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Greateruse of testosterone therapy (TTh) is associated with a lower risk for prostatecancer (PCa) in men without diabetes, according to study findings published in Clinical Endocrinology.

Of189,491 men ages 40 to 60 years in the IBM MarketScan Commercial Database whoreceived testosterone therapy, 1424 were diagnosed with PCa. Among men withoutdiabetes, those who received more than 12 testosterone injections had a 33%lower risk for PCa than men who received only 1 to 2 injections, in adjustedanalyses, David Lopez, DrPh, MPH, MS, of University of Texas Medical Branch at Galveston,and colleagues reported. Likewise, men with more than a 330-day supply oftestosterone gel had 45% lower risks for PCa than men with a 60-day supply orless. The investigators found no significant association between testosteroneuse and PCa in men with diabetes.

Since their resultsshowed a significant inverse relationship between TTh and PCa only amongnon-diabetics, we could hypothesize that diabetes has a stronger effect onincreasing probability of PCa than the beneficial effects of TTh, Dr Lopezsteam wrote. Therefore, diabetes overwhelmed the beneficial effects provided byTTh use on reducing the association with PCa among diabetics and thus no statisticalassociation was found in this group. Yet, this latter statement is onlyhypothetical.

Theinvestigators adjusted for age, Charlson Comorbidity Index, PSA, hypogonadism,diabetes, hypertension, malaise and fatigue, osteoporosis, testiculardysfunction, erectile dysfunction, depressive disorder, anterior pituitarydisorder, decreased libido, and use of insulin and statins but not race or bodymass index, which is a limitation.

Reference

Lopez DS,Huang D, Tsilidis KK, et al. Association of the extent of therapy with prostatecancer in those receiving testosterone therapy in a US commercial insuranceclaims database [published online September 9, 2019]. Clin Endocrinol. doi:10.1111/cen.14093

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Can Testosterone Therapy Lower Prostate Cancer Risk? - Renal and Urology News

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Sep 18th, 2019 | Filed under Testosterone

DEAR DR. ROACH: Im an 81-year-old man. About two years ago, I began to realize that my testicles were shrinking, and they are now about the size of a marble. I have asked my primary care doctor and urologist about this, and the reply is that nothing can be done about it.

I have read that boxer shorts are recommended to keep the testicles cooler and healthier. I am wondering whether my extensive time sitting at a desk and reading could be related to my shrinking testicles. Or is it related to erectile dysfunction, which is caused by decreased blood flow? I have ED. My last testosterone result was about 500. Is there nothing that can be done, not even any exercises? L.D.

ANSWER: The medical term for whats happening to you is testicular atrophy, and it has several possible causes. Age alone is one: At age 81, many men have noticed some shrinkage in testicular size, but yours is beyond the norm. You are right that cooler temperatures are healthier for the testicles, but again, I am a little surprised by the severity of your description.

Among the other common causes are a history of trauma or infection. However, any underlying cause can also affect the ability of the testicles to make testosterone. Your blood testosterone level is surprisingly normal for your age (400-500 is the average for a man in his 80s). A low testosterone is a common cause of erectile dysfunction (poor blood flow is only one cause of ED).

After two years, it is very unlikely that any treatments will affect the testicles now, unfortunately.

DEAR DR. ROACH: Im a 91-year-old male who makes frequent visits to the bathroom to urinate. I am in good health and I wonder what causes this. Where does all that liquid come from? A.R.N.

ANSWER: What goes in must come out. All the liquid you urinate came from fluid you consumed when drinking and eating food.

But it may be more about perception than volume. Frequent urination is extremely common in both men and women, and although some causes are the same, such as an overactive bladder, men have an additional anatomical structure that can lead to urinary problems as they get older: the prostate, a normally walnut-sized gland that may increase in size as men age. It is through the prostate that the urethra, and thus all the urine, has to flow. If the prostate is enlarged, the urinary flow slows down.

As the prostate obstruction becomes worse, men may have trouble emptying the bladder completely. This has the effect of making men go to bathroom more frequently, since the bladder has less functional size. In this case, you arent urinating any more volume than before, just more often in smaller amounts.

Treatment needs to be directed at the underlying cause. Overactive bladder and enlarged prostate have similar symptoms and different treatments.

It is possible that you really are having excess volume, however. Diabetes is the biggest concern here, and you should be tested if you have truly large volumes of urine.

Dr. Keith Roach is a syndicated columnist.

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A question of shrinkage - Clinton Herald

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Sep 18th, 2019 | Filed under Testosterone

He was a double Olympic gold medalist, but Sebastian Coe's legacy in athletics will perhaps be defined by his handling of the two great modern issues in the sport -- the case involving Caster Semenya and doping.

As president of the International Association of Athletics Federations (IAAF), Coe's actions and those of the organization could have long-lasting effects on generations of athletes, including Semenya.

The 28-year-old South African has been barred from defending her world 800-meter title in Doha this month for refusing an IAAF ruling to take testosterone-reducing medication.

The two-time Olympic champion, who is hyperandrogenous and has increased levels of testosterone for a woman, has become the center of a storm around athletes with a difference in sex development and human rights.

However, Coe admitted to CNN World Sport's Amanda Davies that despite the high profile nature of the case he hadn't spoken to Semenya directly.

"Have you spoken directly to Caster Semenya?" Davies asked Coe.

"No," the IAAF president replied. "And I haven't because this is not about an individual athlete.

"It's not about a particular country. It's not about a particular continent. I don't see this as a personal issue. I see this as the right decision and those regulations have been tabled for what I believe are the right reasons."

READ: Christian Coleman: Athletes criticize 'loophole' after sprinter avoids ban

READ: Seb Coe: IAAF chief says Russia must make major anti-doping changes

But does he have any sympathy for Semenya, an athlete who has not been convicted of doping but who has been denied the freedom to compete because of a rare genetic condition?

"I have clearly a sympathy for the efforts we are trying to make," said Coe. "I hope she does come back on to the track and I do hope that the athletes with that condition to take the medical direction that allows them to do that."

The issue of doping has also been on the agenda of the IAAF recently after 23 year-old American sprinter Christian Coleman missed three drug tests in the space of a year, but has avoided suspension under the World Anti-Doping code, and will compete in Doha.

Coe was asked if missing three tests in 11 months was acceptable.

"Well, look, look," Coe said before calling the whereabouts rule -- which stipulates athletes must provide their anti-doping organization with details of where they can be found for one hour every day for potential testing -- a "really important part of the landscape in that no athlete should be cavalier or coy about."

"The one thing I'm very proud about in our sport is we don't shirk the difficult issues," Coe explained. "Very few big organizations wanted to take the lead role in the challenges around around DSD (disorders of sex development).

"Transgender is going to be a massive issue. I want athletics to always be at the forefront of thought leadership. That isn't an easy position to be in, but it is the right position to be in. I'm happy that our sport is brave enough to want to challenge these issues and take them head on."

While Semenya won't be on the track in Doha. Coleman will be and is the bookies' favorite to claim the men's 100m title, ahead of convicted doper Justin Gatlin.

The two American sprinters are standout figures in a field lacking in household names. Usain Bolt ran his last race in 2017 and Wayde van Niekerk -- reigning 400m world champion -- continues to miss out with a recurring knee injury.

In the women's sprints Shelly-Ann Fraser-Pryce and Dina Asher-Smith willl attract attention, but is a lack of star-quality elsewhere a concern for Coe?

"In my lifetime, I don't remember being more excited about the current batch [of young athletes] that are coming through," said Coe.

"If you take all our disciplines, the top 10 in those disciples, a quarter of them are under the age of 22 to 23. That's a fantastic position to be in and we will have some amazing names emerging."

READ: Caster Semenya begins 'new journey' at football club

READ: Caster Semenya blocked from competing at World Championships

Coe continued: "We've got a new generation coming through that are communicating well. They're good at this and our sport is in much better shape.

"I cannot think of a time when I've been more optimistic about the future of my sport because of their quality and their confidence that we're in their corner. That we're putting systems in place that are going to protect them."

The IAAF didn't provide details of what level of protection or what duty of care, each individual athlete will receive.

Coe also spoke on the importance of filling stadiums, on keeping sponsors on board, on attracting a new fan base and reaching a new audience through innovative technologies.

He added that he was excited to do "some of the fun stuff now," having laid down the "foundation stones" during his first period as president.

But as new challenges arise -- the reintroduction of Russia after allegations of state sponsored doping that saw 67 athletes banned by the IAAF in 2016, as well as the the organization's role in combating climate change, to name but two -- Coe will appreciate that his organization still has much to do

The World Championships begin on September 27. For 10 days, Coe will hope that conversations stay on the track and a clutch of new fan favorites usher in a new era.

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'I don't see this as a personal issue,' says Seb Coe on Caster Semenya case - Action News Now

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Sep 18th, 2019 | Filed under Testosterone

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Testosterone Replacement Therapy Market has Huge Growth in Industry|Endo International, AbbVie, Eli lilly, Pfizer - Tribune City

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Sep 18th, 2019 | Filed under Testosterone

Cognitive empathy is the ability to recognize what another person is thinking or feeling, and one way it can be assessed in the lab is by using the reading the mind in the eyes test or eyes test, for short. This involves looking at photos of a persons eyes and picking which word best describes what the person in the photo is thinking or feeling.

Many studies, including our own, have shown a link between elevated testosterone and reduced cognitive empathy. But a new study led by Amos Nadler, a visiting professor of economics at the University of Toronto, found that administering testosterone to men does not reduce their empathy, as measured by this test.

Nadler and colleagues also measured digit ratio. The ratio between the length of a persons index and ring finger is thought to be an indicator of how much testosterone they were exposed to in the womb (prenatal testosterone levels), and has also been tied to a lack of empathy. Nadler and colleagues study found that digit ratios were not related to empathy scores.

From these findings, they draw two conclusions: first, that this disproves a previous study by Jack van Honk and colleagues in which administering testosterone to women reduced their empathy. And second, that prenatal testosterone levels do not affect later empathy.

We would challenge both these conclusions, on two grounds. First, Nadlers study only included men, whereas van Honks study only included women. So while we agree that administering extra testosterone to men does not appear to reduce their empathy, Nadlers study cannot be regarded as an attempt at replicating the van Honk study. A large-scale study of women would be needed for that.

And perhaps giving women extra testosterone does reduce their empathy (as van Honk found) while giving men extra testosterone does not. This could be because women on average score higher on the eyes test than men do, so there is more room for their scores to decrease. Also, on average, women have lower circulating testosterone levels than men, so large changes in their testosterone levels may have bigger effects on empathy.

In Nadlers study, the testosterone levels of male participants were elevated two or threefold. In contrast, in the van Honk study, the testosterone levels of female participants were elevated at least tenfold. It is possible, then, that a higher dose of testosterone would have affected empathy in men.

Second, digit ratio may not be a good proxy of how much testosterone someone was exposed to in the womb, as other factors may affect this ratio. To properly study prenatal testosterone, it should be measured directly, using prenatal samples.

Of course, measuring prenatal hormone levels in the womb is very difficult, but it is essential because testosterone exerts many of its programming effects during a critical time window when the brain is developing.

That is why we measured prenatal testosterone levels in the amniotic fluid surrounding the developing fetus in women who opted to have an amniocentesis during pregnancy and then following up the child years later to see how they developed. We confirmed that the higher the level of prenatal testosterone, the lower their scores on the eyes test of empathy when tested at age 6 to 8 years.

In their press release, Nadler and colleagues argue that their new data challenges the extreme male brain (EMB) theory of autism. But Nadlers study has little to do with the EMB theory.

The EMB theory makes no predictions about what will happen to a persons empathy if you give them more testosterone. The EMB theory simply states that, on tests of empathy, typical females will on average score higher than typical males, and autistic people will on average score lower than typical males.

The EMB theory also states that on tests of systemizing the drive to analyze or construct systems in terms of rules typical males will on average score higher than typical females, and that autistic people will on average score higher than typical males.

The EMB theory was recently confirmed in the largest test of sex differences in empathy and systemising among 600,000 people, and in the largest study of autism, among 36,000 autistic people.

And in other recent studies, we showed that several prenatal sex steroid hormones, such as testosterone and oestrogen, are elevated in the amniotic fluid of autistic boys, demonstrating the importance of prenatal sex steroid hormones in changing brain development.

So, while the Nadler study is impressive for its scale, we now need a direct replication study of testosterone effects on womens cognitive empathy. Finally, it is important to separately study the effects of testosterone on the prenatal brain, compared to the effects of the same hormone on the adult brain.

This article was originally published on The Conversation by Simon Baron Cohen, Alexandros Tsompanidis, Richard Bethlehem, and Tanya Procyshyn. Read the original article here.

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Why Scientists Disagree on Testosterone's Link to Empathy - Inverse

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Sep 18th, 2019 | Filed under Testosterone

Though many are magical, some of the human body's functions (and dysfunctions) can be disgusting, frustrating and downright weird. So it's no surprise that discussing some of its more sensitive operations can be embarrassing. And while this may cause anyone to be reluctant to talk about their health concerns, it seems men, in specific, are most hesitant about it.

Vancouver-based health writer and physician Melissa Lem sees this clearly as a family doctor usually the first person to field our body-related questions. "An informal survey of my own patients over the past week showed that I saw almost twice as many women as men," she says. That finding is consistent with Canadian research suggesting women visit the doctor more often, and research conducted by the American Academy of Family Physicians that suggests men are less likely to get their recommended routine screenings. Dr. Lem says she often hears comments like, "I didn't want to come in today, but my wife/girlfriend told me to," along with "doorknob questions" the most sensitive questions men save and ask when they're just about to leave the exam room.

As to why this is, Dr. Lem believes it's a combination of socialization and habit. "Men are frequently taught from a young age that complaining is a sign of weakness. Studies show that men who hold more traditional views of masculinity are more likely to avoid doctors and minimize their symptoms," she says. "Interestingly, research also shows that men tend to be more honest about their health with female doctors." Dr. Lem also notes that since women are more likely to visit the doctor from a young age to address birth control and begin routine screenings, such as Pap tests, it's usually a habit they form earlier.

Of course, avoiding addressing health concerns can have grave consequences. "Canadian men tend to have higher rates of chronic health conditions, such as diabetes, heart disease and cancer," says Dr. Lem. "Not only that, they die an average of four years earlier than women." When men do visit the doctor, she says that they are often most reluctant to discuss "issues that involve sensitive parts of the body, their sexual health and mood."

With all of this in mind, we reached out to family doctor and sexual health expert Manisha Sharma of Ontario's Oakwood Health Network, which specializes in treating erectile dysfunction. We asked her some of your most delicate questions consider it a primer before you finally reach out to your own GP.

Why is my penis curved?

No matter which way it points, a curve is common. The condition is called Peyronie's disease, says Dr. Sharma, and it affects about 10 per cent of the male population. "It's typically caused by scar tissue that has formed on one side of the penis," she says. "Usually the curve isn't painful and doesn't interfere with sex, but in some cases it can." Fortunately, Peyronie's disease is treatable. A urologist or specialized clinic may treat it with medication, surgery or shockwave therapy.

One of my testicles is bigger or hangs lower than the other; is this normal?

It may feel weird, but "it's totally normal," Dr. Sharma says. She adds that if you're concerned about a difference in size, you can ask your family doctor to take a look. (Fun fact: In terms of the way they hang, it may be an evolutionary feature. Fluctuating "scrotum hang" allows for temperature regulation finicky sperm is produced and stored more effectively away from body heat, yet doesn't like to be too cold plus the system is structured in a way that lets each testicle migrate independently to keep things optimal.)

Why am I urinating more frequently?

A change in how often or how much you're urinating can be a symptom of a variety of issues, including a urinary tract infection (which is often also painful), prostate issues or a weakened pelvic floor, says Dr. Sharma. The pelvic floor is a muscle that supports your internal organs and "it plays a big role in urinating, defecating, erections and orgasms," so it's important to keep it healthy and strong. "Talk to your family doctor about changes in your typical urinary patterns," she says, to get to the root of the problem.

Do I have low testosterone? Do I need higher testosterone?

"Testosterone levels fall as men age," Dr. Sharma notes. However, if you have lower than normal levels, such a deficiency can bring along a host of symptoms, such as tiredness, erectile dysfunction and loss of muscle mass. If you suspect lower-than-normal testosterone levels, Dr. Sharma says that your doctor can order a simple blood test to see if your level falls within the normal range and, if you're low, suggest the best form of treatment.

Can supplements raise my testosterone level?

No, supplements will not raise your testosterone level. However, if you want to naturally support your testosterone levels, Dr. Sharma suggests keeping off excess weight and exercising regularly.

Is erectile dysfunction (ED) caused by low testosterone?

Assuming that low testosterone negatively affects a man's erectile capabilities may seem logical, but it isn't always the case. "Not all men who have ED have low testosterone," says Dr. Sharma, "and not all men with low testosterone have ED." There are a host of factors that contribute to ED, she explains. Since blood flow plays a significant role in erections, anything that interferes with blood flow to the penis, such as age, smoking, excess weight, certain prescription medications and health conditions like diabetes and low testosterone, can impair erection.

What can I do about ED?

"When treating ED, it's important to have a variety of strategies available," says Dr. Sharma, and this might include taking prescription pills (though "they don't work forever, some men can't take them and they have side effects"). Lifestyle changes such as improving fitness and nutrition, strengthening the pelvic floor and seeking therapy for unresolved anxiety or trauma (since ED can be mental healthrelated) are other potential strategies. Shockwave therapy and penile pumps can also serve to aid the issue, she says. Talk to your doctor to determine the appropriate course of action.

Does having ED mean I'm sterile?

The erectile system is separate from sperm production and quality, so having ED doesn't necessarily mean you're sterile. However, the issues can go hand in hand. "Men who experience fertility issues can also have ED," says Dr. Sharma. "If you suspect a fertility issue, your doctor can refer you for testing."

I don't have ED, but I do have a low sex drive. Why?

Sex drive, like the ability to achieve an erection, can be affected by a variety of factors, such as age, low testosterone and certain prescription medication, Dr. Sharma explains. "However, if you can get good erections but have no desire to have sex, you could [also] be dealing with a mental health issue." Stress can be an obstruction to sexual enjoyment and/or desire, she says, as can depression. Seeing a mental health professional, either alone or with your partner, can help pinpoint, treat and manage these issues.

How can I stop premature ejaculation? Are there things I can do at home?

Managing stress and professionally treating larger issues such as depression and anxiety is key, says Dr. Sharma, as these things are all believed to be contributing factors to premature ejaculation. "If you have ED, treat it," she adds. "Men with ED tend to climax sooner as they fear the loss of the erection." If possible, Dr. Sharma suggests masturbating one to two hours before sexual activity, and keeping the pelvic floor strong through physiotherapy. The pause-squeeze technique might also be helpful: when the urge to ejaculate occurs, have your partner squeeze where the head of your penis meets the shaft until the sensation passes (this may take several seconds) and repeat as needed.

What does my prostate do, and how do I know if there's an issue with it?

The prostate gland is a male reproductive organ that aids in the production of semen. "It's below the bladder, [in front] of the rectum and it goes around the tube that carries urine and semen out of the body," says Dr. Sharma. Because of its location, when the prostate becomes enlarged, it can constrict the urethra and obstruct urine flow. "Discuss with your doctor if you have difficulty completely emptying your bladder, a weak, dribbling urine stream or [are] urinating frequently at night," she advises.

At what age will my sex drive decrease, and what can I do about it?

Sex drive tends to decrease as we age, however, Dr. Sharma notes that men can retain and prolong their sexual drive well into their 60s, 70s and beyond. She highlights losing weight and exercising (giving you more energy), diagnosing and treating low testosterone, and reducing stress or anxiety as keys to preserving and increasing your sex drive.

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Men, we've got answers to the health questions you may be too afraid to ask - CBC.ca

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Sep 18th, 2019 | Filed under Testosterone

Nevertheless, Sacramento-born-and-raised baritone Lucas, who decided to keep singing with her booming, low-voice type after her physical transition rather than trying to retrain her voice to sing soprano or mezzo roles, is rising to the very top of her profession.

In May, she became the first trans singer to perform a lead role in a classic operatic work in the U.S. when she starred in "Don Giovanni" with the Tulsa Opera in Oklahoma.

In October, she will play a lead role with the English National Opera in London.

Yet Lucas said she often dons fake facial hair and standard menswear for auditions to prove she can play roles that normally go to cisgender male performers.

"A lot of people are really confused because they have 'Ms. Lucia Lucas' on their paperwork as a baritone," Lucas said. "But I'm presenting with a beard in masculine attire."

When it comes to perceptions around gender transition, most people tend to focus on external physical changes.

But taking the male hormone testosterone doesn't only tend to increase body hair and muscle mass. It also lowers the voice.

"Testosterone thickens the vocal folds," said UCSF voice speech pathologist Sarah Schneider, who specializes in working with transgender singers.

But learning a new lower-pitched way of speaking and singing often comes with enormous challenges.

"Some people describe it as feeling locked in," Schneider said. "They're not quite sure how to navigate the lower voice."

Schneider said surgery for lowering vocal pitch exists. But few people go that route, because of the lowering effect of testosterone.

Its a completely different story for people taking estrogen.

"For trans females, taking female hormones does not actually change the voice," Schneider said.

She said surgery on the vocal folds is a possibility for people who want to sing higher. But its a major risk.

"The outcomes are not always predictable," she said. "And we don't know if it's going to impact that accessibility to the upper range."

It's possible to develop a higher speaking and singing register with careful training and consistent practice.

Schneider said the best way to keep the voice healthy through the gender reassignment process is to keep using it without pushing too hard.

"It's just a matter of looking at it like training," she said. "We work on these different muscle patterns so they feel accessible."

Opera's diversity and inclusivity challenge extends well beyond transgender singers. As an African American, Bay Area soprano Breanna Sinclair is especially troubled by this reality.

"In the classical world, there are still other issues that we have to deal with first before we get to the transes, because there is a history of racial discrimination," said Sinclair,who abandoned the tenor range she was mostly forced to sing in while growing up, and has focused on extending her voice upward as a soprano. "Its not a diverse genre of music. And I don't see many African Americans or many Asian or Latino women playing lead roles."

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Three Transgender Opera Singers on the Risks They Took to Live Authentically - KQED

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Sep 18th, 2019 | Filed under Testosterone

Not too long ago, a paper published in the journal Current Biologyidentified a unique somatic mutation that essentially widens the gap between our chronological and epigenetic age. Our chronological age refers to the number of years weve been alive, while our epigenetic age is a molecular assessment of the state of our biology. While this biological count doesnt encompass every aspect of aging, its the most accurate risk predictor for most age-related diseases.

Its not only possible for your epigenetic clock to surpass the number on your birthday cake, but some researchers believe the biochemical test might be the key to reversing the aging process. According to a new study published in the journalAging Cell, after being administered a three-drug combo, participants successfully restored their thymus gland, thus reversing some important health factors associated with aging. From the report: Using a protocol intended to regenerate the thymus, we observed protective immunological changes, improved risk indices for many agerelated diseases, and a mean epigenetic age approximately one and a half years less than baseline after one year of treatment.

The thymus gland, located behind the sternum, is only active until were done with puberty, protecting us from diseases by producing important white blood cells. Once puberty is complete, the gland begins to slowly shrink over the course of our lifetime, getting clogged up with fat withal.

Employing a crop of otherwise healthy young men, the researchers behind the latest study derived their conclusion from three different drugs: Recombinant human growth hormone (rhGH), which has been previously studied in anti-aging research,Dehydroepiandrosterone (DHEA) and metformin. The last two were primary to mitigate the diabetes risk increase associated with rhGH, but neither have any effect on the thymus directly.

While none of them experienced any health setback from the regimen, 77% of the participants evidenced reverse aging in their thymus. More dramatically, after nine months of adhering to the three-drug regimen, the participants involved in the study were epigenetically two and a half years younger. The authors of the study wrote, PSA, percent free PSA, and the ratio of PSA to percent free PSA, an overall index of prostate cancer risk, improved significantly by day 15 of treatment and remained favorably altered to the end of 12months. A brief spike in PSA at six months in two volunteers was rapidly reversed and, after volunteer consultation, was interpreted as reflecting sexual activity close to the time of PSA testing. No change in testosterone levels was observed.

These results certainly suggest a bright future for epigenetic research down the pike, but the study had limitations, including the small size of the participant group. The authors intend to further their research in the very near future.

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Researchers may be 1 step closer to reversing the aging process - Ladders

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Sep 18th, 2019 | Filed under Testosterone

As we age, our bodies experience a number of changes which affect our overall quality of life. These changes, though natural, can lower the level of satisfaction we feel and compromise our physical well being. Much of how we feel both physically and emotionally results from a hormonal balance, which if off, can result in many unpleasant physiological changes. Hormones play a pivotal role in regulating our emotions and physical health. As men and women age, a decrease in specific hormones can result in negative symptoms and a decrease in general life satisfaction.

Even before a woman enters menopause, she may experience a significant decrease in the hormones estrogen, progesterone, and testosterone. The decrease in these hormones compromises both physical and mental health. Although typically associated with men, testosterone is an important hormone in the overall regulation of female health, as well. Testosterone naturally decreases with age and can result in a myriad of unpleasant health issues for women. Symptoms of low testosterone can include sluggishness, muscle weakness, fatigue, restlessness, decreased libido, weight gain, reproductive issues, and decreased bone density. These symptoms are more than a nuisance and can significantly lower the quality of life for women as they age.

Fortunately, there are options available for women to increase testosterone and counter the negative effects resulting from a lack of this hormone. Bioidentical hormone replacement therapy is an option for women experiencing decreases in not only estrogen and progesterone but also testosterone. The symptoms associated with a hormonal imbalance no longer have to be considered as a natural effect of aging. Hormone replacement therapy can help correct the imbalance and reverse the effects of decreased testosterone.

Bioidentical hormone replacement therapy works by righting the levels that have decreased with age, and these hormones are bioidentical, or the same as, the hormones a female body naturally produces. Introduction of these hormones is administered in typically three ways including topical creams, pills, and pellets. Topical creams are carefully formulated by dose and are rubbed into the skin, subsequently entering the bloodstream. Pills are similar to birth control pills taken orally, but the dosage needs to be carefully determined as much of the hormone is broken down by the liver. Pellets, typically administered for testosterone, are placed in the hip and deliver a constant stream of the hormone over several months.

The administration of BHRT must be monitored by medical professionals to ensure the correct dosage and administration of the hormones. In discussions with your doctor, you can determine the most comfortable method of hormone administration. As your body has naturally begun to decrease hormone levels, BHRT will need to be maintained consistently to ensure that hormone levels remain constant and effective. Many women begin to notice significant positive changes approximately two weeks after beginning BHRT. Regular consultations with medical professionals will ensure that you are receiving the most benefit from hormone replacement therapy.

Premenopausal women, women going through menopause, and women who have experienced ovary, adrenal, or pituitary gland dysfunction can all experience low hormone levels. Decreased hormone levels can result in a host of unpleasant physical and mental symptoms that can be reversed through the administration of bioidentical hormone replacement therapy. A consultation with your doctor will determine if you are a good candidate for BHRT. You do not have to endure these side effects of aging. Through BHRT, you can reverse the decreased levels of hormones and regain the vitality in your life.

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What's Causing My Low Testosterone? - Pulse Headlines

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Sep 18th, 2019 | Filed under Testosterone

Anabolic and Androgenic steroids, most of which are banned in sports, were seized at Chennai airport on Sunday, according to a press release.

Rajan Misra, who had come from Kolkata, was detained on suspicion and later taken in for questioning by officials, the release said. When officials checked the baggage, they found he had concealed these anabolic and androgenic steroids: D-Bolin (metandienone) 900 pieces, Stanoline (stanazolol) 396 pieces, Finabolone A (trenbolone acetate) 340 pieces, Finabolone E (T.enanthate) 90 pieces, Testolone E (testosterone enanthate) 500 pieces, Equibolone (boldenone undecylenate) 400 pieces, parboline E100 (trenbolone enanthate in 100 pieces, Parabolin Hex 100 (trenbolone hexahydro benzylcarbonate injection) 100 pieces, Masterlone (drostalonone propionate) 300 pieces, Primobolone (metheno enanthate) 200 pieces, Testolone C (testosterone cypionate) 30 pieces, and T. Entboline (testosterone enantate injection) 100 pieces, the release said. These drugs are worth 10 lakh.

Misra told the Customs officials that he got these from Cambodia to supply to local gyms in Kolkata, and that he would usually go to Lucknow and now, for the first time, he came to Chennai. These drugs were used by body builders and sometimes encouraged by gym owners, the release said.

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Steroids worth 10 lakh seized at Chennai airport - The Hindu

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Sep 18th, 2019 | Filed under Testosterone