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Researchers have known that intestinal bacteria, known as gut microbiota, can affect the risk of complications from bone marrow transplantation such as graft versus host disease. A new MSK study found an association between the presence of a bacterial group and a lower risk that the patients leukemia or lymphoma will return after the transplant.

Developing a way to safely transplant bone marrow represents one of the great success stories in treating blood cancers such as leukemia and lymphoma. Still today, however, many patients who receive a transplant with donor cells suffer complications such as graft-versus-host disease (GVHD) when immune cells from the donor attack tissue in the recipient or relapse, when the underlying cancer comes back.

Researchers have known for decades that the makeup of bacteria in the gastrointestinal tract can impact how a patient fares following a transplant. In recent years, advances in computing power and genetic sequencing technologies have allowed Memorial Sloan Kettering researchers to get a clearer picture of how specific bacterial types in the gut affect risk of GVHD.

The bacteria could serve as a useful biomarker to guide patient treatment.

Jonathan Peled medical oncologist

Now a new study of MSK transplant patients has found a link between the presence of a particular bacterial group in the intestinal tract and a lower risk that the patients leukemia or lymphoma will return after stem cell transplantation. Patients harboring this bacterial group, made up primarily of the bacterium Eubacterium limosum, had their cancer come back at a significantly lower rate.

If this association is confirmed, the bacteria could serve as a useful biomarker to guide patient treatment, and possibly point to targets for therapies to improve survival after transplant, says MSK medical oncologist Jonathan Peled, who helped lead the study.

An essential next step will be to see whether this association holds true at other institutions that perform transplants.

The finding was reported in the Journal of Clinical Oncology by Dr. Peled along with Marcel van den Brink, Head of the Division of Hematologic Oncology, physician-scientist Robert Jenq (who recently joined the University of Texas MD Anderson Cancer Center), and additional researchers from MSK and other institutions.

The researchers studied all of the intestinal microbes (called the microbiota) contained in stool samples taken from 541 patients just before and just after an allogeneic transplant, which uses cells from a donor. They then examined the relationship between various bacterial types and whether the patients disease relapsed over the following two years.They found that only 19.8% of patients who had Eubacterium limosum in the gut relapsed during that period, while 33.8% of patients without Eubacterium limosum relapsed.

The researchers are unsure whether or how the bacteria may exert a protective effect or how directly that effect is imparted. Its possible that the bacteria somehow interact with the hosts immune system or the immune cells within the transplant graft or both.

Dr. van den Brink, who has helped lead much of the recent research at MSK on intestinal bacteria and transplant outcomes, says this finding provides more evidence that microbiota changes have a big impact. Patients undergoing bone marrow transplants have a major disruption in gut bacteria, both from receiving powerful antibiotics to relieve and prevent infection and from changes in diet and nutrition during the course of care.

Transplantation at MSK

The strengths of our transplant team include our specialization and knowledge, the advanced techniques we employ, and our unparalleled transplant nursing and supportive services.

You can put this finding into a row of recent studies showing that bacteria in the gut can have a big impact on tumor growth and immunity against tumors, he says. The next question is: Can we find this association in other patient groups at other transplant centers? We might find that the same kind of association exists but with a completely different bacteria that would not surprise me.

In addition to looking for the same bacteriarelapse link at other institutions, the researchers hope to shed light on the mechanism that might be responsible for this association. Does this bacterial group somehow influence the donor immune cells to hold cancer at bay so it does not rise again? Does it secrete a metabolite, such as a fatty acid, that is absorbed into the bloodstream that influences the immune response? If that metabolite is identified, could it be isolated and given to transplant patients?

Drs. Peled and van den Brink say these answers will be found mainly through conducting experiments in animals and performing a new, more sophisticated method of genetic analysis, called shotgun sequencing, on the bacteria itself. Shotgun sequencing decodes a genome by shredding it into smaller DNA fragments that are then assembled by computer programs that find which genes and synthetic pathways are present in the sample.

This newer approach lets us find out quickly how many genes a bacteria has for making a different metabolite, which gives clues to what they may be secreting, Dr. Peled says. This will provide insight into the biology of whats actually happening and how it may affect the immune response.

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Intestinal Bacteria May Affect Risk of Cancer Returning after Bone Marrow Transplantation - Memorial Sloan Kettering Cancer Center (blog)

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Mar 18th, 2017 | Filed under Diet Safely

News & Observer
BikeWalk NC director is driving change for cyclists and pedestrians
News & Observer
... easier for walking around, or riding a bike, he says. Everybody is talking about exercise and diet and getting healthy, and about having walkable and bikeable communities. All of these things come together when we can get out of our cars ...

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BikeWalk NC director is driving change for cyclists and pedestrians - News & Observer

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Mar 18th, 2017 | Filed under Diet Safely

Science Daily
New 'gene silencer' drug reduce cholesterol by over 50 percent
Science Daily
Researchers from Imperial College London and their colleagues, who conducted the trial, say the twice-a-year treatment could be safely given with or without statins, depending on individual patient needs. Eventually, inclisiran could help to reduce the ...

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New 'gene silencer' drug reduce cholesterol by over 50 percent - Science Daily

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Mar 18th, 2017 | Filed under Diet Safely

He has one job - to rid Downing Street of mice - but it appearsLarry the catis not up to the task, after he was caught on camera letting a rodent go.

Rather than hunting down the creatures Number 10 said in the past he prefersto take cat naps, but the latest incident confirms he may lack the killer instinct of many politicians who have lived there.

Photographer Steve Back, who captured the incident, said : Larry the chief mouser of Number 10came face to face with a tiny little mouse,which after some play time, got away safely.

The 10-year-old tabby has his own Twitter account with more than 107,000 followers, making him more popular than many MPs.

His Twitter account explained his latest failure to deliver by saying he was playing a tactical game, before claiming he was "on a diet".

It said: My friend @PoliticalPics thinks I look sleepy; Im actually just lulling the mice into a false sense of security...

Larry was recruited from Battersea dogs and cats home during the Cameron years to tackle the rampant mouse problem at the famous address

But after this latest incident,ssome have accused of failingto deliver the results expected of him.

He is one of several Whitehall pets, including Evia and Ossie of the Cabinet Office and dogs Rex and Oscar, who live upstairs at Number 10.

Larrys mousing skills are said to pale in comparison to those of his fellow moggies, Palmerston, who lives atthe Foreign Office, and Gladstone, who minds the Treasury.

David Cameron caused a minor outcry when he left office last year and failed to take Larry with him because he is an official civil servants cat rather than the Prime Ministers personal pet.

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Larry the Cat: Downing Street mouse-catcher caught failing to kill rodent - The Independent

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Mar 18th, 2017 | Filed under Diet Safely
XOMA Reports Fourth Quarter and Full Year 2016 Financial Results
P&T Community
A therapy that safely and effectively mitigates insulin-induced hypoglycemia has the potential to address a significant unmet therapeutic need for these rare medical conditions associated with hyperinsulinism. .... forms are more prevalent in patients ...

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XOMA Reports Fourth Quarter and Full Year 2016 Financial Results - P&T Community

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Mar 16th, 2017 | Filed under Diet Safely

B. Smith doesnt know the day, or the month or the year.

Early-onset Alzheimers disease has robbed the former restaurateur, model, author and TV host of such luxuries.

But her devastating 2013 diagnosis has created a national platform to address the disease that plagues an estimated 5.5 million Americans.

The brain is the most important thing in the body, the least understood and the most taken for granted, said Smiths husband, Dan Gasby. You can replace corneas, you can modify arteries, but the thing above your eyebrows you cant change.

Smith remained quiet throughout the interview Wednesday, while her husband spoke on her behalf about her condition.

Alzheimers is a type of dementia that causes problems with memory, thinking and behavior and once symptoms begin, there is no treatment.

Gasby also spoke at an event Wednesday night alongside his wife, highlighting Wake Forest Baptist Medical Centers new Alzheimers Center, funded by an $8.7 million grant from the National Institutes of Health.

The new center, one of 31 in the country, serves the Southeast, which has the highest rate of Alzheimers in the country.

(The center) places us on the cutting edge and allows us to help not only Winston-Salem but the entire region, said Suzanne Craft, director of the new center. For us, its a great opportunity to improve our knowledge about the disease and to translate that into better clinical care for patients and better education and assistance for families.

One of the focuses of the new center is research on early identification of Alzheimers, Craft said. By the time a person is diagnosed with Alzheimers disease, the brain has already been deteriorating for 15 to 20 years.

Smith, 67, began suffering from memory problems years before her diagnosis, her husband said. She once froze for several seconds while being interviewed on the Today Show, unprecedented for the experienced star, prompting a doctors visit.

Doctors gave Smith a prescription for anti-depressants; later tests revealed Smith had early onset Alzheimers.

She looked at me and she says were not going to hide, were not going to let someone else define us, Gasby said of the day Smith was diagnosed. Were going to tell our story.

Doctors explained that the progressive disease in the brain is like potholes in the road, so when neurons go astray when they try to send messages to other parts of the brain, causing behavioral fluctuations, Gasby said.

A few months after her diagnosis, Smith wandered away and was missing in New York City for a day before someone recognized her and she was safely returned home.

Its tough, Gasby said. Shes the greatest thing that ever happened to me and its tough watching this transition.

During her career, Smith wrote three cookbooks, founded three successful restaurants and launched a nationally syndicated TV show and a magazine. She had a successful home products line and is the only black woman to have her brand distributed exclusively at Bed Bath & Beyond. She became in 1976 the second black model to be on the cover of Mademoiselle magazine, after Joli Jones in 1969.

The Pennsylvania native was a candy-striper in high school and spent much of her life helping battered women and children, which makes it harder to see this happen to someone so inherently good, her husband said.

The odds are against her, as two-thirds of people with the disease are women. Blacks are also two times more likely to be diagnosed with Alzheimers.

The African-American community is the canary in the coal mine in America, so what happens to us usually ends up happening to the general population later, Gasby said. Of all diseases, this is the most dramatic because this is the one that separates you from your humanness.

In their years of advocating for awareness, Gasby said hes seen a problem, especially in the black community, with people not wanting to talk about issues like cognitive degeneration or dementia.

He likened it to the time he was diagnosed with prostate cancer and found out his best friend had the disease years before and never told him about it.

Thats the problem we dont talk about the things that really matter, Gasby said. Well talk about what the Kardashians are doing, whats the latest thing on some meaningless reality show, butthe things you dont talk about are the ones that can kill you.

The couple co-authored a book Before I Forget: Love, Hope, Help, and Acceptance in Our Fight Against Alzheimers and have partnered with the Brain Health Registry.

They said they hope to bring more awareness and incite more funding to a disease that will increasingly be a problem as people are living longer with modern technology and medicine.

Every 66 seconds, someone is diagnosed with Alzheimers, according to the Alzheimers Association. And each of those victims will need an average of three caregivers, so thats about 40,000 lives changing each week because of Alzheimers.

If that was Ebola, it would be a pandemic. If that was Zika, wed be nuking places with mosquito spray, so why arent we doing more for Alzheimers? he said. Thats what bothers me so much.

Gasby said what scares him most is that in 10 or 20 years, nothing about the disease and its treatment will have changed. While other diseases, like cancer, have made strides in recent years, research is essential to help deconstruct Alzheimers disease and find an effective treatment method.

He applauded the creation of the Wake Forest center in a state that ranks in the top 10 for Alzheimers disease. The center will also look at under-served communities with the disease and explore how diet and exercise affect cognition.

Smiths diagnosis has taught him a lot of life lessons, Gasby said, and he plans to spend the rest of his life fighting alongside his wife for awareness and a cure.

You learn time is precious and, that at the end of the day, you should do some good, Gasby said. We got dealt a tough hand but were going to play the hand for others, not just ourselves.

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B. Smith and husband, Dan Gasby, speak out against Alzheimer's disease - Greensboro News & Record

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Mar 16th, 2017 | Filed under Diet Safely

B. Smith doesnt know the day, or the month or the year.

Early-onset Alzheimers disease has robbed the former restaurateur, model, author and TV host of such luxuries.

But her devastating 2013 diagnosis has created a national platform to address the disease that plagues an estimated 5.5 million Americans.

The brain is the most important thing in the body, the least understood and the most taken for granted, said Smiths husband, Dan Gasby. You can replace corneas, you can modify arteries, but the thing above your eyebrows you cant change.

Smith remained quiet throughout the interview Wednesday, while her husband spoke on her behalf about her condition.

Alzheimers is a type of dementia that causes problems with memory, thinking and behavior and once symptoms begin, there is no treatment.

Gasby also spoke at an event Wednesday night alongside his wife, highlighting Wake Forest Baptist Medical Centers new Alzheimers Center, funded by an $8.7 million grant from the National Institutes of Health.

The new center, one of 31 in the country, serves the Southeast, which has the highest rate of Alzheimers in the country.

(The center) places us on the cutting edge and allows us to help not only Winston-Salem but the entire region, said Suzanne Craft, director of the new center. For us, its a great opportunity to improve our knowledge about the disease and to translate that into better clinical care for patients and better education and assistance for families.

One of the focuses of the new center is research on early identification of Alzheimers, Craft said. By the time a person is diagnosed with Alzheimers disease, the brain has already been deteriorating for 15 to 20 years.

Smith, 67, began suffering from memory problems years before her diagnosis, her husband said. She once froze for several seconds while being interviewed on the Today Show, unprecedented for the experienced star, prompting a doctors visit.

Doctors gave Smith a prescription for anti-depressants; later tests revealed Smith had early onset Alzheimers.

She looked at me and she says were not going to hide, were not going to let someone else define us, Gasby said of the day Smith was diagnosed. Were going to tell our story.

Doctors explained that the progressive disease in the brain is like potholes in the road, so when neurons go astray when they try to send messages to other parts of the brain, causing behavioral fluctuations, Gasby said.

A few months after her diagnosis, Smith wandered away and was missing in New York City for a day before someone recognized her and she was safely returned home.

Its tough, Gasby said. Shes the greatest thing that ever happened to me and its tough watching this transition.

During her career, Smith wrote three cookbooks, founded three successful restaurants and launched a nationally syndicated TV show and a magazine. She had a successful home products line and is the only black woman to have her brand distributed exclusively at Bed Bath & Beyond. She became in 1976 the second black model to be on the cover of Mademoiselle magazine, after Joli Jones in 1969.

The Pennsylvania native was a candy-striper in high school and spent much of her life helping battered women and children, which makes it harder to see this happen to someone so inherently good, her husband said.

The odds are against her, as two-thirds of people with the disease are women. Blacks are also two times more likely to be diagnosed with Alzheimers.

The African-American community is the canary in the coal mine in America, so what happens to us usually ends up happening to the general population later, Gasby said. Of all diseases, this is the most dramatic because this is the one that separates you from your humanness.

In their years of advocating for awareness, Gasby said hes seen a problem, especially in the black community, with people not wanting to talk about issues like cognitive degeneration or dementia.

He likened it to the time he was diagnosed with prostate cancer and found out his best friend had the disease years before and never told him about it.

Thats the problem we dont talk about the things that really matter, Gasby said. Well talk about what the Kardashians are doing, whats the latest thing on some meaningless reality show, butthe things you dont talk about are the ones that can kill you.

The couple co-authored a book Before I Forget: Love, Hope, Help, and Acceptance in Our Fight Against Alzheimers and have partnered with the Brain Health Registry.

They said they hope to bring more awareness and incite more funding to a disease that will increasingly be a problem as people are living longer with modern technology and medicine.

Every 66 seconds, someone is diagnosed with Alzheimers, according to the Alzheimers Association. And each of those victims will need an average of three caregivers, so thats about 40,000 lives changing each week because of Alzheimers.

If that was Ebola, it would be a pandemic. If that was Zika, wed be nuking places with mosquito spray, so why arent we doing more for Alzheimers? he said. Thats what bothers me so much.

Gasby said what scares him most is that in 10 or 20 years, nothing about the disease and its treatment will have changed. While other diseases, like cancer, have made strides in recent years, research is essential to help deconstruct Alzheimers disease and find an effective treatment method.

He applauded the creation of the Wake Forest center in a state that ranks in the top 10 for Alzheimers disease. The center will also look at under-served communities with the disease and explore how diet and exercise affect cognition.

Smiths diagnosis has taught him a lot of life lessons, Gasby said, and he plans to spend the rest of his life fighting alongside his wife for awareness and a cure.

You learn time is precious and, that at the end of the day, you should do some good, Gasby said. We got dealt a tough hand but were going to play the hand for others, not just ourselves.

See more here:
B. Smith's husband, Dan Gasby, speaks about living with wife's Alzheimer's - Winston-Salem Journal

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Mar 16th, 2017 | Filed under Diet Safely

B. Smith doesnt know the day, or the month or the year.

Early-onset Alzheimers disease has robbed the former restaurateur, model, author and TV host of such luxuries.

But her devastating 2013 diagnosis has created a national platform to address the disease that plagues an estimated 5.5 million Americans.

The brain is the most important thing in the body, the least understood and the most taken for granted, said Smiths husband, Dan Gasby. You can replace corneas, you can modify arteries, but the thing above your eyebrows you cant change.

Smith remained quiet throughout the interview Wednesday, while her husband spoke on her behalf about her condition.

Alzheimers is a type of dementia that causes problems with memory, thinking and behavior and once symptoms begin, there is no treatment.

Gasby also spoke at an event Wednesday night alongside his wife, highlighting Wake Forest Baptist Medical Centers new Alzheimers Center, funded by an $8.7 million grant from the National Institutes of Health.

The new center, one of 31 in the country, serves the Southeast, which has the highest rate of Alzheimers in the country.

(The center) places us on the cutting edge and allows us to help not only Winston-Salem but the entire region, said Suzanne Craft, director of the new center. For us, its a great opportunity to improve our knowledge about the disease and to translate that into better clinical care for patients and better education and assistance for families.

One of the focuses of the new center is research on early identification of Alzheimers, Craft said. By the time a person is diagnosed with Alzheimers disease, the brain has already been deteriorating for 15 to 20 years.

Smith, 67, began suffering from memory problems years before her diagnosis, her husband said. She once froze for several seconds while being interviewed on the Today Show, unprecedented for the experienced star, prompting a doctors visit.

Doctors gave Smith a prescription for anti-depressants; later tests revealed Smith had early onset Alzheimers.

She looked at me and she says were not going to hide, were not going to let someone else define us, Gasby said of the day Smith was diagnosed. Were going to tell our story.

Doctors explained that the progressive disease in the brain is like potholes in the road, so when neurons go astray when they try to send messages to other parts of the brain, causing behavioral fluctuations, Gasby said.

A few months after her diagnosis, Smith wandered away and was missing in New York City for a day before someone recognized her and she was safely returned home.

Its tough, Gasby said. Shes the greatest thing that ever happened to me and its tough watching this transition.

During her career, Smith wrote three cookbooks, founded three successful restaurants and launched a nationally syndicated TV show and a magazine. She had a successful home products line and is the only black woman to have her brand distributed exclusively at Bed Bath & Beyond. She became in 1976 the second black model to be on the cover of Mademoiselle magazine, after Joli Jones in 1969.

The Pennsylvania native was a candy-striper in high school and spent much of her life helping battered women and children, which makes it harder to see this happen to someone so inherently good, her husband said.

The odds are against her, as two-thirds of people with the disease are women. Blacks are also two times more likely to be diagnosed with Alzheimers.

The African-American community is the canary in the coal mine in America, so what happens to us usually ends up happening to the general population later, Gasby said. Of all diseases, this is the most dramatic because this is the one that separates you from your humanness.

In their years of advocating for awareness, Gasby said hes seen a problem, especially in the black community, with people not wanting to talk about issues like cognitive degeneration or dementia.

He likened it to the time he was diagnosed with prostate cancer and found out his best friend had the disease years before and never told him about it.

Thats the problem we dont talk about the things that really matter, Gasby said. Well talk about what the Kardashians are doing, whats the latest thing on some meaningless reality show, butthe things you dont talk about are the ones that can kill you.

The couple co-authored a book Before I Forget: Love, Hope, Help, and Acceptance in Our Fight Against Alzheimers and have partnered with the Brain Health Registry.

They said they hope to bring more awareness and incite more funding to a disease that will increasingly be a problem as people are living longer with modern technology and medicine.

Every 66 seconds, someone is diagnosed with Alzheimers, according to the Alzheimers Association. And each of those victims will need an average of three caregivers, so thats about 40,000 lives changing each week because of Alzheimers.

If that was Ebola, it would be a pandemic. If that was Zika, wed be nuking places with mosquito spray, so why arent we doing more for Alzheimers? he said. Thats what bothers me so much.

Gasby said what scares him most is that in 10 or 20 years, nothing about the disease and its treatment will have changed. While other diseases, like cancer, have made strides in recent years, research is essential to help deconstruct Alzheimers disease and find an effective treatment method.

He applauded the creation of the Wake Forest center in a state that ranks in the top 10 for Alzheimers disease. The center will also look at under-served communities with the disease and explore how diet and exercise affect cognition.

Smiths diagnosis has taught him a lot of life lessons, Gasby said, and he plans to spend the rest of his life fighting alongside his wife for awareness and a cure.

You learn time is precious and, that at the end of the day, you should do some good, Gasby said. We got dealt a tough hand but were going to play the hand for others, not just ourselves.

Read the original here:
B. Smith and husband, Dan Gasby, speak out against Alzheimer's disease - Winston-Salem Journal

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Mar 16th, 2017 | Filed under Diet Safely

Hemp seed flour is a newcomer to the world of cooking. There are many reasons why this flour is making a strong presence in the dietary world, and here are just a few:

1. Hemp seed flour contains no gluten. While gluten is a great contributor to giving rise and a fluffy texture to many baked goods, it can also cause a variety of gastrointestinal symptoms. These ills have recently been found to be related to medical conditions such as celiac disease, wheat allergy, non-celiac gluten sensitivity and other autoimmune conditions.

2. Hemp flour does not use bleaching agents to speed up the flours aging process. One bleaching agent, chloride oxide, produces alloxan. Alloxan is a poison and causes diabetes in laboratory animals. Chlorine oxide also destroys the vital wheat germ oil, and it will shorten the flours shelf life and nurture insects. (Ever wonder why bugs appear in white flour?)

3. Hemp seed flour contains all 8 essential amino acids. While hemp seed is not the only plant seed that can state this claim, it is the only one that has the correct ratio in the form of globulin edestin at 65% of the protein content. What this means is that hemp seed provides a perfectly suited ratio to aid in meeting the bodys cellular need, such as DNA repair.

4. Refining methods are limited in hemp seed flour to protect nutrients. It is a known fact that refining destroys essential nutrients from foods. When white bleached flour is processed, 98% of magnesium is destroyed, 80% of iron is eliminated and all of the vitamin E is erased. Hulled hemp seed retains all fiber, magnesium, phytosterols, ascorbic acid, beta-carotene, calcium, iron, potassium, phosphorus, riboflavin, niacin and thiamin.

5. Hemp seed flour contains no unsaturated fatty acids. Plants have created the perfect container to safely store the EFAs (essential fatty acids) and protect them from light and oxygen damage. It is the seed. Life cannot flow without the light and oxygen sensitive EFAs. The antioxidants and free radical scavengers that control the oxidation rate are protected through natures unique balance of hemp seed.

In a world where sickness and disease appear to be running rampant, there are steps that can be taken through diet by looking to organic sources. Hemp seed flour is a perfect way to begin your regiment of living healthier and feeling better.

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Why Hemp Flour is Better Than White Bleached Flour - The Marijuana Times

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Mar 16th, 2017 | Filed under Diet Safely

MADISON, NJ -- Right on cue with the areas fitness explosion TheMAX Challenge, one of the nations fastest growing fitness concepts, is about to call downtown Madison home.

Located in the previously departed"Season's Gift Shop" space at 35 Main StreetTheMAX Challenge ofMadison will open it's doorsin the Madison communitySunday, March 26 at 8a.m.with a grand opening celebration to kick off their first local session on Monday March 27.

Intimidated? Don't be. The MAX Challenge is a comprehensive 10-week body and mind renewal program, combininga structured workout regimen with an easy-to-follow nutritional guide to help achieve and sustain optimal health and fitness.

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"The program promotes a slow and systematic approach toward attaining physical success by educating members on the impact a balanced nutritional diet and positive mental attitude have on maintaining a healthy lifestyle," said co-ownersToby Bavli and Greg Kleimanwho also own a MAX Challenge studio in Montclair, NJ.

All participants are provided with a certified MAX Instructor who is present at all times to ensure that members execute each exercise safely and efficiently. Additionally, instructors alternate exercise routines daily to avoid monotony and to ensure that members remain fully engaged, and most importantly, enjoy the time they spend reaching the peak of their physical abilities.

Our goal is to make our members not only healthier people, but happier people, stated Bavli andKleiman. We are elated to open our newest location, and look forward to changing lives with our unique body renewal system.

ABOUT THE PROGRAM The 10-week body renewal system was designed to help members make fast and lasting changes to their health, appearance, and fitness levels. "We help members achieve great results by receiving a combination of nutritional counseling, fitness classes, and motivation provided by trained MAX Challenge instructors," said Kleiman.

"We chose Madison to open our second location because,we love the family feel here, it isa real close knit community, the Main streetwas a huge draw for us. The people here we have met so far are amazing and we can not wait to meet more. We may bea franchise conceptbutwe are hands on ownersand we loveall the perks of a walking town like Madison.We feel the location and community is perfect for our model because we are a community building facility, we know if you want to succeed it takes a village, and we love to be involved in charities, festivals, in town events, and giving back to make a difference to those in need through healthy living."

A typical 10-week session for amember includes, 45 minute classes Monday through Friday, we have an online "secret/ closed" group with tons of nutrition information, weekend workshops for ongoing recipes, Pot Lucks, cooking demos with the local Whole foods. We take measurements of our members during their 10 weeks with us to keep track of their progress and a before/ after picture which is only for their view. We have a ton of staff members who want the best for everyone and will make sure the classes are the best and most fun around."

There is a daily rotation of fitness classes consisting ofCardio on Monday and Wednesdays all day, then Tuesday focuses on upper body sculpting and toning with weight training,Thursdayislower body strength training day, and Friday ends the week with a cardio kickboxing session."We do this to hit all muscles through out the week for the ultimate weight loss by the end of your 10 weeks," they said.

Pricing for the 10-weeks is a flat rate of$349which includes 50 classes during your 10 weeks and weekly nutritional counseling as well as access to meal prep deliveryservices, attendance tracking, and constant support."We have classes that run from5a.m. to6a.m. for the commuting crew or the people who need to get back before another family member commutes and then throughout the day until7:00p.m. We always get a group of parents around the8:45/9:45a.m.class as well. Each group throughout the day organically has a little different personality flavor,and we love it all,"said Bavli.

"It is funny, clients come in at first and are nervous, they could be out of shape and over-weight, they could want a body/health shiftdue to new lifestyle changes or could just want to try something new with some friends, but they should not be nervous, this is a personal journey for each person and at the end of the day they are just really excited about their new outlook."

There are over 70 MAX Challenge locations throughout New York, New Jersey, California, and Florida as well as many additional locations in the opening stage.To learn more about THE MAX Challenge, please visithttp://www.themaxchallenge.com

Originally posted here:
Max Challenge Announces Grand Opening In Madison March 26; Join The Fun - TAPinto.net

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Mar 16th, 2017 | Filed under Diet Safely
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