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When June comes around faster than a bullet train and we still haven't shed the extra padding from a winter of working from home, what is there to do but look for healthy ways to detox?One often-cited study shows that the best way to jumpstart weight loss and improve gut health (to lower inflammation)quickly is a short but deliberate juice fast, even if you only swap out some of your meals for juicing.

By increasing the number of fruits and vegetables you intake, by juicing, you can positively impact your gut's balance of micro-organisms, which make up your microbiome, to switch it over toward healthy bacteriawhich feed on vegetables, fruit, and the fiber they containfrom those that feed on saturated fat, meat, dairy, and toxins. Thatmeans you will not only lose weight but create a cascade of health benefits throughout the body that include opening up your blood vessels, delivering more oxygen to the muscles (with nitric oxide from the fruit and vegetable juice), and allow yourself to feel more energetic, recover from workouts faster and feel all-around more like Superman or Superwoman, all from just adding plant-based foods to your diet, the more the better.

According to the study, justthree days of juicing is enough to switch over the gut microbiome from inflammatory bacteria to good bacteria, meaning you train your body to shed pounds and hit reset, fast.

There's no better way to lose weight and do a healthy cleanse, thestudy tells us than to start juicing, at least one meal a day. Juicing, especially with a variety of vegetable juices from beets, dark leafy greens, and other intensely colored vegetables, adds important plant antioxidants, present in the pigments of the juice, called polyphenols that not only help us shed fat faster but detox all those extra empty calories and unhealthy gut bacteria from a long weekend of over-indulging (with booze, meat, sweets, and whatever else we allowed ourselves in the name of enjoying thelong-awaitedchance to socialize withfriends). Juicing works by adding fiber and nutrients to your body and allowing your gut to empty itself of bad bacteria that metabolize meat and dairy to the so-called healthy gut bacteria that fights inflammation, and literally start fresh.

"Vegetable and fruit juices provide polyphenols... fiber, and nitrates (especially in beet juice), which may induce a prebiotic-like effect," the study authors state. They set out to find out if three days of juicing would have significant health benefits and found that on day four, all serious health markers were improved, including weight loss.

The study put 20 healthy adults on ajuice diet for threedays and then had them eat normally afterward for 14 days, and the weight loss from the juicing lasted until the end of the experiment, so even after the subjects went back to their customary diet, the juice fasting weight stayed off, indicating that this type of new healthy gut microbiome was doing its job.

"On day 4 we observed a significant decrease in weight and body mass index," the authors reported, "which was maintained until day 17. On day 4 the proportion of the phylum Firmicutes and Proteobacteria [bad bacteria] in stool was significantly decreased and Bacteroidetes and Cyanobacteria [good bacteria] was increased compared to baseline and was partially reversed on day 17."

Also on day four, they reported that "plasma and urine nitric oxide was increased by 89 percent and 360 percent, respectively," while the number of unhealthy lipids in the body had fallen by more than 20 percent, which meant that heart health was also improved. "General well-being score was increased at the end of the study," the authors concluded. "In summary, a 3-day juice-based diet altered the intestinal microbiota associated with weight loss," which stayed off for 17 days of the study, and an increase inNitric Oxide, plus adecrease in lipid oxidation.

This was so significant that even a partial juice fast is likely to benefit you. Here is how to make a healthy green juice based on this study, with green vegetables, and a small amount ofmint, cucumber, and lemon juice to sweeten the drink enough to make it palatable.

For five detox juice recipes to cleanse your body and lose weight, click here.

Serves 1

Beet juice, specifically, carries more health benefits than other vegetables or plants, because of the fact that it contains a plant pigment that makes it an intense color or red called betalains. These phytochemicals are believed to give beetsthe ability to keep blood pressure low by helping blood vessels stay supple, open, and allow blood to freely flow through them. But they are also indicated in studies as helping the body infighting cancer, a fact that experts agree makes beet juice a uniquely powerful ingredient to add to your daily routine.

Beets get their rich color from betalains, which are water-soluble antioxidants, according to a studypublished in 2016. "Betalains have chemo-preventive capabilities against some cancer cell lines in the body, explains Shannon Henry, RD, a registered dietitian withEZCare Clinic,an online healthcare service. Betalains are thought to help your immune system search for free radicalsand neutralizeunstable cells in the body.

Inyet another recent study,researchers gave obese female patients a mix of dried fruit and a high-fiber drink of vegetable concentrate and found that the effect of the phytochemicals, or plant-based nutrients, from the fruits and vegetableshelped to reduce blood sugar and lower insulin resistance, so fiber from dried fruit can be beneficial as a snack while you are juicing since the fiber can also act as a prebiotic toimprove guthealth.

Serves 1

The Top 20 Veggies with the Most Protein

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Diet. One of those words you hear on the 1st of January or, more commonly, on Mondays when someone attempts to turn their eating habits upside down in order to lose weight, gain muscle, or feel better overall. If you are thinking of losing weight, perhaps you should try the volumetrics diet.

The volumetrics diet was created by Barbara Rolls, a PhD. professor and chair of Nutritional Sciences at Pennsylvania State University, in the United States, where she heads the Laboratory for the Study of Human Ingestive Behavior.

In April 2012 she published a book called The Ultimate Volumetrics Diet: Smart, Simple, Science-Based Strategies for Losing Weight and Keeping It Off. The book is co-author by Mindy Hermann, a writer who specialises in collaborative projects on cooking, food, and nutrition with researchers, health professionals, and chefs.

Although a decade old, the diet has only recently become more known to the general public. It ranked 5th Best Diets Overall by U.S. News & World Reports annual rankings, and 3rd Best Fast Weight-Loss Diets.

So, the question on everyones mind is: does it work? We talked with Justin Romaire, nutrition coach, founder and CEO of Consistency Breeds Growth to get a professional opinion about it. Its a great way to get people to lose weight, he said.

Disclaimer: all content within this article is provided for general information only and should not be treated as a substitute for the medical advice of your own doctor or any other health care professional.

The golden rule of the volumetrics diet is that you should eat larger portions of low-calorie foods and restrain from high-calorie foods. By doing this, Barbara Rolls explains, your body will feel fuller while ingesting fewer calories, thus helping with weight loss.

That means you should not feel hungry at all during the day if you adopt the volumetrics diet. At the end of the day, you will be consuming somewhere between 1,600 and 2,000 calories.

This diet does not focus solely on your nutrition, but also on your physical activity, as it encourages people to exercise 30 to 60 minutes every day.

Watch the extensive virtual conversation Barbara Rolls had at Penn State University earlier this year.

Every food is separated into four different categories:

Category one should make the bulk of your daily meals with reasonable portions of category two foods. Foods that fall under category three should be consumed in moderation, while category four foods should be eaten only occasionally.

When it comes to exercise, the volumetrics diet encourages you to add 150 steps a day to your routine most phones have a pedometer, or you can download an app for that. The first goal is to increase 1,000 steps daily by the end of the first week. The ultimate goal is to log in at least 10,000 steps every day.

Read More: Running for Beginners: A Guide to Building Confidence & Keeping Routine

The diet is flexible enough for vegetarians, vegans, and those who need to restrict salt and fat.

My personal opinion, Justin Romaire tells us, is for weight loss, [the volumetrics diet] is a better approach than a restricted diet. When you get into restricting foods, that is not sustainable for people.

Barbara Rolls book can help you learn the calorie density of the foods you want to eat and they also provide a food density list for hundreds of foods that will help you prepare your next meal.

A good tip to keep in mind when going grocery shopping is to look for foods that are high in water content, as water has no calories. Think tomatoes, cucumber, grapefruit, zucchini, watermelon, broccoli, cauliflower and apples.

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Mike Posner is on top of the world literally.

On June 1, the EDM star summited Mount Everest, the highest mountain in the world, after a 50-day trek. Two days later, on June 3, he shared video of his stunning perspective.

"This morning at 4:35 am, Dawa Chirring Sherpa, Jon Kedrowski, Dawa Dorje Sherpa and Mike Posner summited Mt Everest. That's what I call a sunrise," he said on Twitter this week. "We are now back at camp 2 but not out of the woods until we descend to base camp tomorrow am. Please keep us in your prayers."

Seemingly in a safer spot, on June 3, Mike posted a video with his team from 29,000 feet above sea level.

"Now that's what I call a sunrise. This was hard. I'm exhausted beyond any point of exhaustion I could've conceived of before," he wrote on Instagram alongside the amazing view. "Taking sometime for me but will share some more memories with you once I've had time to process it all."

Mike made the harrowing climb to raise money for the Detroit Justice Center, as he often spoke of the cause during his nearly two-months of climbing. TMZ reported that Mike has thus far raised $229,000 with the climb.

Dr. Jon Kedrowski, one the men on the climb with Mike, posted a video of his own on June 3.He also lauded the music creator for his commitment.

"The sunrise from the top of the world was special, it made me realize once again that the past 20 months of this journey since I first met Mike and was given the privilege to coach him, work with him, and prepare him to help make his dream a reality was a true blessing and adventure I'll always be grateful for," Dr. Kedrowski wrote. "He basically worked on his craft for 20 months all for a shot at a mere 20 minutes on the summit. What a real sacrifice! But over the past nearly two years I also got to see why and how he is such an incredibly talented world class musician."

"He applied that world class work ethic and never wavered in his preparation and desire to dream and also dedicate himself to being the best mountaineer he could be," the caption continued. "He fully immerses himself in his dreams and goals and never stops working at it. This is a valuable lesson we can all take with us."

While on the mountain, the group apparently waited for two tropical cyclones to pass.

"What I learned on this expedition and during my time working with Mike was that his famous slogan#keepgoingis so very true," Dr. Jon said. "Even when we could have quit and gone home like Many others, we went up the mountain again, this time in deeper snow than before. But the most important lesson is that we listened to the mountain, and when the storms cleared mighty Sagarmatha let us in for awhile (8 days on the mountain during the summit push)."

Back in 2019, Mike famously walked from New Jersey to California after being inspired by the deathsof his father and fellow EDM superstarAvicii. He said that he began thinking of conquering Mount Everest while crossing the Rocky Mountains in Colorado and Utah.

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Raven-Symon skewered over 28 pound weight loss and 48-hour fast - Wonderwall

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

BEFORE kickstarting a new diet and exercise plan, the first thing we always have to swear off is McDonald's - because we've proved time and time again that we have no self-control when it comes to a McChicken sandwich.

But while we always assumed that indulging in fast food is the worst thing you can do on a diet, this personal trainer claims he's tucking into a McDonald's everyday for two weeks - and STILL managing to lose weight.


Documenting his weight loss plan on TikTok, fitness instructor Oisin Mulligan explained how he still shed pounds while eating the food he enjoys.

In the first video in the series, the trainer - who specialises in weight loss - said: "I'm doing this to remove fear surrounding food.

"No food will inherently make you gain weight - even if that food is a Big Mac from McDonald's."

At the start of the experiment, Oisin weighed 82.1kg [12 stone 9lbs] - and 11 days in, he's lost 1.7kg.


Explaining how he planned to lose weight, Oisin added: "I'm doing it by staying in a calorie deficit.

"Essentially, our body burns so many calories per day or utilises so much energy every day and if you just eat a little bit less than that, no matter what you eat, within that you will lose weight."

Everyday Oisin has filmed himself ordering something different from the McDonald's menu - but has made sure to squeeze in 10,000 steps too.

He claimed: "If this doesn't show that calories are the deciding factor in weight loss then nothing will.

No food will inherently make you gain weight - even if that food is a Big Mac from McDonald's

"All diets work by creating a calorie deficit - but most do it by restricting full food groups, such as carbs. And I'll say it again, restriction leads to failure!"

Although he doesn't advise his clients eat junk food everyday, Oisin wanted to challenge the notion that McDonald's is "bad".

He continued: "People feel afraid of certain foods or feel like they can't consume the foods they enjoy and lose weight at the same time.

"If someone calls your food bad or says McDonald's is inherently bad or your chocolate bar is bad, when you consume that food, it makes you feel bad."


Needless to say, Oisin's videos have been a hit with his 12,900 followers.

"Love this message," one replied. "Got to remove food fear! Great videos."

Another added: "Loving this journey!"

Meanwhile, a third wrote: "I really need your videos at the moment.

"I've put on weight from treatment for a tumour and I'm punishing myself for eating."

When quizzed about his vitamin intake, Oisin replied: "There are plenty of other foods involved - I wouldn't recommend any one else eat it everyday."

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For more health stories, this expert revealed why you SHOULDNT sleep naked in a heatwave & it could actually be making you hotter.

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Plus the TikTok sandpaper leg shaving trend was slammed as experts say DONT try it.

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Im eating McDonalds every day for two WEEKS & still losing weight people shouldnt be afraid of it... - The Sun

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Winter can be one of the most difficult seasons in which to try and lose weight but with a little bit of determination can be the most rewarding time of the year to get into shape.

For Hollywood stars there is always the pressure to look your best and weight loss is no exception. In recent times, celebrities have been quite vocal about being body-shamed by fans and peers but at the same time many celebs continue to work hard to stay fit and healthy.

Actress Raven-Symon from Thats So Raven fame is the latest Hollywood celeb to share her weight loss journey with the world. She shared her incredible weight loss news after losing over 17kg. She posted her success in a video posted on Instagram.

While on a road trip with her wife Miranda Pearman-Maday, she told fans: "Pounds (kgs) down, pounds down. Check out the chin. The 35-year-old star said: Right now Im doing a 48-hour fast, so were on that journey right now."

A 48-hour fast is an extended form of intermittent fasting. It involves not consuming any calories for a full 2 days.

While the fast involves eliminating foods that contain calories, it is still important to drink plenty of non-caloric fluids, such as water, herbal tea, and black coffee throughout the fasting period to keep your body hydrated.

Some people may use a 48-hour fast to reduce their calorie intake and help them lose weight. Others may use the fast to support digestive health.

A review article in behavioural sciences reported that intermittent fasting produces similar short-term weight loss results as traditional continuous calorie restriction in people with overweight and obesity. Therefore, cutting excess calories from the diet may be just as effective as fasting for weight loss.

Fasting may also affect people with underlying conditions differently. People with diabetes who take insulin or are on blood sugar-lowering medications will need to check with their doctor before engaging in any type of fasting, as fasting can drastically change how some medicines and insulin work.

Another famous face, Jonah Hill has been open and honest about his weight gains and losses since landing his first leading role in 2007's Superbad.

Hill lost weight by correcting his unhealthy diet, he told ABC News at the time: "I wish there was some crazy thing that I did, like a pill or a genie or something, but I went to see a nutritionist, and he told me what to eat to change my habits and stuff."

In a sit-down interview with Ellen DeGeneres, the 34-year-old actor said growing up in the spotlight left him vulnerable to criticisms about his body.

I think everybody has a version of themselves I call it a snapshot at some point in life trying to hide from the world. Even if you get success or grow up or become good-looking or whatever ... you kind of carry some part of that with you," he told DeGeneres.

For me, its definitely being like this 14-year-old kid, being overweight, wanting to fit in with these skaters and hip-hop kids, and just feeling lonely and maybe not understanding my own worth.

Locally, rapper and TV personality Proverb shared an impressive weight loss journey once. The Idols presenter, whose real name is Tebogo Thekisho, in the past told Soweto Live that at a weight of 100kg, which was his heaviest, he couldnt play with his kids as much as he wanted to.

"I do not want to get all these weight-related illnesses like high blood pressure and want to live long enough to raise my kids," he said.

"I got to a point where I was uncomfortable in my own skin, I was lazy all the time and too tired to get involved in anything. I saw myself as a mess, especially on my TV shows. I decided in January to take action and challenge myself to lose weight to avoid health scares." he said.

Last year, the Mo and Mome star, Mome Mhlangu revealed she achieved her weight loss by eating clean and exercising. When she started off her weight loss journey, she was a busy mom to three kids and weighed 110 kg. At that time, she wrote: From 110kg at 27 to 64kg at 36 with three kids it's your journey and your patience is required to reach your goal.

She has now established her own health and fitness products with Moringa being the main ingredient. The powder can be added to any meal and there is also a tonic alongside others.

She now maintains a healthy lifestyle and is dedicated to cooking healthy meals for her husband and children.

Most celebrities lose weight because they want to fit in. For some it's part of their job and it's how they make money. Whatever reason you want to lose weight, get some motivation from these stars and kick-start your health journey

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Losing weight is a culmination of several activities, such as exercise, a low-calorie diet, and consuming foods and drinks that burn calories. You gain weight when you eat more calories than your body actually needs. The excess calories are converted into fat cells, making you heavier in the long run. To lose weight, there must be a balance between calorie intake and calorie expenditure. You can also lose weight by eating low-calorie foods and drinks or foods and drinks that burn your excess fats and flush them out of your body.

Weight Loss Drink Recipes

Here are some drink recipes that will help you burn calories and detoxify your body:

Slimming and detox waterox

What you need

How to prepare

How to use

Fat Burning Detox Water

What you need

How to prepare

How to use

Belly fat burning detox drink

What you need

How to prepare

How to use

Lemon Berry Fat Flush Drink

What you need

How to prepare

How to use

Fat Burning Detox Tea

What you need

How to prepare

How to use

Orange-Lemon Slimming Drink

What you need

How to prepare

How to use

Mandarin Grapefruit Weight Loss Drink

What you need

How to prepare

How to use

How it works

Benefits of slimming drinks

One of the best ways to lose weight is to drink slimming drinks. Here are some of the benefits of weight loss drinks:

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Lose weight fast with these slimming drinks - Filmy One

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Surgery is usually a highly invasive procedure that takes a toll on your body as it works overtime to promote healing. Depending on the type of surgery you have, your recovery may be a short or lengthy process.

In some cases, you may experience some weight gain after surgery as a result of fluid retention, a side effect of medication, or being sedentary for a long time. However, this depends on the type of surgery, the expected recovery time, and your medical history (1, 2).

Weight gain during the initial recovery period is usually not a result of gaining fat mass but rather an accumulation of fluid as part of the healing process. In most cases, postsurgical weight gain is temporary and subsides as your body recovers.

However, prolonged recovery time, physical inactivity, stress, and changes in your eating behavior can lead to weight gain over time. Therefore, its important to try to resume your usual healthy lifestyle as soon as it is safe to do so.

While usually temporary, postsurgery weight gain can occur in people who have excess fluid buildup and swelling. Physical inactivity, stress, and changes in eating habits can also lead to weight gain, depending on the length of your recovery time.

There are many potential causes of weight gain after surgery.

The most common cause of weight gain after surgery is fluid retention, also known as postoperative edema.

Edema occurs when extra fluid builds up in your body to respond to inflammation and promote healing. It may also be caused by intravenous (IV) fluids given during surgery. Edema can be localized (in one spot) or generalized (throughout your body) (3, 4).

Common symptoms of edema include puffiness, swelling, decreased mobility at the joints (e.g., fingers, ankles, wrists), decreased urine output, and rapid weight gain (3, 4).

Though it usually subsides on its own, in some cases, your surgeon may recommend a prescription diuretic to reduce swelling or adjust other medications youre taking that may promote edema, such as corticosteroids or calcium-channel blockers (3).

They may also suggest wearing compression clothing, engaging in gentle movement, reducing salt intake, and elevating the affected area. If you have concerns about swelling and edema, its best to talk with your surgeon or another medical professional (3).

Depending on the type of surgery you have, you may need to limit your physical activity for days to weeks afterward.

Though a few days of rest wont cause substantial weight gain, prolonged sitting paired with physical inactivity for extended periods of time can lead to a decrease in muscle mass and daily calorie expenditure. As a result, your fat mass may increase (5).

Fortunately, rehabilitation is a large component of postsurgical care. It includes seeing specialists such as physiotherapists and occupational therapists, who can help you return to your normal activities and reduce muscle wasting (6, 7).

If you had a minor surgery with a short recovery time, allow yourself to rest before slowly reintroducing your usual physical activities. After a major surgery, you may need to rest for an extended period before resuming exercise.

Once you can safely resume exercise, slowly reintroduce gentle movement, such as walking or yoga, to see how you feel and tolerate it. You may need to gradually reintroduce straining activities, such as lifting weights, or avoid them until youre fully recovered.

Though it may be tempting to return to your normal fitness routine once you start feeling better, be sure to speak with your doctor and receive medical clearance first.

Recovering from surgery can be painful, stressful, and emotionally draining. This may have you reaching for your favorite comfort food to help you cope.

However, if you continue to rely on comfort food rather than return to a more balanced diet after youve recovered, you may experience weight gain over time.

During your initial recovery, its important to focus on consuming enough calories and protein to promote recovery, even if you can tolerate only certain foods, such as ice cream, pudding, Jell-O, or scrambled eggs (8, 9).

Depending on your surgery and preoperative nutrition status, you may work closely with a registered dietitian as part of your postoperative care.

They may recommend a therapeutic diet, such as liquids only, or additional supplements, such as protein or energy shakes, to support your recovery (8).

However, as you regain your appetite and ability to eat, focus on reintroducing foods high in protein to support healing and prevent muscle loss. Further, eating high fiber foods will help promote bowel regularity and reduce constipation, which is common after surgery (8).

If youre hungry between meals, try eating small snacks that contain protein and fiber such as peanut butter and apple slices which will keep you satisfied and full.

Additionally, try to stick with low calorie drinks like water, coffee, and tea instead of sugary beverages or alcohol.

Its OK to enjoy comfort foods as part of your recovery. Allow yourself the flexibility to eat foods that feel good for you in the moment. However, if you begin to use food or alcohol as a regular coping mechanism, speak with a dietitian or medical professional.

Edema, or fluid accumulation, can lead to weight gain that will go down as you recover. Inactivity and comfort eating may also contribute to body fat gain. To minimize weight gain, try to resume regular physical activity and healthy eating once youve recovered.

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Weight Gain After Surgery: Causes and How to Prevent It - Healthline

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

An Irish personal trainer is eating McDonalds every day for two weeks to prove that, when it comes to losing weight, its not what you eat but how much of it.

Westmeath fitness instructor Oisin Mulligan has racked up hundreds of thousands of views on his Instagram and TikTok pages since beginning the challenge eight days ago.

On Lunchtime Live this afternoon, he said the challenge was about showing people they dont need to cut out the foods they enjoy if they want to lose weight.

Personal trainer aiming to prove he can eat McDonalds everyday and lose weight

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He said he is not encouraging anyone to eat fast food every day but is trying to show that, even if you did, it is not necessarily going to affect your weight in a negative way.

I am eating McDonalds well one item from the menu every single day for two weeks and losing weight at the same time, he said.

Im doing it by staying in a calorie deficit. Essentially, our body burns so many calories per day or utilises so much energy every day and if you just eat a little bit less than that, no matter what you eat, within that you will lose weight.

Thats what I am trying to show everyone that you dont have to cut out the foods you enjoy.

As a personal trainer, Mr Mulligan uses exercises five or six times a week; however, he is cutting that out for the duration of the challenge to show that, provided he maintains a calorie deficit, he wont gain weight.

I think a lot of people have taken a lot from it, he said. People feel afraid of certain foods or feel like they cant consume the foods they enjoy and lose weight at the same time.

If someone calls your food bad or says McDonalds is inherently bad or your chocolate bar is bad, when you consume that food, it makes you feel bad.

So, Im trying to remove that and a lot of people have been interacting with me saying Jesus, you opened my eyes to that food isnt going to inherently make me put on weight.

It is the amount of food or how many calories I intake not necessarily the type of food.

He said he still aims to do 10,000 steps per day and, outside of his daily trip to McDonalds, he is eating healthy foods.

I actually cut back my training completely to show people that you dont actually have to do extreme exercise to lose weight either, he said. Your body will burn calories lying in your bed.

If you were to go into a coma - it is called your basic metabolic rate - essentially you would burn calories in that coma and the hospital would have to feed you so many calories to keep you going.

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

PLAINSBORO, N.J., June 4, 2021 /PRNewswire/ --Novo Nordisk today announced that the US Food and Drug Administration (FDA) has approved the new drug application (NDA) for Wegovy (semaglutide) injection 2.4 mg, the first-and-only prescription weight-loss medication with once-weekly dosing. Wegovy is used with a reduced calorie meal plan and increased physical activity foradults with obesity (BMI 30) or overweight (excess weight) (BMI 27) who also have weight related medical problems to help them lose weight and keep the weight off.1

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Approximately 42% of adults in the US live with obesity, a chronic disease which is recognized by the Centers for Disease Control and Prevention (CDC) as an epidemic.2,3 Obesity is a gateway disease associated with at least 60 other serious health conditions and decreased life expectancy.4,5

The FDA approval of Wegovy was based on the results of the STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial program, which included four phase 3a clinical trials involving approximately 4,500 patients. The trials demonstrated that patients taking Wegovy with a reduced calorie meal plan and increased physical activity achieved a significant reduction in body weight compared with placebo (reduced calorie meal plan and increased physical activity only). In the STEP 1 trial, results also showed that patients taking Wegovy achieved an average weight loss of 14.9% of body weight at 68-weeks vs. 2.4% for placebo. In addition, 83.5% of patients achieved 5% or more body weight reductionin the Wegovy arm vs. 31.1% for placebo.1

The most frequently reported adverse events were nausea, diarrhea, vomiting, constipation, and abdominal pain.1

"This is the first time we have seen this magnitude of weight loss with a medicine. This approval gives people with obesity a once-weekly, non-surgical option with results that have never been demonstrated with an anti-obesity medicine before," said Dr. Robert Kushner, professor of medicine and medical education at Northwestern University, Feinberg School of Medicine, Chicago. "The approval of Wegovy represents a turning point for healthcare providers to embrace medical management of obesity to help improve chronic weight management for patients."

"For more than two decades, Novo Nordisk has led the charge to translate the complex science behind obesity into medicines that can make a difference, all while partnering across industries and sectors to change how obesity is understood, diagnosed and treated," said Doug Langa, executive vice president, North America operations and president of Novo Nordisk Inc. "With the unprecedented efficacy of Wegovy and our innovative, industry-leading pipeline, we have the most significant opportunity yet to drive meaningful change for people with obesity, and the providers committed to their health."

Obesity is recognized as a chronic disease and health issue by leading health organizations, including the American Medical Association, Centers for Disease Control and Prevention, The Obesity Society, and the World Obesity Federation, among other global organizations.3,6-8Obesity has many contributing factors, including genetics, lifestyle and environment.9

"It's remarkable that obesity is still seen as a personal flaw rather than a medical condition requiring treatment, just like any other chronic disease. This disease can negatively impact one's quality of life, both through societal weight bias and stigma, as well as its association with numerous serious health issues," said Joe Nadglowski, president and chief executive officer of the Obesity Action Coalition. "It's time that we recognized this national public health crisis and the need for as many tools as possible to address it. Expanding safe and clinically effective treatment options for obesity management is good news for people with obesity and the medical community."

Novo Nordisk expects to launch Wegovy later this month. For further information, please visit

Wegovy Indication and Important Safety Information

What is Wegovy?

Wegovy (semaglutide) injection 2.4 mg is an injectable prescription medicine used for adults with obesity (BMI 30) or overweight (excess weight) (BMI 27) who also have weight-related medical problems to help them lose weight and keep the weight off.

Important Safety Information

What is the most important information I should know about Wegovy? Wegovy may cause serious side effects, including:

Do not use Wegovy if:

Before using Wegovy, tell your healthcare provider if you have any other medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy may affect the way some medicines work and some medicines may affect the way Wegovy works. Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin. Wegovy slows stomach emptying and can affect medicines that need to pass through the stomach quickly.

What are the possible side effects of Wegovy? Wegovy may cause serious side effects, including:

Please see Prescribing Information including Medication Guide1, 10

About the STEP clinical trial programSTEP (Semaglutide Treatment Effect in People with Obesity) is a phase 3 clinical development program with once-weekly subcutaneous semaglutide 2.4 mg in obesity. The global clinical phase 3a program consists of four trials and has enrolled approximately 4,500 adults with overweight or obesity.1

About WegovyWegovy is a GLP-1 receptor agonist.1 It is currently under review in the European Union and other countries.11

About obesityObesity is a chronic, progressive and misunderstood disease that requires long term medical management.6,12,13 One key misunderstanding is that this is a disease of willpower, when in fact there is underlying biology that prevents people from losing weight and keeping it off.9Obesity is influenced by a variety of factors, including genetics, appetite signals, behavior and the environment.9 It is a gateway disease and is associated with at least 60 other health conditions.4The current COVID-19 pandemic has highlighted that obesity also increases the risk for severe illness and hospitalization due to COVID-19.14-17 The global increase in the prevalence of obesity is a public health issue that has severe cost implications to healthcare systems.18,19 In the United States, more than 42% of adults live with obesity.2

About Novo Nordisk Novo Nordisk is a global healthcare company that's been making innovative medicines to help people with diabetes lead longer, healthier lives for 95 years. This heritage has given us experience and capabilities that also enable us to help people defeat other serious diseases including obesity, hemophilia and growth disorders. We remain steadfast in our conviction that the formula for lasting success is to stay focused, think long-term and do business in a financially, socially and environmentally responsible way. With U.S. headquarters in New Jersey and production and research facilities in six states, Novo Nordisk employs nearly 6,000 people throughout the country. For more information,, Facebook, Instagram and Twitter.


1 Wegovy (semaglutide) injection 2.4 mg Prescribing Information. Plainsboro, NJ: Novo Nordisk Inc.; 2021.

2Adult Obesity Facts. Centers for Disease Control and Prevention. Available at: Updated February 11, 2021. Last Accessed: May 2021.

3About Overweight and Obesity. Centers for Disease Control and Prevention. Available at: Updated April 7, 2021. Last Accessed: May 2021.

4Bays HE, McCarthy W, Christensen S, et al. Obesity Algorithm, presented by the Obesity Medicine Association. Available at: Last Accessed: May 2021.

5Peeters A, Barendregt JJ, Willekens F, et al. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med. 2003 Jan 7;138(1):24-32. doi: 10.7326/0003-4819-138-1-200301070-00008. PMID: 12513041.

6American Medical Association. A.M.A Adopts New Policies on Second Day of Voting at Annual Meeting. Obesity as a Disease. Available at:,c9430649. Last accessed: March 2021.

7The Obesity Society. Obesity as a Disease: The Obesity Society 2018 Position Statement. Available at: Last Accessed: May 2021.

8World Obesity Federation. Obesity as a disease. Available at: Last Accessed: May 2021.

9Wright SM, Aronne LJ. Causes of obesity. Abdom Imaging. 2021;37(5):730-732.

10 Wegovy (semaglutide) injection 2.4 mg Important Safety Information. Plainsboro, NJ: Novo Nordisk Inc.; 2021.

11Novo Nordisk files for EU regulatory approval of once-weekly semaglutide 2.4 mg for weight management. Available at: December 2020. Accessed May 2021.

12Bray GA, Kim KK, Wilding JPH. World Obesity Federation. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation.ObesRev. 2017;18(7):715-723. doi:10.1111/obr.12551.

13Puhl RM, Heuer CA. The stigma of obesity: a review and update. Obesity. 2009;17(5):941-964

14Finer N, Garnett SP and Bruun JM. COVID-19 and obesity.Clin Obes. 2020; 10:e12365.

15Ryan DH, Ravussin E and Heymsfield S. COVID 19 and the Patient with Obesity - The Editors Speak Out.Obesity (Silver Spring). 2020; 28:847.

16Body Mass Index and Risk for COVID-19Related Hospitalization, Intensive Care Unit Admission, Invasive Mechanical Ventilation, and Death - United States, MarchDecember 2020. Centers for Disease Control and Prevention. Updated March 8, 2021. Last Accessed: March 10, 2021.

17Obesity, Race/Ethnicity, and COVID-19. Centers for Disease Control and Prevention. Updated March 22, 2021. Last Accessed: May 2021.

18World Health Organization. Obesity and Overweight Factsheet no. 311. Available at: Last accessed: May 2021.

19Cawley J, Meyerhoefer C, Biener A, et al. Savings in Medical Expenditures Associated with Reductions in Body Mass Index Among US Adults with Obesity, by Diabetes Status. Pharmacoeconomics. 2015; 33:707722.

SOURCE Novo Nordisk

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Novo Nordisk receives FDA approval for Wegovy to treat adults with obesity based on unprecedented efficacy for a prescription medicine in clinical...

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Jun 5th, 2021 | Filed under How to Lose Weight Fast

Protein bars and protein shakes? Nah, eat a fillet of salmon! Fish is one of the healthiest foods you can add to your weekly meal plan. It's rich in all kinds of nutrients that benefit your body in multiple ways, including weight loss. Fish is an essential part of the Mediterranean Diet, which is considered the best diet for weight loss. So it's easy to conclude that eating fish is a huge part of this diet's success.

But how so? How does eating fish help you lose weight? We spoke with a few registered dietitians about how fish can help with your weight loss efforts, as well as other incredible benefits that eating it provides. Here's what they had to sayand for even more healthy eating tips, be sure to check out our list of The 7 Healthiest Foods to Eat Right Now.

"Fish is a great source of complete protein, which is important to help you feel full when trying to lose weight," Jinan Banna, PhD, RDsays. "This can help prevent overeating. A diet that is insufficient in protein may leave you feeling hungry. If your diet is made up mostly of simple carbohydrates, for example, you may not easily feel satisfied. So, rather than consuming a lot of potatoes, white rice, and other such foods as part of your meal, you will want to be sure to consume these moderately and include a serving of protein-containing foods such as fish."

Here's The #1 Best Fish to Eat, According to a Dietitian.

"Fish is a great source of high-quality protein. While protein does a lot of things in the body, from a digestion standpoint, it helps you get full faster and stay full longer," says Amy Goodson, MS, RD, CSSD, LD, author of The Sports Nutrition Playbook. "So, when you add a protein like fish to meals, you're more likely to stay satisfied longer. And if you choose a fatty fish like salmon, trout, or tuna that contains omega-3 fatty acids, you get a double benefit! Fats also contribute to satiety and omega-3s are heart-healthy fats, so it's a win-win!"

Along with fish, here are the 26 Best Omega-3 Foods to Fight Inflammation and Support Heart Health.

"By opting to eat fish over high-fat animal products like beef or pork, you are significantly cutting down on the [number] of calories you're taking in at one meal," says Trista Best, MPH, RD, LD from Balance One Supplements. "Fish can also be prepared in tasty ways without adding excess fat and calorie-dense ingredients like cheeses and creams. Fish is also often paired with nutrient-dense vegetables like asparagus and squash, making the overall nutrient quality of your meals go up while the calorie density comes down."

Not sure how to cook fish at home? Try one of these61+ Best Healthy Fish Recipes for Weight Loss.

Did you know that decreasing your body's inflammation not only helps you to live longer, but also it's linked to weight loss? One study published by the Archives of Medical Science points out that finding ways to "manage obesity" can help reduce the risk of diseases by decreasing inflammation.

"The omega fatty acids in fish will help to decrease the inflammation you are likely experiencing in your body," Best says. "As this inflammation decreases you'll see a change on the scale, but also in your energy. Low-grade, chronic inflammation is linked to mental and physical fatigue. Once your energy has improved you may be more apt to engage in physical activity, which can lead to weight loss."

"Fish is a low-calorie, high protein choice that is perfect for a weight loss plan," Brenda Braslow, MS, RD with MyNetDiarysays. "Per ounce, fish (uncooked) averages about 30 calories. It is one of the lowest-calorie protein foods when compared to other protein sources, such as lean beef at 56 calories per ounce, lean pork tenderloin at 33 calories per ounce, or kidney beans at 36 calories per ounce. Of course, you want to prepare fish without a lot of extra fat. Grilled, baked, boiled, or sushi is very low-calorie. Frying fish or adding rich sauces racks up the calories and won't help you lose weight."

"Protein-rich foods like fish also help keep your blood sugar steady," says Lisa Young, PhD, RDN, author of Finally Full, Finally Slim. "This will help you stay satisfied and keep your calories under control (without you actually having to count calories.) Fatty fish like salmon and tuna have an added boost, as they also contain heart-healthy omega 3 fats which are anti-inflammatory and good for your heart."

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6 Ways Eating Fish Can Help You Lose Weight, Say Dietitians | Eat This Not That - Eat This, Not That

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May 12th, 2021 | Filed under How to Lose Weight Fast
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