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Scientists looking at peptides as a potential tool for muscle development research may be curious about the most practical molecules currently available. Several peptides have been linked to hypothesized properties like the potential increase in muscle cell proliferation and fiber development.

In this comprehensive guide on peptides studied in relation to muscle cells, we have compiled the latest data to aid researchers. This in-depth review covers everything from peptide action mechanisms to potential efficacy and existing research data.

Studies suggest that Sermorelin is one of the smallest functional peptides that may promote the production of growth hormone (GH) by binding to growth hormone-releasing hormone (GHRH) receptors. Sermorelin had regulatory clearance for its effect of boosting GH, an anabolic hormone, which has been suggested to increase growth hormone secretion.

Research suggests that the non-peptide MK-677 (ibutamoren) may mimic the effects of the endogenous hormone ghrelin, much like peptide-based growth hormone secretagogues (GHSs). Researchers are considering it a possible research candidate in the context of growth failure and GH insufficiency. Data suggests it may promote muscle development and lean mass gain, nevertheless.

Investigations purport that Tesamorelin may be an appropriate research peptide in the context of fatty tissue abnormalities in HIV/AIDS research studies; the peptide Tesamorelin has been hypothesized to increase growth hormone release via the gonadotropin-releasing hormone receptors. According to studies, Tesamorelin seems to increase the density and size of muscle cells, which might prevent substantial losses of muscle mass.

Molecules constituted of amino acids linked by peptide bonds are known as peptides. This results in complex molecular structures whose characteristics are determined by their unique sequences of amino acids. Peptides are tiny proteins that usually include two to fifty amino acids.

Their potential role as important cellular communicators, hormone modulators, and growth regulators are only a few of the physiological processes that pique the curiosity of scientists. Artifically synthesized peptides built of sequences of amino acids that often mimic native analogs, have emerged as a result of this.

Synthetic peptides often undergo strategic alterations to improve their selectivity, and potential effectiveness compared to their analogs. Hundreds more are undergoing extensive investigation.

Multiple study peptides have suggested promising results in increasing contractile force within muscles and muscle cell proliferation. Research suggests that certain peptides may promote muscle development by increasing GH synthesis and secretion, affecting insulin-like growth factor-1 (IGF-1) expression. The primary anabolic mediator of GH, IGF-1, is primarily synthesized in the liver in response to GH and then released into the bloodstream. Also, GH may promote IGF-1 production inside muscle tissue in either a paracrine or autocrine fashion.

Increasing muscle protein synthesis (MPS) and decreasing muscle protein breakdown (MPB) are two ways in which IGF-1 might promote muscle anabolism, as suggested by studies:

It is also possible that certain peptides function by interacting with inhibitors or regulators of muscle development. To avoid myostatins restricting effects on muscle development, researchers are looking for peptides such as Follistatin 344. Investigations purport that myostatin inhibitors and other peptides may have complex interactions within the organism, which need further research.

There is promising data that peptides may enhance GH, which might increase IGF-1 levels and promote muscle development. At the moment, this is hypothesized to be accomplished via two related classes of peptides:

Scientists interested in further studying the potential of any of the compounds mentioned in this article may find the highest quality research peptides on the Core Peptides website. Please note that none of the substances mentioned in this article have been approved for human or animal consumption.

Metabolic Profile Studies Involving Peptides - The Teal Mango

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Feb 6th, 2024 | Filed under Sermorelin

CJC 1295 Ipamorelin

CJC 1295 was first made for its medical benefits. It was only later that its growth-boosting uses were found. CJC 1295 and Ipamorelin make more human growth hormone and insulin-like growth factor levels. Ipamorelin affects the Ghrelin hormone too, which is a hunger-stopping hormone. This increase in HGH and IGF, with less hunger, is the start of body change. This mix lets you work your best at the gym without being sore or tired after the session. Even after an injury, the healing time is short. The hormones that have been helped make more muscle mass, less fat, more strength, and more bone density.

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After using these two peptides together, one can hope to get more muscle mass, more strength and energy levels at the best cost, in a way of speaking.

Ipamorelin has a quick effect on the body, while CJC 1295 takes 1-4 hours to reach its best effect. These things have a balancing effect on each other.

Ipamorelin Peptides

It is a peptide that is made in a lab to help human growth hormone production. The ipamorelin peptide is just a helper. It helps human growth hormone production, protein growth, and a change in hunger.

Helping is a great thing; one can use it well by using it well! Less hunger would let you lose fat while more protein growth helps the muscle healing process.

The user must use this by working for it, which may mean spending time during the workout session.

Ipamorelin peptide is called a secretagogue, meaning a thing that makes secretions. With other secretagogues, users have had bad results. For example, cold sweats, trouble sleeping, more anxiety, and bad dreams.

Ipamorelin peptide has no such effect; instead, most users say they sleep longer and deeper with it.

Ipamorelin benefits

Ipamorelin use has many benefits because it makes the brain and other glands in the human body work more.

The following are some of Ipamorelins benefits:

Less fat More muscle mass Better sleeping Muscle and cell repair take less time Less hunger Feeling of newness

Lowers the release of chemicals that may make a fight-or-flight response and those that make oestrogen release

Anti-aging benefits

More bone density

All of these changes are linked exactly to ipamorelin and its effects. Ipamorelin has a good name for power and approval among users, making it a good choice for reaching fitness goals.

Ipamorelin is a growth hormone-making peptide, meaning that it helps in the release of growth hormones. There is a small organ at the bottom of the brain that makes the hormones. Ipamorelin makes this organ, the pituitary gland, work more. Click Here to See Prices

Ipamorelin is one kind of thing that has some fitness and health benefits for these people.

Its very common for bodybuilders and dieters to look for their options in the performance improving drug market. From anabolic steroids to food supplements, they seem to like anything that has a promise.

Here are some examples of peptides for weight loss:

Tesamorelin is a peptide that can destroy fat cells in your body. It is made in the liver and has other benefits. It is good for people who have problems with insulin.

MOTS-C is a peptide that is made in the mitochondria, which are the parts of the cell that produce energy. This gives MOTS-C a lot of power in your body. It increases your energy levels, which helps you exercise more and lose more fat.

Ipamorelin is another peptide that increases your energy levels and helps you lose weight indirectly.

Ipamorelin and weight loss Ipamorelin makes you less hungry by affecting the ghrelin hormone. This is a good thing, but you need to use it wisely. When you take Ipamorelin, you should eat healthy food and exercise. This will make you lose weight faster and better.

Some people have lost 30 to 50 pounds in one cycle of Ipamorelin. This shows how effective Ipamorelin can be. But you need to work hard with Ipamorelin to get these results.

Ipamorelin also gives you more endurance, which means you can do harder exercises. This is where the magic happens: you eat less, you eat well, and you work out hard. All these things make you lose weight and look great."

Peptides for HGH Some treatments use peptides to make your body produce more human growth hormone. The experts who do these treatments use peptides like sermorelin, ipamorelin, isbutamoren, and CJC 1295. These come in small bottles and you need to inject them into your body.

What is Ipamorelin and how well can it help these people, lets see:

Ipamorelin Ipamorelin is a synthetic peptide that is good for bodybuilders and fitness lovers. A peptide is a chain of amino acids, from two to 50 chains. Peptide bonds keep the chain together. At its core, ipamorelin is a synthetic thing that can raise energy levels, make more muscle gains, and lower recovery time.

Ipamorelin is a substance that makes your body produce more growth hormones and proteins. These help your muscles grow bigger and stronger.

Ipamorelin also affects ghrelin, which is a hormone that controls your hunger. When you take Ipamorelin, you feel less hungry and eat less food.

This means that Ipamorelin helps you build muscles and lose fat at the same time. It also makes your muscles look lean and hard, which is what bodybuilders want.

Ipamorelin and HGH Ipamorelin makes your body produce more human growth hormone (HGH). Ipamorelin works directly on the glands that release HGH. When Ipamorelin interacts with these glands, it triggers a response that increases HGH production in your body.

Your body can make HGH on its own, but not as much as when you take Ipamorelin. The difference is very noticeable. The extra HGH improves your health and fitness.

You feel more energetic, focused, and strong when you take Ipamorelin. You can work out better and longer at the gym. You also recover faster after the gym, which helps your muscles grow bigger and healthier. You dont have any pain or soreness after the gym, which makes you more motivated to work out.

Peptides for losing weight Peptides are substances that can do many things for your body. They can help you gain muscles or lose weight. There are special peptides that focus on weight loss.

To get the best results from peptides, you need to exercise and eat well. Peptides can only help you if you do your part.

There are different ways that peptides can help you lose weight. Some peptides increase HGH, which gives you more energy and stamina. This helps you burn more fat when you exercise. Other peptides destroy fat cells directly. This makes your body get rid of fat faster.

Peptides affect how much human growth hormone your body makes. This makes you feel more energetic, focused, and strong. It also lowers inflammation, speeds up healing, and helps you eat better. All these things make you look younger, healthier, and happier.

Ipamorelin dosage The amount of Ipamorelin you need depends on what you want from a cycle. The dosage can change based on your goals. For example, if you want to have big muscles or slim muscles with less fat.

A dosage for big muscles; starting with a low 100 mcg dose, 200 to 450 mcg is a medium dose. On the other hand, a 500 to 600 mcg is a high dose.

The doses affect how fast you see changes. A higher dose would make you see changes sooner, but that could be bad for you.

Every human body is different and flexible. The dosages reflect that; the cycle limit is around 12 weeks, with the beginner dosage around 150 mcg-200 mcg maximum. This would be enough to make you see results and work very hard at the gym.

For a dosage for slim muscles, you need to work harder at the gym, but also eat less. The dosage would be between 100-120 mcg, and the cycle would be a bit shorter than the one for big muscles.

Ipamorelin side effects Like any other chemical, ipamorelin can have side effects. If you dont use it carefully, Ipamorelin could be more harmful than helpful. But, it doesnt have very serious side effects like some other chemicals do.

Ipamorelin is a man-made substance, while sermorelin is a natural one. This means that you cannot take too much Sermorelin by mistake.

They do, however, act very similarly after you take them. And these are some of the effects they have on your body:

stronger bones better concentration healthier heart muscles

You should buy Ipamorelin from its official website, as that would make sure it is genuine. Also, you would get the instructions for the dosage, and some discounts.

Some of its side effects are:

Feeling sick Skin that is itchy or irritated Feeling a tingling in your feet when you sleep Gaining water weight Having a dry mouth

Ipamorelin 1295 before and after It is important to know what to expect before you start the Ipamorelin cycle.

Over the period of a 12 week cycle, you can expect these things:

More strength More energy before working out More lean muscle Faster healing time Less fat

Since Ipamorelin makes your body produce more HGH, you heal faster, have more energy and stamina. HGH also helps make another chemical called Insulin Growth Factor (IGF-1) that helps your muscles grow bigger.

All these chemicals are linked to each other. The process can be very helpful to reach your fitness and body building goals.

Ipamorelin vs Sermorelin According to the research, Sermorelin and Ipamorelin are very similar. The only difference is when you take them and how long they last.

Sermorelin is taken 10 minutes after working out. Sermorelin only lasts for about 12 minutes, yes, 12 minutes!

During that short time, it has the same effects as Ipamorelin. But, you need to take it several times during the day.

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Best CJC-1295 ipamorelin Peptides for Weight Loss | Where To Buy Ipamorelin CJC 1295 Online - Deccan Herald

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Jan 20th, 2024 | Filed under Sermorelin

Two synthetic GHRPs that have received much attention in biochemical studies are Tesamorelin and Ipamorelin. Both Tesamorelin and Ipamorelin have been speculated to have the capacity to increase GH secretion by activating the ghrelin receptor. The peculiar impact of these peptides has piqued the curiosity of the scientific community, leading to a plethora of studies aiming at elucidating their molecular processes and prospective effects.

Tesamorelins potential properties have been studied mostly within the context of metabolic diseases and, more specifically, HIV-associated lipodystrophy. Ipamorelin, on the other hand, has suggested promise in a larger variety of studies, such as those examining its effects on obesity and growth.

This introductory exposition delves into the science behind Tesamorelin and Ipamorelin, highlights their potential synergy, and emphasizes the need for more exploratory study into the pharmacological effects of the two.

Tesamorelin, or growth hormone-releasing peptide (GHRP), is a synthetic peptide having a well-defined amino acid sequence. It comprises a chain of 44 amino acids and seems to work by inducing pituitary secretion of growth hormone (GH).

Tesamorelins possible impact within the context of certain diseases, including HIV-associated lipodystrophy and age-related GH decrease, has been investigated. Although further research is required to definitively evaluate its potential, its hypothesized capacity to increase GH secretion makes it a topic of study in the context of various health-related conditions.

MOD GRF (1-29) is a GHRH analog synthesized in a lab. It was first produced in the 1980s when research suggested that the first 29 amino acids of GHRH may have had all the biological functions normally attributed to the full-length 44-residue protein. The original peptide, GRF (1-29), seems to have all the qualities of the full-length hormone despite being the smallest section of GHRH. Sermorelin, also known as GRF 1-29, is another shortened synthetic version of GHRH with the same number of amino acids. Four substituted amino groups extend the amino acid chains of modified GRF (1-29).

Synthetic peptide Ipamorelin is a member of the growth hormone-releasing peptide (GHRP) family. Alanine, glutamine, histidine, leucine, and arginine are the five amino acids that make up its chemical structure.

The sequence in question seems to provide Ipamorelin, a potentially powerful GH secretagogue, the capacity to increase growth hormone (GH) release by activating the ghrelin receptor. Research suggests that Ipamorelin stands out among GHRPs because it seems to have selective activity with low influence on other hormones, making it a promising research subject for studying how GH is controlled.

Tesamorelin and Ipamorelin seem to have a synergistic impact in the setting of growth hormone insufficiency due to their complex action method.

Researchers have hypothesized that a combination of Tesamorelin and Ipamorelin, given simultaneously, may have a multiplicative impact. Ipamorelin seems to directly stimulate GHSR, while Tesamorelin appears to activate GHRH receptors, both leading to enhanced GH secretion. It is thought that this synergistic effect may enhance GH response as a whole, which may aid things like body composition, lipid profiles, insulin sensitivity, and metabolic function.

Findings imply that Tesamorelin and Ipamorelin may improve pituitary gland activity that eventually enhances the release of endogenous growth hormone by targeting separate components of the growth hormone axis via their respective methods.

In addition to insulin resistance, dyslipidemia, and an increased risk of cardiovascular problems, lipodystrophy is often seen. Experimental studies have suggested that exposure to Tesamorelin to research models of lipodystrophy may improve insulin sensitivity and lipid profiles and may cause a significant loss of visceral adipose tissue (VAT).

Investigations purport that Tesamorelin may promote endogenous growth hormone production and facilitate lipolysis by activating the growth hormone-releasing hormone receptor (GHRHR). Therefore, Tesamorelin may aid in preserving abdominal subcutaneous adipose tissue and bringing about positive changes in lipid metabolism.

Also, Ipamorelin has suggested promise in studies investigating its impact on adipose tissue metabolism. Synergistic impact, which may further amplify the decrease of VAT and improve metabolic parameters in models of lipodystrophy, is postulated about the combined use of Tesamorelin and Ipamorelin.

An ever-expanding body of research suggests that growth hormone and its secretagogues, such as Tesamorelin and Ipamorelin, may have a modulatory impact on neuroplasticity, neuronal survival, and synaptic plasticity, all of which are critical for peak cognitive performance. Tesamorelin has been speculated to improve memory and learning in animal models, presumably via neurogenesis and synaptic plasticity.

Simultaneously, Ipamorelin suggests promise in improving spatial memory and cognition in experimental animal models. There is speculation that the synergistic mechanisms of action between Tesamorelin and Ipamorelin may increase the cognitive properties of their combined presentation. However, further research is required to confirm these results and clarify the biological effects of the mix on cognitive performance.

Positive results from preliminary studies have piqued researchers interest in combining Tesamorelin and Ipamorelin in the context of Type 2 Diabetes Mellitus (T2DM). Scientists hypothesize that both peptides suggest promise in improving glycemic management and reducing metabolic abnormalities related to type 2 diabetes.

Research suggests that improvements in insulin sensitivity and glucose utilization may result from Tesamorelins activity by increasing endogenous growth hormone release. Additionally, it has been purported that Ipamorelin may affect glucose metabolism and insulin sensitivity. Tesamorelin and Ipamorelin may have synergistic effects when combined, including improvements in insulin sensitivity and decreased visceral adiposity in the context of type 2 diabetes, as speculated by professionals.

Tesamorelin & Mod GRF & Ipamorelin blend for sale is available at Core Peptides.


[i] Dhillon S. Tesamorelin: a review of its use in the management of HIV-associated lipodystrophy. Drugs. 2011 May 28;71(8):1071-91. doi: 10.2165/11202240-000000000-00000. PMID: 21668043.

[ii] Gao Y, Yuan X, Zhu Z, Wang D, Liu Q, Gu W. Research and prospect of peptides for use in obesity treatment (Review). Exp Ther Med. 2020 Dec;20(6):234. doi: 10.3892/etm.2020.9364. Epub 2020 Oct 16. PMID: 33149788; PMCID: PMC7604735.

[iii] National Center for Biotechnology Information (2023). PubChem Compound Summary for , Tesamorelin.

[iv] National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 9831659, Ipamorelin.

[v] LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Tesamorelin. [Updated 2018 Oct 20]. Available from:

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Tesamorelin, Mod GRF, and Ipamorelin Blend Research - Fordham Ram

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Nov 19th, 2023 | Filed under Sermorelin

Are you looking to lead an active lifestyle? Whether you want to get stronger, increase muscle function, or just stay in shape, strength, and muscle function are key components of any successful fitness regimen. Strength and muscle function play a major role in our ability to move freely and efficiently throughout daily activities. Not only that, but they also have the potential to prevent injury and improve overall health. In this article, well discuss why strength and muscle function matter for your active lifestyle. Well look at how they help us maintain balance and stability while moving through everyday tasks as well as the benefits of incorporating them into your exercise routine. Well also explore some tips on how best to strengthen muscles safely so that you can reach your goals with minimal risk of injury. So lets dive right in!

One of the most important benefits of strength and muscle function is its ability to improve your balance and stability. This is especially important if youre looking to do activities like running, lifting weights, or even just walking. Strong muscles are necessary for supporting the body in proper form while performing movements. When our bodies are properly supported with strong muscles, it gives us much more control over our movements which decreases our risk of injury. Furthermore, strong muscles can help reduce fatigue during physical activity since they require less energy from the body to move through tasks.

In addition to improving balance and stability, strengthening your muscles can also lead to better overall health. Strong muscles help support our bones, tendons, and ligaments which can reduce the risk of injury or disability. Furthermore, stronger muscles make everyday activities like carrying groceries or climbing stairs much easier on the body since they require less energy output. There is also evidence that strengthening your muscles may improve heart health by increasing circulation and reducing blood pressure levels. For example, a recent study found that lifting weights on a regular basis can help reduce the risk of heart disease. Also, stronger muscles can help improve your posture which is important for avoiding pain and discomfort in the body.

If youre looking to start strengthening your muscles, its important to do so in a safe and effective manner. Here are some tips to help you get started:

Start with low-intensity exercises like walking or light weightlifting using lighter weights. Avoid high-intensity activities until your muscles have had time to adjust to the new routine.

Warm up before any activity by stretching and performing dynamic warmup movements such as squats and lunges. This helps prepare the body for physical activity and prevents injury.

Incorporate rest days into your routine. This allows the muscles to recover and repair between workouts.

Make sure you are eating a balanced diet that is rich in protein, healthy fats, and complex carbohydrates. These nutrients will help fuel muscle growth and repair.

Last but not least, stay hydrated! Staying properly hydrated ensures that the body has enough fluid for optimal performance during physical activity.

The body produces hormones such as testosterone and growth hormone that help to regulate muscle development. Testosterone is primarily responsible for developing strength while growth hormone promotes the synthesis of proteins that are needed for muscle growth and repair. As we age, our bodies naturally produce less of these hormones, making it more difficult to gain or maintain muscle mass. Incorporating activities like weightlifting into your exercise regimen can help stimulate the production of these hormones and promote healthy muscle growth. Additionally, getting adequate sleep is essential for optimizing hormonal production which in turn helps to support healthy muscles.

You can even undergo growth hormone therapy and testosterone replacement therapy if you feel that your levels of these hormones are low. For example, if you are taking Sermorelin then you should make sure you are taking the right Sermorelin dosage to maximize its benefits. Also, your doctor will be able to provide you with other advice on how to optimize the production of these hormones in the body.

Your body needs certain nutrients to build and maintain muscle mass, one of the most important being protein. During exercise, our muscles break down proteins into amino acids which are then used as fuel for your workout. Eating foods that are high in protein can help increase the amount of available fuel your muscles have during physical activity and promote muscle growth afterward. Good sources of protein include meats, fish, eggs, nuts, seeds, legumes, and dairy products. Additionally, supplementing with whey protein can also be a great way to get an extra boost of this nutrient after workouts.

Having more muscle mass can also help boost your metabolism. Your basal metabolic rate (BMR) is the number of calories you need to maintain basic bodily functions like breathing and digestion. Having a higher BMR means that you burn more calories at rest, which can be beneficial for weight loss goals. Additionally, engaging in physical activity regularly helps to keep your muscles active and promotes healthy weight management. This means that the more the muscle mass you have, the higher your metabolic rate will be, making it easier to maintain a healthy weight.

Building and maintaining muscle mass requires a combination of proper nutrition, rest, exercise, and hormone regulation. Eating enough protein is essential for fueling your muscles during physical activity and promoting growth afterward. Additionally, having more muscle mass can help boost your metabolism which makes it easier to maintain a healthy weight. Finally, engaging in activities like weightlifting or undergoing therapies such as testosterone replacement therapy may also be beneficial for optimizing the production of hormones that are responsible for building muscle strength. Ultimately, with the right strategies in place, you should be able to achieve your goals when it comes to gaining lean muscle mass!

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Why Strength and Muscle Function Matter for Your Active Lifestyle - Alvinology

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Apr 26th, 2023 | Filed under Sermorelin

Miami Beach, FL, USA - Miami Beach-based company, Peptide Pros, has recently announced a significant increase in customer interest for their Sermorelin Peptides in the first quarter of 2023. The company is excited about this trend and anticipates the demand to continue to increase.

According to Peptide Pros, the increase in interest in their Sermorelin. Sermorelin is also popular because of its versatility. It can be used in a variety of different clinical trials.

A spokesperson from Peptide Pros stated, "We are thrilled to see such an increase in customer interest in our Sermorelin. This demonstrates the growing awareness of the scientific benefits of HGH and the importance of choosing a reliable source for these types of products. At Peptide Pros, we are committed to providing our customers with the highest quality USA peptides, and we are excited to see more people taking advantage of the sales our products offer."

Peptide Pros is renowned for its outstanding customer service, offering comprehensive support to its customers. The company guarantees delivery in the United States and offers free shipping for domestic orders over $175.00.

The company has earned the trust of its customers with competitive pricing, a great selection of products, and reliable customer support. The company provides a user-friendly eCommerce site using which customers can place orders and track their orders' progress until delivery. Peptide Pros also offers a comprehensive rewards program, discounts, and specials, adding to the convenience of managing their accounts directly from the website.

The increase in customer interest for Peptide Pros' Sermorelin Peptides is a testament to the company's commitment to providing high-quality peptides at affordable prices. With excellent customer service, reliable shipping, and numerous benefits of their products, it is no wonder that Peptide Pros has become the number one supplier of Sermorelin and other USA peptides.

About Peptide Pros

Peptide Pros is a reputable peptide supply company that is headquartered in Miami Beach, Florida. The company has established itself as a leader in the peptide supply industry by providing USA peptides of the highest quality at the lowest possible cost. Peptide Pros offers a wide range of peptides, including Melanotan 2, PT-141, GHRP-6, CJC-1295 and Semaglutide, all of which have at least 99 percent or higher peptide purity. Peptide Pros works closely with its manufacturing partners to ensure the strictest quality control of all the peptides it stocks.

For more information about Peptide Pros or to contact the company, please visit:

Peptide Pros

Media Relations Team


Miami Beach


United States

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Peptide Pros announces increased interest in their Sermorelin Peptides at the beginning of 2023 - EIN News

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Apr 18th, 2023 | Filed under Sermorelin

It was early 2022 when friends here in LA first started sharing their peptide therapy experiences with me. One was on a regimen for fertility in preparation for banking her eggs, another for muscle gains, and yet another for weight loss. The Ozempic controversy had yet to swirl into mainstream consciousness, and I was amazed to hear about their results.

Initially, I spoke with Functional Medicine Nurse Practitioner, Toni Tizon-Damiano of Roots Wellness who offers sermorelin, CJC1295, and semaglutide peptide injections in her practice. Through Toni, I began to learn about the growing promise of peptide therapies to target a wide range of needs from anti-aging to deepened sleep and improved brain health.

As I widened my research, I found that certain top biohackers had been quietly naming peptide injections as an exciting area of progress for years. Insulin, for example, is a peptide and has been around for over 100 years. As is nearly always the case, its taken time and possibly a bit of media controversy for many of the lesser known peptide treatments to become more accessible and better understood.

As the semaglutide (Ozempic) craze has grown, it has triggered valid concerns of a return to diet culture. That craze brought my research to a halt and I hesitated to cover the topic at all. Were on a positive trajectory of body positivity in this decade in a way I hope to see continue.

After polling our readers on Instagram, you let us know that the interest was there, and I decided to publish these insights from three pros, all of whom offer a wide variety of peptide therapies in their practices. Peptide therapies are so promising across an important cross-section of health concerns beyond just weight loss. Across the board, in my look at peptide therapy offerings, Ive found a wide-variety of therapies with claims related to all of the below:

+ Better sleep quality+ Improved immunity+ Improved bone density+ Reduction in body fat+ Increased metabolism+ Increased lean muscle mass+ Accelerated wound healing+ Thicker hair+ Tightening of the skin+ Better athletic recovery+ An overall increase in energy+ Balance with other hormones+ Improved libido and sexual performance+ Improved cognition+ Improved joint pain+ Improved mood

Peptides are not new: A lot of research on peptides has been going on for decades, mostly in Europe, and not the US, acccording to Dr. Jacey Folkers of Joi Womens Wellness, I would assume this is because we have been going through a strong pharmaceutical boom during this time. However, I believe peptides should be a large focus for medicine in the United States moving forward. Unfortunately, Im not confident this will be the case. Hopefully, education and awareness of the benefits of peptides continues to spread so that more and more individuals can experience what they can do for their health and the health of their loved ones.

Were sharing a few of the most notable peptide therapies you should know about below, but first

An important note on Ozempic + Weight Loss:Semaglutide and some other peptides target obesity, appetite control and chronic blood sugar imbalances specifically. While supporting weight loss in obese individuals is key for many preventative health measures, please think twice about any treatment that reduces appetite if medical obesity is not a health issue for you.

Many of us, myself included, actually need more nutrition in our daily diets for optimal health not less. Before approaching any peptide therapy that could effect your appetite, consider working with a nutritionist first to do some personal testing. I recommend long-time TCM contributors Brigid Titgemeier, MS, RDN, LD, IFNCP, holistic nutritionist Kelly LeVeque, and Jennie Miremadi, alicensed integrative clinical nutritionist who also specializes in healing from disordered eating.

Lets start with a few peptides therapies Ive been fascinated to learn more about

SS-31 | According to Dr. Heather Smith-Fernandez of Peptology, SS-31 is a peptide that helps to dysregulate the production of mitochondrial free radical production (mitochondrial-derived ROS) and is therefore being looked as a global anti-aging molecule.

BPC-157 has been experimentally demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments. This peptide has been known to exhibit analgesic (pain relieving) characteristics. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. You can download Peptologys free guide to peptide treatment therapies here.

Cerebrolysin | Also called FPE-1070. The neuroprotective properties of the nootropic peptide Cerebrolysin help to protect neurons from lactic acidosis and prevent the formation of free radicals. Cerebrolysin has been studied in memory loss, concentration decline, Parkinsons Disease, Alzheimers Disease, MS, TBI, and stroke.

CJC1295 | According to Functional Medicine Nurse Practitioner, Toni Tizon-Damiano this growth hormone peptide is one of the most popular peptides used at her practice.With growth hormone peptides, it is important to understand that were not injecting growth hormone itself. These peptides simply enhance the signaling to our pituitary to secrete more of our own supply of growth hormone.

The popular use of growth hormone peptides started after studies found that patients were injecting growth hormone and having negative outcomes. The use of peptides provided some of the benefits of enhancing our own natural supply of growth hormone without the negative side effects

Low growth hormone can cause an individual to feel fatigue, brain fog, depressed, mood changes, low libido, weaker muscle function or a decrease in the ability to gain muscle, an increase in fat and so much more.

Growth hormone is responsible for childhood development, but is also important in adulthood. Growth hormone is responsible for many functions in our body that we lose as we age. After age 30, there is a steady decline of growth hormone produced by our body. This decline is often due to aging but also to toxin exposure, oxidative stress, disease, lack of sleep, obesity, inflammation and of course, chronic stress.

DSIP or Delta sleep-inducing peptide | According to Dr. Jacey Folkers of Joi Womens Wellness, DSIP is a naturally occurring substance originally isolated from rabbit brains in 1977. DSIP has been described as a sleep-promoting substance rather than a sedative. Clinical uses for DSIP exist and the peptide has been used for the treatment of alcohol and opioid withdrawal with some success.

Semaglutide (Ozempic, Wegovy) | Semaglutide is a GLP-1 peptide (glucagon like peptide receptor agonist), says Nurse Practitioner, Toni Tizon-Damiano. Semaglutide has been prescribed for those with type 2 diabetes to help lower hemoglobin A1C (3 months blood sugar). These patients found that they were not only lowering their A1C, but also losing weight. Semaglutide helps to increase insulin secretion to decrease blood sugar in turn, decreasing appetite. Many of my clients are experiencing faster weight loss, lower cholesterol, lower hemoglobin A1C and potentially lowering their risk for cardiovascular related deaths.

Semaglutide was first developed in 2012 with 1 mg injection (Ozempic) first approved as a treatment for type 2 diabetes in 2017. The FDA approved semaglutide in 2021 for chronic weight management in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol).

Selank | This peptide has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and anti-stress drug that relieves aggression and fear reaction in different animal species. Selank also has a nootropic action, which promotes the formation of memory and learning processes, and tremendous immunomodulatory activity.

Sermorelin is a peptide analogue of growth hormone-releasing hormone. It was first developed within the United States during the early 1980s. By 1997, the FDA approved its use and sale via prescription.

Yes, peptides have been around and researched much longer than most people realize. Sermorelin acts in a very specific way and is valued for its therapeutic possibilities. It does not affect the levels or actions of glucose, insulin, prolactin, cortisol, thyroid hormones and a host of other compounds within the body. Instead, sermorelin stimulates the body to increase its production of human growth hormone which improves the efficiency of the bodys metabolism. Because Sermorelin increases the bodys metabolism and improves energy levels, it has also been shown to have a beneficial effect on weight loss in people who want a more natural approach.

We also asked Dr. Jacey Folkers to weigh in further on the controversies surrounding semaglutide, from reduced access to diabetes meds, the narrative around weight loss culture even Ozempic face. He shared this with us:The latest data shows that over 73% of US adults are overweight or obese with obesity as the leading risk factor for type 2 diabetes. Whats more, cardiovascular disease remains the leading cause of death in America.

Both obesity and diabetes mellitus are important independent risk factors for the development of cardiovascular disease. We tend to categorize people based on official diagnoses, but just because a person struggling with weight or obesity has not been diagnosed as a diabetic does not necessarily mean they do not have the same health risk factors as a person who has. Medication that can help prevent and even reverse the chronic metabolic conditions that lead to diseases linked to diabetes and obesity should not necessarily be limited to one specific diagnosis.

Semaglutide can dramatically change the trajectory of a persons health by helping improve the metabolic and blood sugar imbalances many Americans have. For the most part, type 2 diabetes and obesity are conditions with significant lifestyle contributing factors. Semaglutide can help people make changes in their lifestyle that will benefit their health. It can help excess weight come off and blood sugar levels to improve, which can lead to overall better health.

When it comes to the discussion around Ozempic face, this side effect should not be blamed on the medication itself. When dosed appropriately, semaglutide can help facilitate a steady and gradual weight loss experience for many patients. With all medications, the dose is extremely important, as everyone responds to medications a bit differently. If a patient is being monitored well and dosed appropriately, their weight loss can be managed at a more gradual rate and prevent extremely fast drops in body mass, which can lead to Ozempic face.

Overall, peptides have far less side effects compared to pharmaceutical medications. Peptides have a pleiotropic effect (more than one effect) on the body and functions in the body in a more natural way. Medications often are meant to have a single direct effect and change or inhibit a naturally occurring pathway in the body. For example a COX2 inhibitor has a single targeted inhibition, and because of that, we get a whole bunch of side effects. The medication is forcing a response to occur in the body, whereas a peptide will moreso guide the bodys own built-in healing process to function better.

Tizon-Damiano notes that growth hormone peptides specifically are not safe for anyone that has a known cancer and have not been well studied in those with thyroid disorders. I require lab testing, vital signs, weight and BMI. Monitoring Insulin like growth factor (IGF-1) and other basic labs are crucial. IGF-1 is a biomarker that is the most important at mirroring what our growth hormone is doing. It has been studied in aging and the key is not to be too high or too low but to be balanced.

I urge people to commit to their peptide regimen for the full 6 months and then cycle off at least 30 days between to make sure that the body will continue to produce its own natural supply of growth hormone and wont develop resistance to it.

Tizon-Damianos patients most often see results in 3-6 months after daily injections that must be kept in the refrigerator. Side effects from peptide injections can include nausea and/or dizziness that commonly diminish once the body adjusts to the peptide.

The needles involved in peptide injections are very small, nonetheless most of them require injecting 5 out of 7 nights per week on an empty stomach.

Peptide injections usually range from $150-$300 per month depending on the peptide.

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6 Peptide Therapies According to Pros - What You Should Know - The Chalkboard Mag

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Generic name: sermorelin acetate [ser-moe-REL-in-AH-seh-tate]Brand name: Geref

Diagnosing and treating growth hormone deficiency in children. It may also be used for other conditions as determined by your doctor.

Sermorelin acetate is a growth hormone-releasing agonist. It works by stimulating the pituitary gland to release growth hormone.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with sermorelin acetate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with sermorelin acetate. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if sermorelin acetate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Use sermorelin acetate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use sermorelin acetate.

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Facial flushing; headache; nausea; pain, redness, or swelling at injection site; paleness; strange taste in mouth; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at .

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in heart rate and blood pressure.

Store sermorelin acetate in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep sermorelin acetate out of the reach of children and away from pets.

This information is a summary only. It does not contain all information about sermorelin acetate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: June 3, 2015

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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Sermorelin acetate: Indications, Side Effects, Warnings -

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Feb 7th, 2023 | Filed under Sermorelin

Effective treatment of adult-onset growth hormone insufficiency: Sermorelin is an effective and attractive treatment of adult-onset GH insufficiency. Unlike rhGH, sermorelin does not stimulate IGF-1 production in the liver and instead stimulates the pituitary gland to produce and secrete endogenous hGH, giving it a number of clinical advantages over exogenous hGH.

Notably, according to a 2006 article by Richard Walker, overdoses of endogenous hGH are difficult if not impossible to achieve as the effects of sermorelin are regulated by negative feedback involving the inhibitory neurohormone, somatostatin.

Sermorelin is not associated with the pro-cancer and pro-diabetes side effects linked to long-term hGH therapy, and is thus heavily researched to treat adult-onset GH insufficiency along with being used in longevity medicine for preserving youthful anatomy and physiology [5].

Positive effects on body composition: Sermorelin has been identified as one of several growth hormone secretagogues (GHS) that can help manage body composition in hypogonadal males. In a 2020 paper, Deepankar et al. noted that sermorelin can significantly improve body composition (in hypogonadal males) while ameliorating specific hypogonadal symptoms such as fat gain and muscular atrophy [6].

While the authors suggest that sermorelin could be used to achieve lean mass gain in both hypogonadal males and men with subclinical hypogonadism, to date, there is no published research that has investigated sermorelins effect on body composition in healthy subjects, highlighting an area for further research.

Potential anti-aging benefits: A 1992 study identified sermorelins potential anti-aging benefits after nine young male test subjects (22 to 33 years old) and ten elderly male test subjects (60 to 78 years old) were administered the peptide. The study found that short-term subcutaneous sermorelin injections enabled healthy male test subjects to reverse age-related decreases in GH and levels of IGF-I [7].

A 1997 single-blind randomized placebo-controlled trial found that elderly male and female test subjects who received nightly subcutaneous injections of sermorelin for 16 weeks experienced a significant increase in skin thickness. The peptide was found to produce significant increases in lean body mass in male test subjects and notable increases in libido and wellbeing. Male test subjects gained an average of 1.26 kg of lean body mass by the end of the trial [8]

Sermorelin and heart health: Sermorelin has been investigated alongside other GHRH agonists as a potential treatment for myocardial infarction scarring in swine [9]. The 2015 study found that sermorelin offered a number of benefits in post-heart attack animal models, which included:

As a result, there is research interest in sermorelins heart health-related benefits, namely in its potential to treat problems resulting from cardiac remodeling and ability to heal damage in myocytes following a heart attack.

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Sermorelin | Reviews, Dosage & Clinical Trials - Peptides

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Jul 25th, 2022 | Filed under Sermorelin

Our bodys size, health, and overall composition are largely determined by its ability to produce growth hormones, which are generated from the anterior pituitary gland, a tiny gland at the base of the brain. One of these hormones is thehuman growth hormone(HGH), which facilitates growth in children and maintains organ and tissue health throughout ones life. However, as we get older (or, in the case of certain disorders, from childhood), our bodys ability to produce HGH diminishes, resulting in some of the changes we commonly associate with the aging process.

To that end, there has been a large interest in using synthetic HGH to stave off the aging process, which can ostensibly help maintain muscle and bone mass even into middle age and our later years. While HGH is often available for those suffering from specific childhood growth hormone deficiencies, it is becoming more common in adult therapies as well.

Despite this popularity, there are a number of concerns about the use of synthetic HGH in hormone replacement therapies; to that end, many patients consider hormone therapies involving sermorelin acetate as a safer, more ethical replacement.

Sermorelin acetate, or factor 1-29 NH2acetate, is a growth hormone releasing hormone (GHRH) naturally produced by the brain. Its goal is to encourage the pituitary gland to produce and secrete human growth hormone (HGH). Its not a growth hormone by itself, but instead a growth hormone secretagogue, a separate hormone that stimulates the production of HGH by binding specific receptors to increase HGH production and secretion.

When we are young, our bodies produce sermorelin acetate, allowing our pituitary gland to facilitate the production of HGH. HGH has theeffectof regulating body composition and fluids, as well as facilitating muscle and bone growth, increasing metabolism and improving heart function. In order to produce the levels of HGH required to grow and maintain healthy brain and organ tissue, the body must produce equivalent levels of sermorelin acetate to facilitate its production in the pituitary gland.

HGH is extremely important to human beings during childhood, as it facilitates the growth that occurs during the first twenty years of our lives. As with other hormones like testosterone, the human body typically produces the highest amounts of sermorelin acetate during puberty, leveling off in their twenties and beginning to slowly but steadily diminish once a person enters their thirties and forties. Older men tend to be more likely to suffer from lower levels of sermorelin acetate, as the aging process has slowed down the bodys production of the hormone.

As men age, they can be more likely to suffer fromadult-onset growth hormone deficiency(AGHD), a phenomenon characterized by a relative increase in fat mass, and a commensurate decrease in muscle mass. Sufferers also experience lower energy levels, anxiety and depression. Furthermore, AGHD sufferers also have maladjusted lipid levels, raising their levels of LDL-cholesterol and triglycerides.

Overall, as HGH levels begin to slow down as we get older, we begin to experience the effects commonly associated with aging. These include weight gain, lower muscle mass, lower bone density, insomnia, and changes in our own personality and self-regard. Many different metabolic changes begin to occur, which can lead to greater risk for heart disease, diabetes, metabolic syndrome. These relate closely to many of the common causes of death for people over fifty years of age.

Unlike other hormones like testosterone, sermorelin has an extremely short half-life approximately eleven to twelve minutes after administration, most sermorelin is rapidly cleared from circulation. Most adults have aclearance valueof 2.4 to 2.8 liters per minute (L/min).

There are a number of factors that can contribute to the onset of AGHD:

When the human body fails to produce sufficient levels of sermorelin, the pituitary gland is not motivated to produce HGH, leading to the following side effects:

While these physiological symptoms can have an effect on your physical health, having AGHD corresponds with real, practical deficits in your everyday life:

As we get older, our physical appearance begins to change in ways we often cant expect and do not want. However, by encouraging the stimulation of HGH, we can safely and effectively stave off those effects and increase our quality of life.

Growth hormone stimulationtherapy (GHST) is a regimen that involves administering supplements of sermorelin acetate into the body as a replacement for the bodys natural production of the hormone. This is particularly useful for people who experience lower than usual levels of sermorelin production, as well as those who would like the benefits of HGH without taking it directly.

Sermorelin therapy is simple, especially when thoroughly supervised by a wellness professional. Patients are given a prescription of a multi-dose, injectable vial, which contains a powder disk containing sermorelin acetate. The powder combines with bacteriostatic water to form the solution found in the injectable vial.

Mostsermorelin therapy regimensinvolve the patient self-administering a dose into the body fat, just under the skin with a small needle. Most regimens will involve injecting you with more frequent doses of sermorelin at the beginning of therapy (known as a loading period), then tapering off over time. Sermorelin encourages drowsiness since growth hormones are typically released by the body when were asleep; its recommended that patients take their doses right before bedtime.

When this sermorelin is administered into the body, it goes to the pituitary gland and binds to the appropriate receptors, encouraging the pituitary gland to produce greater amounts of HGH. Given this added stimulation, the pituitary produces more HGH than a body suffering from AGHD or otherwise diminished growth hormone production would normally make. This encourages the kind of health and physiological benefits that come with the HGH levels of a younger person.

While there are absolutely instances of people directly taking HGH to improve their overall strength and well-being, especially athletes and older people hoping to minimize the effects of the aging process. However, the use of this therapy isextremely controversial, as there have been noted reports of serious side effects in some patients. The Code of Federal Regulations, for instance, prohibits the use of HGH in adults, save for some special cases like those suffering fromdwarfism or AIDS.

Some concerns about the direct application of HGH therapy include the mitogenic nature of the hormone, which may awaken latent cancers or lead to diabetes and other disorders. Other potential side effects include early development of carpal tunnel syndrome, increased resistance to insulin, edema (swelling of the arms and legs), muscle and joint pain, and gynecomastia in men. While research is still pending on the long-term effects of HGH therapy, it is generally considered to be fairly risky and not worth pursuing.

However, with sermorelin therapy, the only HGH being produced is that generated naturally by the bodys pituitary gland. All the treatment does is increase the levels of GHRH in the body, thus signaling to the body to synthesize HGH on its own. This side-steps many of the potential side effects and long-term potential problems of HGH therapy, while achieving similar results. By motivating the body to produce HGH on its own, sermorelin therapy is generally considered safer and more ethical.

Semorelin therapy is perfectly safe and healthy, particularly when a regimen is supervised by wellness professionals, in conjunction with recommended lifestyle changes such as diet and exercise.

Synthetic sermorelin has existed for quite some time on the commercial market as an alternative to the synthetic rhGH, meant to treat stunted growth in children; however, it is much better suited to use in adult anti-aging therapies (and far safer than HGH) for thefollowing reasons:

In short,sermorelin therapyis a much safer and preferable alternative to HGH therapy, particularly for older patients. Rather than risking the potential side effects of HGH, including overdose and building up a resistance to the hormone, GHST simply encourages the body to increase more of what it naturally produces.

If sermorelin therapy is something you would like to get involved with, the best plan is to seek outwellness professionalsthat specialize in anti-aging hormone therapies, particularly sermorelin treatments. With their help and supervision, you can begin an effective regiment of sermorelin therapy, in conjunction with properdiet, exercise, and other lifestyle changes.

If you live in either of these areas, we offer testosterone replacement therapy in Miamiandtestosterone replacement therapy in LA.

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Sermorelin 101: What Is Sermorelin? | Sermorelin Side Benefits & Side ...

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Jul 25th, 2022 | Filed under Sermorelin

Researchers interested in experimenting with sermorelin may be curious about the best way to administer this peptide. This sermorelin dosage calculator and guide draws upon past research and summarizes the doses used in previous sermorelin studies. By consulting this data, peptide researchers may gain an insight into how to dose sermorelin in future experiments and trials.

For researchers unfamiliar with sermorelin, this guide will also offer a complete overview of the benefits and side effects associated with this compound and any statistically significant benefits observed in past research.

Those interested in pursuing sermorelin research can find details of our preferred peptide vendor at the end of this guide. This vendor can ship research-grade sermorelin to researchers worldwide and come highly recommended.

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Disclaimer: contains information about products that are intended for laboratory and research use only, unless otherwise explicitly stated. This information, including any referenced scientific or clinical research, is made available for educational purposes only. makes every effort to ensure that any information it shares complies with national and international standards for clinical trial information and is committed to the timely disclosure of the design and results of all interventional clinical studies for innovative treatments publicly available or that may be made available. However, research is not considered conclusive. makes no claims that any products referenced can cure, treat or prevent any conditions, including any conditions referenced on its website or in print materials.

Sermorelin acetate is a peptide made up of a chain of 29 amino acids. It is commonly referred to as sermorelin and was previously sold under the brand names Geref and Gerel. It is synthesized to resemble endogenous growth hormone-releasing hormone (GHRH) [1].

Sermorelin works by interacting with the bodys endocrine system. Since it resembles endogenous GHRH, it produces a similar effect, which is to bind to receptors that tell the pituitary gland to release more growth hormone into the bloodstream.

The result? Growth hormone (GH) levels increase.

What is growth hormone? An essential part of the bodys tissue construction process.

Growth hormone, also called human growth hormone (HGH), is involved in many biological functions including the reproduction of cells and the repair of tissue [2]. Because GH is so important for the growth and repair of tissue, there is currently strong research interest in the extent to which HGH may improve body composition and performance.

However, administering exogenous HGH directly to test subjects can produce a range of serious side effects, including swelling, joint pain, carpal tunnel syndrome, and an increased risk of diabetes [3]. It may also increase the risk of certain types of cancer, such as Hodgkins Lymphoma [4]. These risks mean that HGH research is strictly regulated and tightly controlled.

Thats the beauty of sermorelin research.

Rather than administering HGH directly, researchers can use sermorelin to increase HGH levels in test subjects by naturally stimulating the pituitary gland to release more endogenous HGH. Instead of spiking HGH to supraphysiological levels, sermorelin is believed to produce a gradual increase in HGH in a stable, predictable way.

In the next section, well take a look at the main benefits and uses of sermorelin.

So, what are the Sermorelin benefits? Well, there are quite a few.

In 1997, sermorelin received U.S. Food and Drug Administration (FDA) approval for the treatment of growth hormone deficiency (GHD) in child and adult patients. It was available under the trade name Geref and was also used as a diagnostic agent to check pituitary gland function.

However, the USFDA withdrew approval for Geref in 2008 and it was subsequently discontinued. While the manufacturer stressed that this was for reasons unrelated to safety or efficacy, the simple fact is that sermorelin no longer has any recognizer therapeutic use. In other words, it is a research chemical and is not approved for human use.

As sermorelin is able to increase GH levels in human test subjects, there is strong interest among peptide researchers as to whether it may offer the following benefits:

In summary, while sermorelin is a research chemical and no longer has FDA approval, ongoing research indicates that it may offer a wide range of benefits. Hopefully, researchers interested in exploring sermorelin can consult the relevant literature when calculating sermorelin dosage.

Well now explore the documented sermorelin side effects.

Sermorelin appears to offer several benefits, but are there any sermorelin side effects?

Firstly, researchers need to know that the decision to withdraw sermorelins FDA approval was for reasons other than safety or efficacy. There is no research to date that has linked sermorelin to any clinically significant adverse effects in test subjects.

In general, sermorelin is considered by most researchers to be well-tolerated by test subjects [12]. Side effects from sermorelin administration are rare and not severe. Some of these more mild side effects include:

More rarely, some test subjects have reported the following side effects:

To minimize the risk of test subjects experiencing side effects as a result of sermorelin administration, researchers are advised to consult the relevant literature when designing an experiment.

In the following section, well outline how this research chemical has been used in past studies.

Researchers interested in working with sermorelin may use this sermorelin dosage calculator during the design and planning phases of the research process. Below, the main doses used in past sermorelin studies are highlighted along with any general guidance that researchers may need to be aware of.

Sermorelin acetate usually comes in powder form. Prior to administration, researchers must first reconstitute it with bacteriostatic water by injecting water with a large mixing syringe against the glass wall of the vial. This water must be swirled, gently, around the vial until all of the powder is dissolved.

Researchers should follow the directions for how much water to add. For a 15 mg vial of sermorelin acetate, 7.5 ml of bacteriostatic water is typically required. Note that 10 units on an insulin syringe usually equates to 200 mcg of sermorelin.

Reconstituted sermorelin must be refrigerated and kept away from heat, light, moisture. It can be stored for up to 90 days. Researchers are advised to discard any sermorelin that is cloudy or contains particles.

When sermorelin held FDA approval as a treatment for GHD, it was administered intravenously as a subcutaneous injection. However, sermorelin may also be administered into the muscle as an intramuscular injection.

In terms of the timing of these injections, sermorelin has been administered to test subjects In past studies at night, at least two hours after eating. As HGH levels naturally peak at night, this protocol is believed to enhance HGH secretion.

During the period when sermorelin held FDA approval and was used to diagnose idiopathic GHD in children, it was administered intravenously at a dose of 1mcg per kilogram of body weight.

To date, sermorelin has not been approved for any other purpose and is currently classified as a research chemical. Therefore, based on the available data, researchers interested in experimenting with sermorelin for its purported recovery benefits may administer it in the following way:

While there is strong research interest in the application of sermorelin to improve the appearance of skin and reduce body fat, there is no published research to indicate the dosage at which it may be administered to this end.

Researchers interested in experimenting with sermorelin may consult the available literature regarding the past use of sermorelin as a treatment for GHD. This research indicates that a dose of 1mcg/kg of body weight provides a clinically significant effect in test subjects.

As with anti-aging and weight loss, there is currently very strong research interest in the application of sermorelin to lean muscle increase and athletic performance in test subjects. However, to date, no research has been published to indicate the dosage at which sermorelin may be administered for this purpose.

Based on the available data, doses of 1mcg/kg of bodyweight appear to produce a discernible effect. Researchers interested in exploring these purported benefits of sermorelin may consider this as a starting dose for any experiment they decide to conduct.

Researchers interested in experimenting with sermorelin should note that while this peptide has previously held USFDA approval as a treatment for GHD, it is currently classified as a research chemical and has no recognized therapeutic use.

The best place to buy sermorelin online is Peptide Sciences, a U.S.-based company that provides high-quality, research-grade peptides without additives or fillers.

We love Peptide Sciences because they have a solid track record and get every batch of peptides tested by an independent lab before putting them up for sale.

Here are a few things they do exceptionally well:

Researchers interested in exploring the benefits and side effects of sermorelin may consult Peptides Sciences to discuss their needs.

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Hopefully, this sermorelin dosage calculator and guide has provided a useful starting point for researchers interested in working with this peptide. Although sermorelin is no longer FDA approved, past research findings indicate that further research may be warranted, especially with regards to GHD treatment, long-term safety, and anti-aging effects.

Those interested in finding a reliable, trustworthy sermorelin vendor may consider contacting our preferred supplier, Peptide Sciences.

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Sermorelin Dosage Calculator and Guide | What You Must Know

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Jun 17th, 2022 | Filed under Sermorelin
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