Details11.2.2 Company Description11.2.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.2.4 Human Growth Hormone (hGH) Product Description11.2.5 Recent Development11.3 Genentech11.3.1 Genentech Company Details11.3.2 Company Description11.3.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.3.4 Human Growth Hormone (hGH) Product Description11.3.5 Recent Development11.4 Merck & Co.11.4.1 Merck & Co. Company Details11.4.2 Company Description11.4.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.4.4 Human Growth Hormone (hGH) Product Description11.4.5 Recent Development11.5 Novo Nordisk11.5.1 Novo Nordisk Company Details11.5.2 Company Description11.5.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.5.4 Human Growth Hormone (hGH) Product Description11.5.5 Recent Development11.6 Pfizer11.6.1 Pfizer Company Details11.6.2 Company Description11.6.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.6.4 Human Growth Hormone (hGH) Product Description11.6.5 Recent Development11.7 Sandoz International GmbH11.7.1 Sandoz International GmbH Company Details11.7.2 Company Description11.7.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.7.4 Human Growth Hormone (hGH) Product Description11.7.5 Recent Development11.8 Ipsen11.8.1 Ipsen Company Details11.8.2 Company Description11.8.3 Sales, Revenue and Gross Margin of Human Growth Hormone (hGH)11.8.4 Human Growth Hormone (hGH) Product Description11.8.5 Recent Development

12 Market Opportunities, Challenges, Risks and Influences Factors Analysis12.1 Market Opportunities and Drivers12.2 Market Challenges12.3 Market Risks/Restraints12.4 Key World Economic Indicators

13 Value Chain and Sales Channels Analysis13.1 Value Chain Analysis13.1.1 Typical Suppliers of Key Human Growth Hormone (hGH) Raw Material13.1.2 Human Growth Hormone (hGH) Customers13.2 Sales Channels Analysis13.2.1 Sales Channels Analysis13.2.2 Distributors

14 Research Findings and Conclusion

15 Appendix15.1 Research Methodology15.1.1 Methodology/Research Approach15.1.1.1 Research Programs/Design15.1.1.2 Market Size Estimation15.1.1.3 Market Breakdown and Data Triangulation15.1.2 Data Source15.1.2.1 Secondary Sources15.1.2.2 Primary Sources15.2 Author Details15.3 Disclaimer

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Human Growth Hormone (hGH) Market Report Research ...

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Sep 28th, 2018 | Filed under Human Growth Hormone

If youre a sports fan, youve probably heard of human growth hormone more commonly known as HGH and associate it with cheating and steroid use. However, did you know that HGH is a natural testosterone booster thats produced on its own and provides many important benefits? Its true.

Human growth hormoneis naturally produced in the pituitary gland and plays a vital role in cell regeneration, growth and maintaining healthy human tissue, including that of the brain and various vital organs. Once secreted, HGH remains active in the bloodstream for a few minutes, allowing just enough time for the liver to convert it into growth factors, the most crucial being insulin-like growth factor (IGF-1), which has growth-promoting properties on every cell in the body.

The study of human growth hormone is a little more than 100years old, and synthetic human growth hormone was first developed in the 1980s and approved by the FDA for specific uses in adults and children. (1) Lets find out why.

Human growth hormonecan be injected in larger doses to promote weight loss and increase muscle size while a small doses can be used for general recovery, health and ignite the anti-aging process. Presently, there isa growing list of benefits of HGH treatment in children, adolescents and adults, such as:

1. Increased Muscle Strength

Human growth hormone has been known to improve physical capacity of individuals through stimulating collagen synthesis in the skeletal muscle and tendons, increasing muscle strength and improving exercise performance as a result.

In the International Journal of Endocrinology, a study with 14healthy men at the ages of 50to 70were randomized into two groups. Seven subjects were administered HGH therapy withseven placebo subjects, and they were re-evaluated after six months. After six months, there was a significant increase in the leg press responsiveness muscles in the growth hormone group.

Overall, the study concluded an increased muscle strength in the lower body after human growth hormone was administered in healthy men. In HGH-deficient adults, participants who were administered long-term HGH therapy experienced normalization of muscle strength, increased exercise capacity, and improved thermoregulation and body composition. (2)

2. Better Fracture Healing

Numerous of local growth factors and hormones are responsible for regulating mineral and bone metabolism, along with fracture healing. Administration of human growth hormone has been shown to speed up the regeneration of bone, making it a key part of bone healing. Applying growth factors like IGF-1 isknown to stimulate the metabolism of bone.

In a study published in the journal BONE, growth hormone was systemically applied to recombinant species-specific rats by subcutaneous injections and was compared to the placebo group. As a result, the local growth factor application revealed a stronger effect on fracture healing than the systemic human growth hormone injection. These observations suggest that the local application of growth hormone speeds up fracture healing significantly without systemic adverse effects. (3)

Human growth hormone plays a crucial role in the repair of wear and tear and expedites healing. Researchers have reported the beneficial effects of HGH in enhancing the healing of injuries and wounds significantly. A randomized, controlled, double-blinded study forsix months of HGH therapy or placebo in 28healthy older men with low baseline plasma IGF-1 was conducted at the University of Californias Department of Medicine. As a result, healthy older men who were administered growth hormone had enhanced collagen deposition during the wound-healing process, helping the healing process. (4)

3. EnhancedWeight Loss

Obese individuals have limited response to growth hormone stimuli release, and after successful reduction of weight, growth hormone responsiveness can bepartial or complete. Growth hormone accelerates lipolysis,the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids, and impaired secretion of human growth hormone leads to loss of lipolytic effect.

Dietary restrictions and growth hormone treatment effects on anabolic and lipolytic actions as well as the changes in growth hormone secretions and insulin wereinvestigated in a study published in Hormone Research. Twenty-four obese participants were on a hypocaloric diet and treated with recombinant human growth hormone or a placebo in a double-blinded, 12-week randomized study. As a result, growth hormone treatment caused a 1.6-fold increase in weight loss, with thegreatest loss being visceral fat compared to the placebo.

In the placebo group, lean body mass was lost, whereas lean body mass was gained in the growth hormone group. This study suggests that in obese participants who eata caloric-restriction diet, growth hormone accelerates the loss of body fat and improves growth hormone secretion. Thus, human growth hormone can serve a therapeutic role tohelp obese people lose weight. (5)

4. Stronger Bones

The pituitary gland stimulates the release of growth hormone and is essential for regulating bone growth, especially during puberty. Growth hormone stimulates the production of IGF-1, which is produced in the liver and released in the blood. With age, human growth hormone decreases and may be the cause of older individuals not being able to form or replace bone rapidly. The IGF-1/growth hormone duo stimulates bone-forming and bone-resorbing cells, leading to increased bone mass. (6)

5. Reduced Cardiovascular Disease Risk

Adults who are growth hormone-deficient have an increased risk for cardiovascular disease, leading to decreased life expectancy. In Sweden,104patients who are growth hormone-deficient were studied for cardiovascular disease risk. These patients had higher body mass and triglyceride concentrations compared to controls. These results suggest lipoprotein metabolism is altered by growth hormone deficiency, increasing the risk for cardiovascular disease. (7)

6. Improvement in Erectile Dysfunction

Its been suggested in recent studies that human growth hormone is responsible for male reproductive function and sexual maturation while deficiency is associated with loss of sexual erection and desire. Thirty-five healthy adult men and 45participants with erectile dysfunction were exposed to tactile and visual stimuli in order to elicit penile tumescence in a German study. The increase in growth hormone was greater than 90percentasdetermined during developing penile tumescence, followed by a transient decrease afterward.

This study suggests that penile erection maybe induced by growth hormone through its stimulating activity on human corpus cavernosum smooth muscle, making it a potential natural remedy for impotence. (8)

7. Decreased Obesity

Insulin resistance and visceral/abdominal obesity are commonin adults with hormone growth deficiency. Abdominal obesity is prevalent in individuals who show low growth hormone and insulin-like growth hormone serum concentrations as well. Human growth hormone treatment has demonstrated positive results in adults who are growth hormone-deficient in treating obesity naturally.

Thirtymen ages 4866with abdominal/visceral obesity were treated with recombinant human growth hormone in a nine-month, randomized, double-blind study published in the Journal of Clinical Endocrinology & Metabolism. Abdominal and visceral adipose tissue decreased along with diastolic blood pressure, and improved insulin sensitivity wasone of the favorable benefits of human growth hormone found. (9)

8. Better Mood and Cognitive Function

Quality of life and psychological well-being arerestored when growth hormone therapy in growth hormone-deficient adults isadministered. A Lithuanian study investigated the changes in cognitive function, mood and concentration from baseline after six months of treatment with human recombinant growth hormone. Eighteen adult patients with HGH deficiencyparticipated in the study, and growth hormone was administered in 12 IU per week.

As a result, cognitive function and mood significantly increased after six months of therapy, according to mood scales. This study suggests that administering growth hormone can be a possible treatment option to improve cognitive function and mood in adults who are growth hormone-deficient. (10)

9. Better Sleep

The majority of the growth hormone pulsatile secretion happens just after the onset of sleep and continues to rise when the first hours of sleep are reached. Individuals who are going through sleep deprivation, such as people who work the night shift or late studiers, can be affected negatively throughout the day. Lack of sleep alters pituitary and hypothalamus function, further altering growth hormone release time.

When sleep was deprived for 24 to 36hours in a study conducted by the University of Chicagos Department of Medicine, human growth hormone release was drastically decreased and noticeably decreased in growth hormone peak values at night. The 24-hour pulse rate of growth hormone became random and more frequent throughout these waking hours. This study suggests that sleep deprivation can reduce growth hormone release the morning after and can severely disturb and alter the sleep-wake cycle. (11)

Signs and symptoms of growth hormone deficiency vary with age, and children can have different symptoms than an adult. Childrenbeing significantly shorter than children their age and grow less than two inches per year are common symptoms of growth hormone deficiency. Children with normal levels grow about 2.5 inches a year from age 1until they hit puberty, when they can grow up to four inches a year. However, a decline in human growth hormone does not have any impact on a childs intelligence.

Other symptoms of growth hormone deficiency in children include: (12)

Adults may experience a combination of symptoms from human growth hormone deficiency, including: (13)

More women are now using HGH for its anti-aging and weight-loss properties. Deficiency in human growth hormone in women is due to pituitary gland not producing enough HGH.

In women, human growth hormone levels start to decline in their early 20s, and signs of HGH deficiency include dry skin, thinning hair, greater belly fat and the development of wrinkles.

Its been reported in studies that women secrete greater amounts of growth hormone than men, despite having similar reference ranges of serum IGF-1. Recently, there are significant clinical differences in the responses of HGH treatment in adults with HGH deficiency and a need to adjust the dose of recombinant human growth hormone. Adequate HGH levels help women improve an appropriate body-fat ratio and elasticity in skin. Risk of osteoporosis is reduced when HGH levels in women are balanced. Intramuscular HGH injections can helpnormalize sleep patterns, improved skin elasticity, help loseexcess fat and enhance the immune system.

Men are likely to feel the first signs of aging after 35old, such as loss of libido, weakness, baldness and memory loss. Human growth hormone has a positive impact on men, giving them the physical ability to perform in sports, which is why men often go through HGH treatment during intense training. Men who are treated with HGH experience reduction of fat, skin tightening, hair becomes healthier and thicker, and erectile dysfunction is corrected. (14)

1. High-Intensity Exercise

Its well-documented in variou studies that exercise-induced growth hormone response increases HGH secretion. Research suggests that the exercise-induced growth hormone plus endurance exercise associated with load, intensity, duration and frequency are the determining factors in the regulation of HGH secretion.

An exercise intensity above lactate threshold and for a minimum of 10minutes elicits the greatest stimulus to the secretion of HGH. HIIT workouts areeffective in promoting beneficial well-being, health and positive training outcomes, while stimulating HGH. (15)

2. L-glutamine

Supplementing with L-glutamine is known for enhancing exercise performance, maintaining acid-base balance and increasing the storage of glycogen in muscle. In an Iranian study, 30healthy non-athlete males were randomly divided into placebo and glutamine supplementation groups and put through an eight-week resistance training program. Both groups performed the same weight training program three days a week for eight weeks. Both groups increased in performance, but the glutamine groups showed greater increases in lower- and upper-body strength, explosive muscle power, blood testosterone, IGF-1, and HGH compared to the placebo group. (16)

3. L-arginine

Most studies have shown when administering oral L-arginine to participants, arginine alone increases the resting growth hormone levels at least 100percent, while exercise can increase growth hormone levels by 300 percentto 500percent. (17)

4. A-GPC

According to a study in the 2008 issue of the Journal of the International Society of Sports Nutrition, alpha-glycerylphosphorylcholine (A-GPC) might increase human growth hormone levels. Participants who consumed 600 milligrams of A-GPC two hours before resistance exercise had increased HGH levels post-exercise compared to those given a placebo. (18)

5. Laughter

Researchers Stanley Tan and Lee Berk at Loma Linda University in Loma Linda, Calif., observed that two hormones, human growth hormone and endorphins, were increased by27 percentand 87 percent, respectively, when participants anticipated watching a humorous video. (19)

6. Liver Detox

HGH stimulates the liver into producing IGF-1, which is released into the body to stimulate the production of cells that are responsible for cell proliferation, increased muscle mass and increased energy. An individual would never experience the full benefits HGH has to offer if experiencing poor liver function, cirrhosis, fatty liver and non-alcoholic fatty liver disease. (20) Thus, if you naturally want to increase HGH, you should go on a liver cleanse.

7. Vitamin C

Studies have observed the correlation of reduced vitamin C concentration in decreased growth hormone secretion, obese patients, increased waist-hip ratio and increased heart disease risk, which is why consuming more vitamin C foods may help increase HGH. (21)

Unfortunately, HGH has side effects. Major side effects include enlargement of the fingers and toes, skeletal changes, growth of the orbit, and lengthening of the jaw. The internal organs also can enlarge, and cardiomegaly is often one of the causes of death associated with HGH abuse.

Since skeletal muscle increases in size, there are often complaints of muscle weakness and occasional feeling of pins and needles sensation, known as carpal tunnel syndrome, which are particularly observed by individuals who take daily doses of four IU of HGH or higher. Individuals also notice fingers feeling swollen or face feeling fuller at doses of four IU and above. This side effect is temporary and has been shown to goaway when the dose is lowered within two weeks after the cycle is discontinued. (22)

Another consequence of increased protein synthesis during HGH abuse includeschanges to the skin, such as thickening and coarsening, known as elephant epidermis. The combination of side effects, particularly cardiomegaly, hyperlipidemia, hyperglycemia, usually contributes to a shortened life span in those suffering from overproduction of HGH. (23)

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9 Benefits of Human Growth Hormone (Along with Side ...

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Sep 17th, 2018 | Filed under Human Growth Hormone

There are a number of excellent reasons to use the human growth hormone, or HGH. Some people use it in order to look and feel younger, or to fight off the physical and mental effects of the natural aging process. Its also used to treat serious illnesses such as intestinal diseases and wasting syndromes that are often a result of cancer or HIV. Most people use this steroid in order to increase their strength and enhance their athletic performance. It allows your body to develop at a faster than normal rate, which means you can count on a faster, stronger and more intense physical performance in the gym, on the track or while playing nearly any sport.

What is HGH?

The human growth hormone is produced naturally by your body. It comes from the pituitary gland, and it is the reason that babies grow into children and children grow into adolescents and then adolescents grow into adults. It keeps your body on track for development and growth. This hormone also regulates a lot of your bodys functions. It helps deliver fluids to different organs and body parts and it also plays a role in your metabolism and your bloods ability to process sugars. When its taken to improve athletic performance, it can jumpstart your workouts and give you an advantage as a competitor.

The Benefits of HGH

This is one of the most powerful products on the market because it does things that other steroids cannot. For example, it works with your body to produce and process what the body already knows how to do. Therefore, youre building on a procedure thats already in place. Taking HGH will allow you to do everything faster, including build muscle. Benefits include larger muscle gain, faster speeds, increased agility and an amazing ability to think and act quickly. Your overall performance will improve dramatically, and youll look good while youre doing it. Many people who use this product report that their hair, skin and nails become healthier and more attractive.

Safe and Legal Products

All of the products you buy here are safe, legal and effective. With this product, you will stimulate cell growth and muscle gain. You dont have to worry about the side effects that come with other types of products and there is no danger to your health from taking this. You wont have an increase in your blood pressure and your liver and kidneys will remain unexpected. Everything that happens to you with HGH is positive, including a stronger immune system and a better body inside and out.

If youve been curious about the human growth hormone but youve been unsure about trying it, now is a great time to experiment. Youll get results quickly, and that will tell you that its a positive change agent for your body. There is no need to hunt down a doctors prescription, and you dont need to stress out about needles and injections. You can take HGH orally, and the results will thrill you.

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Harnessing The Power Of HGH - Legal Steroids Here

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Sep 13th, 2018 | Filed under Human Growth Hormone