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Caryn M. Sullivan: Reflecting and regrouping during the pandemic – TwinCities.com-Pioneer Press

May 24th, 2020
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Way back in January, I decided this was going to be my best year ever. Resolving to be more deliberate about how and with whom I spent my time and resources, I set goals and made a plan.

Then the coronavirus arrived like a cyclone, claiming lives and upending our way of life. Suddenly, that plan felt indulgent and irrelevant.

The first few weeks of life as a shut-in were slow, surreal, and dark. It was as if loss and anxiety swept in, resurrecting old feelings of grief and paralyzing me in place. I was reminded that life is temporary, that some things are within our control and some are outside it.

Coronavirus has wrought grief on many levels. People are sharing in the COVID-19 experience in communities large and small, urban and remote. But our experiences are as individual as our DNA.

While folks on the front lines are dressed in masks and scrubs, those of us whose job is to stay at home are wearing yoga pants and slippers. Were Zooming, walking, doing our spring cleaning, and planting.

And were waiting.

Its springtime, but instead of box scores, were reading death counts in the newspaper.

Were inundated with in-the-trenches stories illuminating how professionals are fighting this disease and patients are surviving or succumbing to it.

With COVID-19 news 24/7, Ive fought the COVID blues more than once, for though its kept its distance from my loved ones and me, every reported death reminds us a family is grieving.

The death count is broadening as businesses also become casualties of the virus and resulting shutdown. When owners report theyve done everything they could, but they couldnt resuscitate their family restaurant, we grieve their loss and the loss of life as we knew it.

Its been a humbling journey, these past few months that feel more like a year.

When I first wrote about coronavirus in March, I was numb, ignorant, and optimistic. Anticipating the shutdown would be short-lived, I wrote about how we could rise to the pandemics evolving challenges.

In April, with reality setting in, I speculated about how we would approach re-entry when the Stay at Home order was lifted.

Will we pop champagne and race into the streets, or will we slowly re-emerge from our homes, like scuba divers trying to avoid the bends?

With both people and businesses gasping for air, the answer is revealing itself. Just as trees have flowered, light is creeping over the horizon.

Well mark Memorial Day without fanfare or public celebrations. Small gatherings will be allowed but BYOM (bring your own mask).

When we first sheltered in place, Minnesotans embraced social distancing directives. But over time, theres been a shift. Like a deflating balloon, the initial we can do this resolve has sputtered as days blurred into weeks and months.

Ive stretched to reconcile evolving and arguably arbitrary rules governing our behavior, while continuing to follow them.

Im not alone.

With higher temperatures and lower-than-projected deaths, a groundswell of anger and anxiety is percolating.

Businesses that closed on a dime are slowly re-opening. Theyre trying to resurrect their operations on a limited basis with measured steps. Formerly robust businesses may appear as if they were dieting as the rest of us were packing on our COVID 50.

Soon well regain the right to choose to get a haircut, eat at a different dining table, or continue to stay home.

While Im weary and wary, frustrated and impatient, my New Years resolve to be deliberate suddenly feels relevant.

Im begrudgingly accepting that to survive in a pandemic that continues to confound us, I must continue to surrender a bit of control over aspects of my life.

Just as we made adjustments after 9/11, well make accommodations in the way we go about life until we have effective treatments or a vaccine.

As we move forward, each of us will balance perceived risks against desired outcomes. Well make different decisions because we hold varying belief systems and risks from exposure to the virus.

Well do well to be mindful that as we exercise our free will, we might impact others through our choices and behavior.

Being deliberate in a COVID-19 world is not what I anticipated when I wrote my 2020 goals. But its helping me to create my own roadmap for moving forward with less anxiety.

Theres power in the how. Addressing how Im going to live with an invisible killer in our midst gives me an unexpected purpose and a renewed sense of optimism.

Im crafting a framework for intentionally shifting to living with an unwelcome intruder.

Im making hard choices about when, where, and how I will travel.

Im thinking about who will be in my close circle and who will stay a couple of arms lengths away.

Im evaluating wants versus needs.

Im thinking about how to optimize my time and talents.

Im making difficult decisions about how to best protect loved ones who have unique vulnerabilities.

At the core of the analysis lies one question. How will I weigh the various risks to live my best life in a COVID-19 world?

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Caryn M. Sullivan: Reflecting and regrouping during the pandemic - TwinCities.com-Pioneer Press

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Human Growth Hormone Market Size, Share, Trends and Forecast 2026 by Major Players and Business Opportunities Novo Nordisk, Pfizer, Eli Lilly – 3rd…

May 24th, 2020
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The report offers in-depth analysis of the global Human Growth Hormone market taking into account market dynamics, segmentation, geographical expansion, competitive landscape, and various other key aspects. The market analysts who have prepared the report have thoroughly studied the global Human Growth Hormone market and have offered reliable and accurate data. They understand the needs of the industry and the clients, which makes it easy for them to focus on the aspects, which the end users have been looking for.

Major Key Player Operating in this Report are: Novo Nordisk, Pfizer, Eli Lilly, Merck Serono, F. Hoffmann-La Roche, Ferring Pharmaceuticals, GeneScience Pharmaceuticals, Ipsen, LG Life Sciences, Sandoz International, Anhui Anke Biotechnology

Get the Sample of this [emailprotected]https://www.qyresearch.com/sample-form/form/1427700/global-human-growth-hormone-market

The report analyses the current trends, growth opportunities, competitive pricing, restraining factors, and boosters that may have an impact on the overall dynamics of the global Human Growth Hormone market. The report analytically studies the microeconomic and macroeconomic factors affecting the global Human Growth Hormone market growth. New and emerging technologies that may influence the global Human Growth Hormone market growth are also being studied in the report.

The market experts also offer best possible service and recommendations to the customers. This report can surely act as a resourceful tool for the companies, investors, and executives to become equipped and take sound and effective decisions. This will eventually help them stay ahead of the curve and gain maximum profits.

Segmental Analysis

The analysts have thoroughly studied all the segments including product type, application, and region. The report provides comprehensive analysis of the contribution of the segments to the overall market size. Moreover, the experts have predicted each segments growth potential, which may assist the clients to plan their future activities. The regional analysis mentioned in the report gives a clear cut understanding to the market participants regarding the present as well as future scenario of the global Human Growth Hormone market in key regions.

Segment By Type:

, Powder, Solvent

Segment By Application:

, Growth Hormone Deficiency (GHD), Turner Syndrome, Chronic Renal Insufficiency, Prader Willi Syndrome, Small for Gestational Age, SHOX Deficiency, Others Key Players: The Key manufacturers that are operating in the

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Human Growth Hormone industry. In order to fulfill the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Human Growth Hormone market include Novo Nordisk, Pfizer, Eli Lilly, Merck Serono, F. Hoffmann-La Roche, Ferring Pharmaceuticals, GeneScience Pharmaceuticals, Ipsen, LG Life Sciences, Sandoz International, Anhui Anke Biotechnology

Key queries related to the global Human Growth Hormone market addressed in the report:

While planning the strategic initiatives, market participants come across various questions and uncertainties. This report resolves various queries that most market players have regarding the global Human Growth Hormone market. Does the global Human Growth Hormone market have growth potential? What are the growth opportunities for the new entrants in the global Human Growth Hormone market? Who are the leading manufacturers operating in the global Human Growth Hormone market? Will they maintain their dominance in future? What are the key strategies that market players may adopt to strengthen their presence in the global Human Growth Hormone market? How will the competitive scenario undergo a change in years to come? What are the emerging trends that may influence the growth of the global Human Growth Hormone market? What are the factors that may hamper the global Human Growth Hormone market growth in the years ahead? Which product type segment is expected to exhibit promising growth in the near future? What application is anticipated to grab a major share in the global Human Growth Hormone market? Which region is likely to emerge as a lucrative regional market in the forthcoming years?

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Human Growth Hormone Market Table of Content

Table of Contents 1 Human Growth Hormone Market Overview1.1 Product Overview and Scope of Human Growth Hormone1.2 Human Growth Hormone Segment by Type1.2.1 Global Human Growth Hormone Sales Growth Rate Comparison by Type (2021-2026)1.2.2 Powder1.2.3 Solvent1.3 Human Growth Hormone Segment by Application1.3.1 Human Growth Hormone Sales Comparison by Application: 2020 VS 20261.3.2 Growth Hormone Deficiency (GHD)1.3.3 Turner Syndrome1.3.4 Chronic Renal Insufficiency1.3.5 Prader Willi Syndrome1.3.6 Small for Gestational Age1.3.7 SHOX Deficiency1.3.8 Others1.4 Global Human Growth Hormone Market Size Estimates and Forecasts1.4.1 Global Human Growth Hormone Revenue 2015-20261.4.2 Global Human Growth Hormone Sales 2015-20261.4.3 Human Growth Hormone Market Size by Region: 2020 Versus 2026 2 Global Human Growth Hormone Market Competition by Manufacturers2.1 Global Human Growth Hormone Sales Market Share by Manufacturers (2015-2020)2.2 Global Human Growth Hormone Revenue Share by Manufacturers (2015-2020)2.3 Global Human Growth Hormone Average Price by Manufacturers (2015-2020)2.4 Manufacturers Human Growth Hormone Manufacturing Sites, Area Served, Product Type2.5 Human Growth Hormone Market Competitive Situation and Trends2.5.1 Human Growth Hormone Market Concentration Rate2.5.2 Global Top 5 and Top 10 Players Market Share by Revenue2.5.3 Market Share by Company Type (Tier 1, Tier 2 and Tier 3)2.6 Manufacturers Mergers & Acquisitions, Expansion Plans2.7 Primary Interviews with Key Human Growth Hormone Players (Opinion Leaders) 3 Human Growth Hormone Retrospective Market Scenario by Region3.1 Global Human Growth Hormone Retrospective Market Scenario in Sales by Region: 2015-20203.2 Global Human Growth Hormone Retrospective Market Scenario in Revenue by Region: 2015-20203.3 North America Human Growth Hormone Market Facts & Figures by Country3.3.1 North America Human Growth Hormone Sales by Country3.3.2 North America Human Growth Hormone Sales by Country3.3.3 U.S.3.3.4 Canada3.4 Europe Human Growth Hormone Market Facts & Figures by Country3.4.1 Europe Human Growth Hormone Sales by Country3.4.2 Europe Human Growth Hormone Sales by Country3.4.3 Germany3.4.4 France3.4.5 U.K.3.4.6 Italy3.4.7 Russia3.5 Asia Pacific Human Growth Hormone Market Facts & Figures by Region3.5.1 Asia Pacific Human Growth Hormone Sales by Region3.5.2 Asia Pacific Human Growth Hormone Sales by Region3.5.3 China3.5.4 Japan3.5.5 South Korea3.5.6 India3.5.7 Australia3.5.8 Taiwan3.5.9 Indonesia3.5.10 Thailand3.5.11 Malaysia3.5.12 Philippines3.5.13 Vietnam3.6 Latin America Human Growth Hormone Market Facts & Figures by Country3.6.1 Latin America Human Growth Hormone Sales by Country3.6.2 Latin America Human Growth Hormone Sales by Country3.6.3 Mexico3.6.3 Brazil3.6.3 Argentina3.7 Middle East and Africa Human Growth Hormone Market Facts & Figures by Country3.7.1 Middle East and Africa Human Growth Hormone Sales by Country3.7.2 Middle East and Africa Human Growth Hormone Sales by Country3.7.3 Turkey3.7.4 Saudi Arabia3.7.5 U.A.E 4 Global Human Growth Hormone Historic Market Analysis by Type4.1 Global Human Growth Hormone Sales Market Share by Type (2015-2020)4.2 Global Human Growth Hormone Revenue Market Share by Type (2015-2020)4.3 Global Human Growth Hormone Price Market Share by Type (2015-2020)4.4 Global Human Growth Hormone Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End 5 Global Human Growth Hormone Historic Market Analysis by Application5.1 Global Human Growth Hormone Sales Market Share by Application (2015-2020)5.2 Global Human Growth Hormone Revenue Market Share by Application (2015-2020)5.3 Global Human Growth Hormone Price by Application (2015-2020) 6 Company Profiles and Key Figures in Human Growth Hormone Business6.1 Novo Nordisk6.1.1 Corporation Information6.1.2 Novo Nordisk Description, Business Overview and Total Revenue6.1.3 Novo Nordisk Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.1.4 Novo Nordisk Products Offered6.1.5 Novo Nordisk Recent Development6.2 Pfizer6.2.1 Pfizer Human Growth Hormone Production Sites and Area Served6.2.2 Pfizer Description, Business Overview and Total Revenue6.2.3 Pfizer Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.2.4 Pfizer Products Offered6.2.5 Pfizer Recent Development6.3 Eli Lilly6.3.1 Eli Lilly Human Growth Hormone Production Sites and Area Served6.3.2 Eli Lilly Description, Business Overview and Total Revenue6.3.3 Eli Lilly Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.3.4 Eli Lilly Products Offered6.3.5 Eli Lilly Recent Development6.4 Merck Serono6.4.1 Merck Serono Human Growth Hormone Production Sites and Area Served6.4.2 Merck Serono Description, Business Overview and Total Revenue6.4.3 Merck Serono Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.4.4 Merck Serono Products Offered6.4.5 Merck Serono Recent Development6.5 F. Hoffmann-La Roche6.5.1 F. Hoffmann-La Roche Human Growth Hormone Production Sites and Area Served6.5.2 F. Hoffmann-La Roche Description, Business Overview and Total Revenue6.5.3 F. Hoffmann-La Roche Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.5.4 F. Hoffmann-La Roche Products Offered6.5.5 F. Hoffmann-La Roche Recent Development6.6 Ferring Pharmaceuticals6.6.1 Ferring Pharmaceuticals Human Growth Hormone Production Sites and Area Served6.6.2 Ferring Pharmaceuticals Description, Business Overview and Total Revenue6.6.3 Ferring Pharmaceuticals Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.6.4 Ferring Pharmaceuticals Products Offered6.6.5 Ferring Pharmaceuticals Recent Development6.7 GeneScience Pharmaceuticals6.6.1 GeneScience Pharmaceuticals Human Growth Hormone Production Sites and Area Served6.6.2 GeneScience Pharmaceuticals Description, Business Overview and Total Revenue6.6.3 GeneScience Pharmaceuticals Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.4.4 GeneScience Pharmaceuticals Products Offered6.7.5 GeneScience Pharmaceuticals Recent Development6.8 Ipsen6.8.1 Ipsen Human Growth Hormone Production Sites and Area Served6.8.2 Ipsen Description, Business Overview and Total Revenue6.8.3 Ipsen Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.8.4 Ipsen Products Offered6.8.5 Ipsen Recent Development6.9 LG Life Sciences6.9.1 LG Life Sciences Human Growth Hormone Production Sites and Area Served6.9.2 LG Life Sciences Description, Business Overview and Total Revenue6.9.3 LG Life Sciences Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.9.4 LG Life Sciences Products Offered6.9.5 LG Life Sciences Recent Development6.10 Sandoz International6.10.1 Sandoz International Human Growth Hormone Production Sites and Area Served6.10.2 Sandoz International Description, Business Overview and Total Revenue6.10.3 Sandoz International Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.10.4 Sandoz International Products Offered6.10.5 Sandoz International Recent Development6.11 Anhui Anke Biotechnology6.11.1 Anhui Anke Biotechnology Human Growth Hormone Production Sites and Area Served6.11.2 Anhui Anke Biotechnology Human Growth Hormone Description, Business Overview and Total Revenue6.11.3 Anhui Anke Biotechnology Human Growth Hormone Sales, Revenue and Gross Margin (2015-2020)6.11.4 Anhui Anke Biotechnology Products Offered6.11.5 Anhui Anke Biotechnology Recent Development 7 Human Growth Hormone Manufacturing Cost Analysis7.1 Human Growth Hormone Key Raw Materials Analysis7.1.1 Key Raw Materials7.1.2 Key Raw Materials Price Trend7.1.3 Key Suppliers of Raw Materials7.2 Proportion of Manufacturing Cost Structure7.3 Manufacturing Process Analysis of Human Growth Hormone7.4 Human Growth Hormone Industrial Chain Analysis 8 Marketing Channel, Distributors and Customers8.1 Marketing Channel8.2 Human Growth Hormone Distributors List8.3 Human Growth Hormone Customers 9 Market Dynamics 9.1 Market Trends 9.2 Opportunities and Drivers 9.3 Challenges 9.4 Porters Five Forces Analysis 10 Global Market Forecast10.1 Global Human Growth Hormone Market Estimates and Projections by Type10.1.1 Global Forecasted Sales of Human Growth Hormone by Type (2021-2026)10.1.2 Global Forecasted Revenue of Human Growth Hormone by Type (2021-2026)10.2 Human Growth Hormone Market Estimates and Projections by Application10.2.1 Global Forecasted Sales of Human Growth Hormone by Application (2021-2026)10.2.2 Global Forecasted Revenue of Human Growth Hormone by Application (2021-2026)10.3 Human Growth Hormone Market Estimates and Projections by Region10.3.1 Global Forecasted Sales of Human Growth Hormone by Region (2021-2026)10.3.2 Global Forecasted Revenue of Human Growth Hormone by Region (2021-2026)10.4 North America Human Growth Hormone Estimates and Projections (2021-2026)10.5 Europe Human Growth Hormone Estimates and Projections (2021-2026)10.6 Asia Pacific Human Growth Hormone Estimates and Projections (2021-2026)10.7 Latin America Human Growth Hormone Estimates and Projections (2021-2026)10.8 Middle East and Africa Human Growth Hormone Estimates and Projections (2021-2026) 11 Research Finding and Conclusion 12 Methodology and Data Source 12.1 Methodology/Research Approach 12.1.1 Research Programs/Design 12.1.2 Market Size Estimation 12.1.3 Market Breakdown and Data Triangulation 12.2 Data Source 12.2.1 Secondary Sources 12.2.2 Primary Sources 12.3 Author List 12.4 DisclaimerAbout Us:QYResearch always pursuits high product quality with the belief that quality is the soul of business. Through years of effort and supports from huge number of customer supports, QYResearch consulting group has accumulated creative design methods on many high-quality markets investigation and research team with rich experience. Today, QYResearch has become the brand of quality assurance in consulting industry.

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Human Growth Hormone Market Size, Share, Trends and Forecast 2026 by Major Players and Business Opportunities Novo Nordisk, Pfizer, Eli Lilly - 3rd...

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Lance Armstrong documentary: The characters you’ll want to know – ESPN

May 24th, 2020
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ESPN's 30 for 30 "LANCE," directed by Marina ZenovichPart 1: 9 p.m. ET Sunday on ESPNPart 2: 9 p.m. ET May 31 on ESPNLive streaming: ESPN App, ESPN+

For perhaps the first time, Lance Armstrong, his family and his former teammates talk candidly about his seven Tour de France victories -- and the events before and after he was exposed in one of the largest doping scandals in sports history.

Which characters in "LANCE" should you know to fully understand the complicated story? We've got you covered:

Perhaps the most infamous of Armstrong's former teammates, Landis was recruited by Armstrong to the U.S. Postal Service team in 2002, and he helped him win three of his seven Tour de France victories. After Armstrong retired, Landis won the Tour in 2006 while competing for a Swiss cycling team named Phonak, then tested positive for testosterone immediately afterward. He served a two-year suspension and was stripped of his title, but when he attempted to return to the sport, Armstrong and others denied him spots on their teams. Landis said he felt betrayed -- as if he had taken the fall for all of them -- and in 2010, sent emails to USA Cycling CEO Steve Johnson and other high-ranking cycling and anti-doping officials, with details on the doping incidences he had seen from Armstrong and other prominent cyclists. This was the beginning of Armstrong's public downfall.

The former soigneur for the USPS team, O'Reilly provided physical therapy, massage therapy and other help for the team. She is widely considered to be the first whistleblower and gave an interview in 2003 to journalist David Walsh, saying that Armstrong asked her to dispose of used syringes and hide needle marks with makeup. Armstrong fought back, suing her for libel and calling her vicious names. Armstrong calls his treatment of her "the worst thing he's ever done" in his life. O'Reilly, for her part, said she has since forgiven Armstrong and considers him a friend again.

Hamilton helped Armstrong win three Tours, then parted ways with the USPS team in 2001 because he wanted a shot to compete on his own. Hamilton describes himself as friends with Armstrong when they were teammates, then no longer friendly once Hamilton left the team. Hamilton said that after he beat Armstrong in a time trial in 2004, Armstrong called the UCI and directed the organization to investigate Hamilton for doping. Hamilton later tested positive for banned substances after winning the 2004 Olympic individual time trial and the Vuelta a Espana, and after serving a two-year suspension, failed another drug test in 2009. He was later stripped of his Olympic gold medal, and he testified on multiple occasions that he had seen Armstrong doping.

Frankie Andreu was team captain of the USPS team from 1998 until 2000. Frankie and his wife, Betsy, testified in 2005 that while Armstrong was receiving cancer treatment in 1996, he told doctors in their presence that he had taken erythropoietin (EPO), testosterone, human growth hormone, steroids and cortisone. They later gave damning affidavits to the U.S. Anti-Doping Agency (USADA) in 2012 that reiterated that account and included additional detailed incidences of Armstrong doping.

Hincapie competed on the USPS team from 1997 to 2007 and, like Frankie Andreu, admitted to doping and testified against Armstrong in the 2012 USADA decision. Hincapie had tied the record of completed Tours, at 16, before he was retroactively disqualified from the 2004-2006 Tours after the admission. He and Armstrong consider themselves friends today, however.

An Italian cycling coach and doctor, Ferrari was well-known in cycling circles for his doping practices. Armstrong had worked with him periodically for six years when, in 2004, Ferrari was sentenced to a 12-month suspended jail sentence for malpractice. He was later acquitted of the charges, but in 2012 he received a lifetime ban from USADA for doping violations.

A former three-time Tour winner in 1986, 1989 and 1990, LeMond was an inspiration to Armstrong as he switched from competing in triathlons to cycling. After Armstrong's third Tour victory in 2001, LeMond publicly expressed disappointment that Armstrong was working with Dr. Ferrari and famously said, "If Lance is clean, it is the greatest comeback in the history of sport. If he isn't, it would be the greatest fraud." LeMond alleges Armstrong then used his influence with their mutual sponsor, Trek, to ruin LeMond's business. Since Armstrong and Landis have been stripped of their Tour de France titles, LeMond is currently the only American winner of the event.

Once a superstar in his home country of Germany, Ullrich won the 1997 Tour, and then he was the perennial second-place finisher to Armstrong in the early 2000s. At the 2006 Tour after Armstrong retired, Ullrich was considered one of the favorites, until he was implicated in an investigation into blood doping. He was barred from the Tour that year and never raced professionally again. After incidents involving drunk driving, a break-in and assault, in 2018 he was admitted to a psychiatric hospital. Armstrong went to visit him, saying, "I love Jan Ullrich. He was such a special rival to me. He scared me, he motivated me, and truly brought out the best in me."

Armstrong was raised by his mother, Linda Armstrong Kelly, who gave birth to him in 1971 when she was 17. His biological father, Eddie Gunderson, was briefly married to Linda, but it was an abusive relationship and ended when Lance was 2. A year later, Linda married Terry Armstrong, and he formally adopted Lance. The couple later divorced when Lance was 15.

Lance Armstrong married Kristin Richard in 1998, and the couple had three children: Luke, Isabelle and Grace. They divorced in 2003. Armstrong met fiance Anna Hansen in 2008, and the couple have since had two children, Max and Olivia.

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Lance Armstrong documentary: The characters you'll want to know - ESPN

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5 things we learned from ‘Modern Family’ oral history about Sarah Hyland, Sofia Vergara and Fred Willard – USA TODAY

May 24th, 2020
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Known for playing Alex and Luke Dunphy on ABC's "Modern Family," Ariel Winter and Nolan Gould talk growing up before the fans' eyes over the decade. USA TODAY

"Modern Family" was on the air for 11 years, so you better believe that pretend family has some real memories from their time on set.

Marc Freeman's "Modern Family: The Untold Oral History of One of Television's Groundbreaking Sitcoms" (St. Martin's Press,528 pp.) explores the making of the ABC show, which used the mockumentary format to bring to light new stories about what families really looked like.

The oral history includes new interviews with the stars, creators, crew and some famous faces who were in the running to be cast. Freeman also included commentary and observationsfrom his time spent on set in February during the last few days of the series' filming.

"We were a show that was able to bring people together," Sofia Vergara (Gloria) said to him. "One of the most fascinating things for me was meeting people, a grandmother with a grandchild, talking about the same episode. That rarely happens. Men would watch, gay people would watch. I think that's what made it so special. I don't think there are that many shows written that can bring the whole family together.

Here are 5 of the most interesting things we learned:

"Modern Family: The Untold Oral History of One of Televisions Groundbreaking Sitcoms" by Marc Freeman hits bookshelves May 19.(Photo: Courtesy St. Martin's Press)

Most of the main character roles got at least a thousand audition submissions before the creators settled on the actors "Modern Family" fans know today. Though a handful of famous faces ended up in the mix, some other big stars were considered or in the running for roles.

In the early days of "Modern Family," plenty of ideas were tossed around about how to tell the stories of, well, modern families. Creators considered making it about three families living on a cul-de-sac, or just separate households that went through similar weekly struggles. The idea of three households in the same family ultimately won.

But not every idea after that was a winner. These story lines got pitched but never made it to air:

Cast members in 2009, from left to right: Ed O'Neill, Rico Rodriguez, Sofia Vergara, Nolan Gould, Julie Bowen, Ariel Winter, Ty Burrell, Sarah Hyland, Jesse Tyler Ferguson and Eric Stonestreet.(Photo: BOB D'AMICO, ABC)

Hyland, 29, has been open on her social media accounts about struggling with kidney dysplasia and endometriosis. Though there were plenty of times on set when she wasn't feeling well the actress noted that she would often choose for Haley to lean against a wall or table in a scene because standing up straight was too painfulshe impressed her co-workers with the way she powered through.

"There were lots of days when she'd be in the makeup chair in the morning and you could see she wasn't feeling good," O'Neill said. "And you felt so bad. You'd think, 'Can you do anything, say anything, bring her anything?' But she was there. She showed up, all the time, unless she was in the hospital."

Winter, 22, struggled with negativityonline she "developed much earlier than a lot of other girls," and commentary on her body has continued since then.

"It happens to all people in the public eye," Winter said. "But when you're a child, it's worse because you're trying to figure out who you are, trying to navigate the world with everybody else trying to navigate it for you."

The Dunphy trio was all grown up by the series finale.(Photo: Eric McCandless, ABC)

Gould, 21, has been decidedly less vocal about his personal life, aided in part by watching the way his two on-screen sisters were treated on social media over the years. He revealed to Freeman he had a human growth hormone deficiency while growing up on camera.

"I ended up having to give myself human growth hormones," he said. "That's one of the reasons you'll notice there's this one season where I go from a baby to a weird man-child with a deep voice and facial hair."

Fred Willard appears in an episode of 'Modern Family' in 2009.(Photo: Adam Taylor, Walt Disney Television via Getty Images)

"Modern Family" characters said goodbye to comedy great Fred Willard's character, Frank Dunphy, in Season 11. Losing a character in the final seasonrepresented the cast's first of several goodbyes for the longtime co-workers. And now, the book debuts less than a weekafter Willard died at 86, making it a fitting tribute to the late actor as well.

"The scene where Phil offers a toast to his dad was very moving," Freeman writes. "Ty shed a tear, and it was impossible for everyone else not to at that point. Yes, we were saying goodbye to Frank, but there was also a harbinger of the end of the series in there, too. We will be saying goodbye to each other all too soon."

Co-creator Steven Levitan told Freeman of the actor:"Willard will never stop being one of the most brilliant improvisational comedians of our or any other generation's list."

'Thanks for the deep belly laughs': Jesse Tyler Ferguson, Sofia Vergara mourn Fred Willard's death

Each house was decorated to make it appear as though the characters really lived there: Photos were hung on the walls and updated over the years (designers would later add candid shots from travel and graduation episodes). And just like in real homes, the actors playing the Dunphy kids marked their growth over the years on the kitchen set.

"When the kids were on set, they would mark their heights as they grew season to season," production designer and art director Claire Bennett said. "It's a nice touch that will never make it to camera."

'Modern Family' cast on long run: 'People connected in a that's-really-what-it's-like way'

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Adele Shows Off Her Weight Loss In Elzinga – Celebrity Insider

May 24th, 2020
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By now, everyone has seen the new photo of Adele showing off her stunning weight loss. People have compared her to actress Sarah Paulson and there have been debates over how we judge beauty and what it means when people lavish praise on someone after they lose weight. Adele celebrated her 32nd birthday on May 5, 2020, and she showed off her new, thinner frame by posting a photo of herself wearing Elzinga. The dress quickly sold out and demand for the dress continues to increase.

Elzinga posted the photo of Adele in the dress on their official Instagram page along with the following caption.

Adele in the balloon-sleeve silk-organza mini dress on her birthday!Happy birthday Adele!#adele #elzinga #birthday

The dress retails for approximately $610 and until Elzinga has enough to satisfy their customers, look-a-like dresses are also selling out.

You may see the post that Adele shared where she showcased her new figure in the Elzinga dress below.

https://www.instagram.com/p/B_2cs6lF3rN/

It is believed that Adele lost approximately 100 pounds and even though there are social distancing rules in place, she has been able to continue working out and maintain her new figure. Many gyms are beginning to reopen as long as people stay a good six feet apart and Adele has made significant changes in her life.

She switched her diet to one that is mainly plant-based and has ditched sugary, calorie-laden, and junk foods. Adele is reportedly following the SIRTfood diet that involves eating foods that contain a specific protein and restricting calories to about 1000 per day in addition to regular exercise.

Adele lost weight quickly and effectively, but it is likely if she changes her diet she would begin to gain weight again. Regardless, everyone agrees that Adele looks sensational and the fact that the Elzinga Studios dress sold out immediately after Adele posted her photo is a testament to her star power.

What do you think about Adele in Elzinga? Are you a fan of the dress?

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Charisse Van Horn is a freelance writer from Tampa Bay. She enjoys writing about celebrities, entertainment, and fashion. Any reproduction of this article outside of Celebrity Insider will be met with legal action by the writer.

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What To Buy Someone Whos Gone Keto – IMC Grupo

May 24th, 2020
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In thehealth and wellness world, we are bombarded by so many trendy diets that it canbe difficult trying to keep up with it all, let alone how or if they work. Ifyou know a yo-yo dieter, it can also be quite challenging trying to keep trackof their meal plans and workouts, which can make gift buying an absolutenightmare.

If you arelooking for a gift for someone that is transitioning or has transitioned to theketo diet, youre in luck. Unlike most other diets out there (were looking atyou Dukan diet), the Keto diet has been around for years. As such, it is one ofthose diets that boast staying power.

The Ketodiet may sound like one of those buzzwords that you hear circulating online.However, you should know that it is one of the most popular and vastlyresearched diets. It is so popular that even celebrities like Halle Berry swearby it.

Keto isshort forKetogenic diet, which is all about encouraging theminimization of carbs and upping healthy fat intake. The point of increasingyour fat intake is so that your body can get used to utilizing fat as an energysource instead of relying on carbs.

Becauseyou dont get to eat carbohydrate loaded foods when you are on the keto diet,you instead load up on healthy fats such as olive oil and avocado alongsidelean proteins such as beef and chicken. Fruits, greens, and all othernon-starchy veggies are also part of the diet.

If youhave a friend that is transitioning to the Keto diet, any support that youprovide can go a long way in ensuring that they are successful. And because theKeto diet is one of those diets that has endured the test of time (andInstagram hashtags), there are plenty of great products out there to consider.

For yourspecial someone to ace this diet, they will need to first ensure that they arein a state of ketosis. And ketosis doesnt just occur-once someone goes on aketo diet, it takes a few days (about 3 days for most individuals) to get intoketosis.

The onlyway to find out if one has reached the ketosis state is to monitor ones ketonelevels in the body using a blood ketone meter. There are several great optionsout there in the market so you shouldnt have trouble finding the right one foryour budget.

Electrolytebalance is one of the most essential yet frequently overlooked components ofsucceeding on a keto diet. When you are on a low carb diet such as the oneencouraged by the keto diet, you effectively strip your body of itselectrolytes due to the loss of body fluids.

When thebody runs low on electrolytes, it causes brain fog, low energy, and a hostofother issuessuch as headaches that shouldbe avoided particularly during the early stages of joining the keto diet.

The moststraightforward way to prevent this electrolyte shortage in the body is tosupport ones diet by adding essential electrolytes such as magnesium, sodium,and calcium. The electrolytes will preserve the bodys natural balance as wellas ensure that your loved one is performing optimally throughout.

Avocado istruly a keto dieters best friend, no joke! Avocados are the perfect food forany keto dieter. Not only are avocados loaded with healthy monounsaturatedfats, which is exactly what a person in a keto diet needs, but the extra fatprovided by an avocado is crucial for speeding up the fat-adaptation processduring those early days of starting the ketogenic diet.

Avocadosare high in fiber, are choke-full of vitamins and minerals, and are great forstabilizing ones blood sugar. But we all know that avocados arent exactly theeasiest fruits to deal with. Because they are naturally oily and slippery,cutting an avocado can be a dangerous affair but not if your special someonehas a handyavocado slicerto make things easier.

If yourloved one has been using that old water bottle they have had for years, maketheir day with a smart water bottle. Not only are smart water bottles betterdesigned than those horrible plastic bottles, but they are also durable,capable of withstanding any trips to the gym.

Thesearent just your mamas water bottle; smart water bottlesare on another level. Most contain smart lids that areembedded with sensors that notify the user how much water they have consumed,as well as the temperature of the water being consumed.

Most smartbottles are easy to control through the bottles designated app. However,others have a built-in display that provides the user with real-timeinformation. Drinking water regularly is a vital aspect of livinghealthily.

However,when you are on the keto diet, water is all the more important because itimproves ones fat metabolism. If your special someone fails to monitor theirwater intake carefully while on the diet, dehydration could occur, which willlead to headaches and overall fatigue.

If thisoccurs, it can deter them from getting the results they are after and it couldalso lead to long term problems, which is the last thing anyone wants whentheyre trying to live a healthier lifestyle.

Even if youdont care about the keto diet, it is important to support your friends andloved ones when they are trying something new to make them healthier. Decidingto live a healthier lifestyle is a big deal.

Show thatyou recognize how important this decision is by gifting your loved one withsomething that can help them achieve their goals. Go above and beyond with thegifts listed above for that loved one that just wont shut up about the ketodiet.

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What Is The Connection Between Diabetes And Thirst? – South Florida Reporter

May 24th, 2020
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What is excessive thirst?

Age, lifestyle, and activity levels can contribute to how much a person drinks.

According to theCenters for Disease Control and Prevention (CDC), there are currently no guidelines about how much water a person should drink each day.

In 2004, theInstitute of Medicineestimated an adequate daily water intake as 3.7 liters for males and 2.7 liters for females. These amounts included water from all the drinks and foods in a persons diet.

According to theNational Health and Nutrition Examination Survey, 20092012, males in the United States tend to consume 3.46 liters of water per day, while females in the country typically consume 2.74 liters per day. These figures also included water from all dietary sources.

However, from day to day, a person may feel more or less thirsty for a variety of reasons. Spending time in the sun or being especially active, for example, can contribute to thirst.

Diabetes that causes excessive thirst

Different types of diabetes can cause excessive thirst.

The term diabetes mellitusincludesdiabetes types 1 and 2.

A person withtype 1 diabetesis unable to produceinsulin.

Someone withtype 2 diabetesis able to produce insulin, but their body is unable to use it effectively to help glucose enter cells.

In either case, glucose from digested food remains in the bloodstream.

As the authors of a2014 articlenote, the kidneys excrete some excess glucose through urine. As the glucose draws water into the urine, the body loses more fluid than it should. This results in the person becoming extra thirsty.

Gestational diabetesoccurs during pregnancy.

Just as in a person with diabetes mellitus, in a woman with gestational diabetes,insulin resistancecanlead tohyperglycemia.

For the reasons that we describe in the section above, this can lead to an increased need to urinate and excessive thirst.

Diabetes insipidusis arare conditionthat involves the kidneys passing an unusually high amount of urine, which is diluted and odorless.

Typically, the kidneys pass about12 quartsof urine a day. In someone with diabetes insipidus, the kidneys can pass320 quartsa day. This results in the person being excessively thirsty.

Unlike a person with diabetes mellitus, someone with diabetes insipidus hasnormalblood glucose levels. However, their kidneys are unable to balance the amount of fluid in the body.

This can happen for a number of reasons, including:

The factors above can disrupt the function of the hormone vasopressin. This hormone works with the brain and kidneys to help regulate fluids in the body.

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Add some muscle: How to avoid being hamstrung by your supply chain the next time a crisis hits – Supply Chain Digital – The Procurement & Supply…

May 24th, 2020
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The very nature of supply chains the movement of goods and services means its unsurprising they have been seriously disrupted by the global COVID-19 pandemic. With several areas in lockdown, borders shut, and businesses ordered to temporarily close by governments, many organisations have been thrown into chaos. Weve seen UK manufacturers suddenly halting production after having the flow of parts into factories cut off, while (non-grocery) retailers have taken a range of actions from shutting stores and ramping up online operations to cancelling orders altogether.

Lean, or frail?

So why have the businesses that can trade through the crisis found it particularly challenging? Besides the panic buying thats made it very difficult to predict demand, according to Warwick University Manufacturing Group research, businesses have been focused on trying to improve visibility across their supply chains and using that to predict potential future demand and supply. They have not progressed beyond this to what the research labels stage three and four sophistication by which point they would become prescriptive, self-learning and autonomous.

Before the crisis hit, sustained economic growth meant businesses were focussed on making their supply chains as lean as possible, so they could provide goods quickly and cost-effectively. One might argue that rather than being lean, supply chains had accidentally become frail they were simply not prepared to react to disruption. As McKinsey notes, its impossible to foresee unknown risks whether theyre natural, such as a volcanic eruption near a factory, or man-made, for example if a supplier goes out of business. No crystal ball exists that will allow businesses to predict these kinds of events, so they must put their supply chains in a better position to react when they happen.

A strategy for getting supply chains into shape

Just as many people are re-evaluating their diet and exercise regimes so they can get into good shape while on lockdown, businesses need to find ways to make their supply chains stronger and more resilient too. Firstly, they should review their overall strategy for sourcing items. As a case in point, since the crisis hit, the manufacturing industrys reliance on parts solely produced in APAC has led to considerable disruption. By developing additional sources closer to home, potential issues can be reduced helping retailers avoid risks like items being delayed while in transit, or factories being placed under restrictions or lockdowns that are not immediately obvious to European businesses.

Using technology for 20/20 vision

Supply chain management technology can also play a crucial role; if businesses cannot keep track of everything that is happening, how can they even begin to react when they hit disruption? This is where control towers can be deployed to give visibility over all activity, offering a visual representation that makes it possible to fully comprehend the status of all moving parts. This viewpoint makes it a more realistic prospect to identify problems as they are beginning to unfold, and to figure out how to resolve them.

Once full visibility over activity has been achieved, businesses can also use Artificial Intelligence (AI) and Machine Learning (ML) to read what is going on and recommend how to fix problems. In time, AI/ML systems could even put those changes into place without input from humans, to form an autonomous supply chain. AI can also start to predict disruptions and then, autonomously prevent or avoid them.

Building the muscles

The COVID-19 pandemic has forced many businesses to sit up and realise that their supply chains have gone beyond being lean, and have instead become frail. Once the chaos began and continues to unfold, it became clear that too many businesses relied heavily on suppliers that were single-source and based halfway around the world.

Nows the time to learn from this mistake and build up better visibility and a higher level of risk-awareness. Businesses must focus on building up the muscles of a strong supply chain by using strategies that give them more options, while employing technology to provide extra insight and guidance. If they can do this, businesses will emerge with a stronger supply chain, putting them in a much greater position to deal with disruption in the future.

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Blue Light and Sleep: What’s the Connection? – EcoWatch

May 24th, 2020
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By Kris Gunnars, BSc

Sleep is one of the pillars of optimal health.

However, people are sleeping much less than they did in the past. Sleep quality has also declined.

Poor sleep is linked to heart disease, type 2 diabetes, depression, and obesity.

The use of artificial lighting and electronics at night may contribute to sleep problems. These devices emit light of a blue wavelength, which may trick your brain into thinking it's daytime.

Many studies suggest that blue light in the evening disrupts your brain's natural sleep-wake cycles, which are crucial for optimal health.

This article explains how blocking blue light at night can aid your sleep.

Your body has an internal clock that regulates your circadian rhythm the 24-hour biological cycle that influences many internal functions.

Most importantly, it determines when your body is primed for being awake or asleep.

However, your circadian rhythm needs signals from the external environment most importantly daylight and darkness to adjust itself.

Blue-wavelength light stimulates sensors in your eyes to send signals to your brain's internal clock.

Keep in mind that sunlight and white light contain a mixture of various wavelengths, each of which has a significant amount of blue light.

Getting blue light, especially from the sun, in the daytime helps you stay alert while improving performance and mood.

Blue light therapy devices may help treat depression, and blue light bulbs have been shown to reduce fatigue and improve the mood, performance, and sleep of office workers.

Yet, modern light bulbs and electronic devices, especially computer monitors, likewise produce large amounts of blue light and may disrupt your internal clock if you're exposed to them during the evening.

When it gets dark, your pineal gland secretes the hormone melatonin, which tells your body to get tired and go to sleep.

Blue light, whether from the sun or a laptop, is very effective at inhibiting melatonin production thus reducing both the quantity and quality of your sleep.

Studies link melatonin suppression in the evening to various health problems, including metabolic syndrome, obesity, cancer, and depression.

Summary

Blue light in the evening tricks your brain into thinking it's daytime, which inhibits the production of melatonin and reduces both the quantity and quality of your sleep.

Amber-tinted glasses offer the easiest and most effective way to avoid blue light exposure at night.

These glasses effectively block all blue light. Thus, your brain doesn't get the signal that it's supposed to stay awake.

Studies show that when people use blue-light-blocking glasses, even in a lit room or while using an electronic device, they produce just as much melatonin as if it were dark.

In one study, people's melatonin levels in the evening were compared across dim light, bright light, and bright light with tinted glasses.

The bright light almost completely suppressed melatonin production, while the dim light did not.

Notably, those wearing the glasses produced the same amount of melatonin as those exposed to dim light. The glasses largely canceled out the melatonin-suppressing effect of the bright light.

Likewise, blue-light-blocking glasses have been shown to spur major improvements in sleep and mental performance.

In one 2-week study, 20 individuals used either blue-light-blocking glasses or glasses that didn't block blue light for 3 hours before bedtime. The former group experienced major improvements in both sleep quality and mood.

These glasses have also been found to greatly improve sleep in shift workers when worn before bedtime.

What's more, in a study in older adults with cataracts, blue-light-blocking lenses improved sleep and significantly reduced daytime dysfunction.

That said, not all studies support the use of blue-light-blocking lenses or glasses. One analysis of several studies concluded that there's a lack of high quality evidence supporting their use.

Nevertheless, blue-light-blocking glasses may provide some benefits.

Shop blue-light-blocking glasses online.

Summary

Some studies suggest that blue-light-blocking glasses may increase melatonin production during the evening, leading to major improvements in sleep and mood.

If you don't want to use glasses every night, there are a few other ways to reduce blue light exposure.

One popular way is to install a program called f.lux on your computer.

This program automatically adjusts the color and brightness of your screen based on your timezone. When it's dark outside, it effectively blocks all blue light and gives your monitor a faint orange hue.

Similar apps are available for your smartphone.

A few other tips include:

It's also important to expose yourself to plenty of blue light during the day.

If you can, go outside to get sunlight exposure. Otherwise, consider a blue light therapy device a strong lamp that simulates the sun and bathes your face and eyes in blue light.

Summary

Other ways to block blue light in the evening include dimming or turning off the lights in your home and installing an app that adjusts the light your laptop and smartphone emit.

Blue light, which is emitted from smartphones, computers, and bright lights, may inhibit your sleep if you're exposed to it at night.

If you have a history of sleeping problems, try reducing your exposure to blue light during the evenings.

Amber-tinted glasses may be particularly effective.

Several studies support their ability to improve sleep quality.

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The Changing Profile of Liver Disease – Physician’s Weekly

May 24th, 2020
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With significant advances in the treatment of viral hepatitisincluding increasing cure rates for hepatitis C and highly effective treatment of hepatitis Bsuspicions have arisen that the profile of liver disease in the United States will change, explains Zobair M. Younossi MD, MPH. The liver disease associated with obesity and diabetes is non-alcoholic fatty liver disease (NAFLD), and thus it has been hypothesized that, as viral hepatitis B and C are being treated more effectively and the rates of obesity are increasing, and the fact also that there is no treatment for NAFLD, that rates of NAFLD will increase, he adds. Given this, its important for to understand the type of liver disease burden to expect over the next few decades.

Confirming Suspicions

To assess the shift in the prevalence of different live disease etiologies (chronic hepatitis B, hepatitis C, alcoholic liver disease, and NAFLD) over the past 3 decades, Dr. Younossi and colleagues assessed prevalence data among more than 58,000 NHANES participants during 1988-1994, 1999-2004, 2009-2012, and 2013-2016. Their results were published in Gut.

We found that, over these time periods, the only liver disease that increased in prevalence was NAFLD, from 20% in 1998-1994 to 32% in 2013-2016 (Figure), says Dr. Younossi. The prevalence of hepatitis C actually decreased over time, while the prevalence rates of hepatitis B and alcoholic liver disease remained stable. During the same period, steady increases were observed in rates of obesity (from 22.2% to 38.9%), type 2 diabetes (from 7.2% to 13.5%), insulin resistance, and hypertension.

When we assessed the drivers of increasing NAFLD prevalence by running a multivariable regression analysis and controlling for all potential confounders, it was clearly shown that obesity and type 2 diabetes were two major, independent predictors of NAFLD, notes Dr. Younossi. We think, and believe its been confirmed, that the rates of increase in obesity and type 2 diabetes lead to another complication, and thats an increasing rate of NAFLD.

Important Considerations

Dr. Younossi explains that there are important factors associated with the increased prevalence of NAFLD for physicians to consider, among them that the disease may be more prevalence in Hispanic Americans, when compared with Caucasians and African Americans. Also, although obesity and type 2 diabetes are the strongest drivers of NAFLD, other metabolic conditions play a role, specifically high cholesterol and high blood pressure. These four conditionsobesity, type 2 diabetes, high cholesterol, and hypertension pressuremake up metabolic syndrome, of which NALFD is a liver complication.

Because of the prevalence of NAFLD and potential for encountering a patient with the disease, Dr. Younossi recommends that primary care physicians, cardiologists, endocrinologists, gastroenterologists, and other specialists understand that NAFLD is going to become the most common liver disease in the US, as well as that some patients with NAFLD will have non-alcoholic steatohepatitis (NASH) and can potentially progress to cirrhosis. In fact, NASH is now one of the most common indications for liver transplantation, especially in women, an important cause of liver cancer, and negatively impact quality of life and other patient-reported outcomes.

Dr. Younossi notes the need for more research to better understand which patients with NAFLD will progress to NASH. Its important to have an accurate, noninvasive test, because NASH is currently diagnosed via liver biopsy, he adds. We also need better treatment; we currently only have lifestyle modification with exercise and diet. With medical treatment becoming available in the future, knowing exactly which patients should be treated with the addition of medication versus only lifestyle modification is something were looking forward to. In the meantime, Dr. Younossi calls for increased awareness among physicians of NAFLD as an important complication of metabolic syndrome.

Epidemiology of chronic liver diseases in the USA in the past three decadeshttps://gut.bmj.com/content/early/2019/07/30/gutjnl-2019-318813

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