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Stocks to Watch: 3 Companies Working on Next-Gen Weight Loss Drugs – InvestorPlace

Jan 28th, 2024
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These weight-loss drug stocks have tremendous potential

Everyone knows that America has a major obesity problem. Because of this, new anti-obesity drugs are going to generate a great deal of revenue and profits their companies. What people dont realize is that those weight-loss drugs come with high valuations and equities that reflect most of the profits they will generate. Consequently, investing in firms with lower valuations that are focused on improving or developing superior weight-loss treatments is a better way to go. Here are three weight-loss drug stocks that are in the latter category.

Source: shutterstock.com/Champhei

The popular weight-loss treatments, known as GLP-1 drugs, have an important, very negative side effect: they strip away muscle in addition to fat, Investors Business Daily explained. Thats a major reason why people who take the drugs find it difficult to keep the weight off once they stop taking the medicine. Also noteworthy is that, because of the muscle loss, these drugs tend to come with higher mortality rate.

Biohaven Therapeutics (NYSE:BHVN) is developing a drug that blocks myostatin in order to reduce fat while building up lean tissue, which includes muscle. Myostatyin is a protein that prevents muscle growth. In studies of animals, BHVNs drug increased lean tissue and promoted weight loss.

Meanwhile, the drug, known as Taldefgrobep alfa, is undergoing Phase 3 testing for use as a treatment for an unusual disease calledspinal muscular atrophy.

Whats more, Taldefgrobep alfa, can conceivably be approved in the medium term as a treatment for spinal muscular atrophy and then be prescribed off label by doctors as a treatment for obesity. In that case, BHVN stock would soar tremendously, and the company could become a takeover target. The companys huge potential makes BHVN one of the best weight-loss drug stocks.

Source: Shutterstock / PopTika

In a Phase 2 study, a 2.4 milligram dose of Altimmunes (NASDAQ:ALT) GLP 1 drug, pemvidutide, lowered participants weight by an average of 15.6% 13.4 percentage points more than those taking a placebo. That compares very favorably with the results of a study of Eli Lillys (NYSE:LLY) popular GLP-1 drug, in which those taking the medicine lost an average of 7.1% more weight than those taking a placebo.

Also noteworthy is that pemvidutides tolerability was reportedly better than that of other GLP 1 treatments. Finally, the drugs reduced LDL cholesterol more than two other popular GLP 1 drugs, semaglutide and tirzepatide.

Given these points, the $538 million market capitalization of ALT stock far undervalues the shares, while the company could easily become a takeover target.

Source: Michael Vi / Shutterstock.com

Canadian bank BMO Capital is bullish on Amgens (NASDAQ:AMGN) two anti-obesity drugs, AMG 133 and AMG 786. The bank thinks that the drug maker could report upbeat data on the treatments later this year.

Moreover, AMG 786 is an oral drug, giving it an important advantage over most of the other GLP 1 drugs which are injected.

Additionally, AMG-133 may only have to be taken once a month, unlike its competitors on the market which have to be taken daily or weekly.

On the date of publication, Larry Ramer did not hold (either directly or indirectly) any positions in the securities mentioned in this article. The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines.

Larry Ramer has conducted research and written articles on U.S. stocks for 15 years. He has been employed by The Fly and Israels largest business newspaper, Globes. Larry began writing columns for InvestorPlace in 2015. Among his highly successful, contrarian picks have been SMCI, INTC, and MGM. You can reach him on Stocktwits at @larryramer.

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Study shows lasting benefits of weight loss and diabetes remission for the heart and kidneys – News-Medical.Net

Jan 28th, 2024
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Researchers in the School of Population Health atRCSI University of Medicine and Health Sciences have providednew evidence of the health benefits of weight loss efforts that lead to diabetes remission fortype 2diabetespatients.

For participants in the weight-loss trial who were able to achieve remission i.e. reduce the need for medications and reduce their HbA1c levels(a measure of blood sugar control), the research found there was a 40% lower rate of cardiovascular disease and 33% lower rate of chronic kidney diseasein this group.

While previoustrials have shown that substantial weight loss using diet and lifestyle can reverse type 2 diabetes, the new researchpublished in Diabetologiais among the first to show that reversal of diabetes, in turn, affects cardiovascular and kidney disease outcomes.The researchwas ledby Professor Edward Gregg, Head of the RCSI School of Population Health.

The studycalled Look AHEAD(Action for Health in Diabetes)monitoredover 5,000 patients duringa period of 12 years.The magnitudeof risk reduction was greatest for participants with evidence of at least fouryears of remission.

Using lessons learned from this study we can help inform diabetes treatment methods andimprovequality of life for people with type 2 diabetes.It has highlighted the significance of weight loss for achieving remission from type 2 diabetes and then long-term positivecardiovascularand kidney disease outcomes

Professor Edward Gregg, Head of the RCSI School of Population Health

Over the course of the study, the effect of intensive lifestyle intervention was compared with that of diabetes support and education on cardiovascular diseaseand other long-term health conditions.It wasnoted that although 18% of participants achieved remission at some point during follow-up, the percentage of participants withcurrentremission had decreased to 3% by the 8th year of the study, underlining the challenges of keeping weight off using lifestyle interventions.

RCSI researchers collaborated on the study with colleagues Wake Forest University, Brown Universityand other study sites in the United States.

Source:

Journal reference:

Gregg, E.W., et al. (2024) Impact of remission from type 2 diabetes on long-term health outcomes: findings from the Look AHEAD study. Diabetologia. doi.org/10.1007/s00125-023-06048-6.

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Our sense of taste helps pace our eating understanding how may lead to new avenues for weight loss – The Conversation

Jan 28th, 2024
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As a scientist who investigates hunger and weight control, Im interested in the way our brains let us know weve had enough.

As we begin to feel full, we slow down how quickly we eat. For decades, scientists have thought that this change in pace was driven solely by signals from the stomach and intestines to the brain. But a new study from my lab at UC San Francisco shows that, in fact, there is another process at work, and it begins as soon as we taste our food.

This process has remained unknown until now because we havent been able to observe the relevant brain activity in an animal while it was eating. The neurons involved are deep in the brainstem. A graduate student in my lab, Truong Ly, developed new techniques that allowed us to see the activity of these neurons for the first time, in mice.

We discovered that there are two parallel pathways that control our eating one that restrains how fast you eat and another that limits how much. The taste of food activates the first pathway. This may seem counterintuitive: We usually want to eat more of food that tastes good. But although we may not be consciously aware of it, the sensation of taste also paces our eating.

This first pathway, as scientists have long thought, involves signals from the gut, but our study shows that those cues may also be overridden when the brain receives signals from taste receptors in the mouth, saying Theres food here. Were working on figuring out how this sensory filtering works, in an effort to uncover new strategies for treating obesity.

Neurons involved in the second pathway we studied, the one responsible for limiting how much you eat, do so by releasing the hormone GLP-1, which creates a long-lasting feeling of being full. New drugs for obesity, such as Ozempic and Mounjaro, mimic the activity of GLP-1. My team is now trying to understand how this enduring satiety works, to gain a deeper understanding of these new drugs and possibly identify new avenues for controlling weight.

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Intermittent Fasting Does Work For Weight Loss But Only if You Follow This Rule – ScienceAlert

Jan 28th, 2024
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Intermittent fasting is an increasingly popular way to attempt to lose weight by forgoing meals. A new review concludes diet restriction might not be enough to shed some body fat, at least not on its own.

Researchers from the University of Southern Denmark, and Wageningen University in the Netherlands, have summarized the existing knowledge we have about the practice of fasting.

A lot of data has been collected over the years, covering multiple aspects of the way that intermittent fasting affects the body. One of the key takeaways is that intermittent fasting has to be combined with managing the intake of calories in order for any weight loss to be seen. It's the reduction in total calories that makes the difference, rather than long breaks between meals.

"When you do intermittent fasting, the fundamental rule still applies that we should consume fewer calories than we burn, if we want to lose weight," says molecular biologist Philip Ruppert from the University of Southern Denmark.

"This means that intermittent fasting does not give you a free pass for eating unlimited quantities of food. It's basic physiology, and fasting can't change that."

There's a lot of ground covered in the review, looking at the effects that intermittent fasting has at the molecular level. These include the release of the breakdown of the body's store of fatty acids to provide energy, and ketogenesis (when high rates of this fatty acid breakdown leads to the liver producing ketones).

The paper also touches on the feelings of euphoria that some people get after several days of fasting, as feelings of elation start to replace feelings of hunger perhaps in response to the changing chemical processes going on in the body and the brain.

This is something Ruppert himself has experienced while fasting. For now, scientists aren't sure why this happens, but one possibility is that ketones are supplying energy more efficiently to the brain, so it hums along in a happier state.

"The brain is fed with ketones during fasting," says Ruppert. "Maybe that's why you may experience this clarity."

There are various different approaches to intermittent fasting, with some people not eating for certain hours in the day, and others not eating during certain days in the week. Plenty of well-known public figures have signed up for these diets too.

And the research team points to numerous health benefits of fasting beyond weight loss that have been recorded, including lower blood pressure. What's clear though is that everyone is different in their response to fasting, and it's important to consult with a doctor if you're thinking about lowering your food intake.

"There are indeed many health benefits to intermittent fasting, but fasting itself does not lead to significant weight loss," says Ruppert.

The research has been published in Trends in Endocrinology and Metabolism.

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The #1 High-Fiber Snack to Buy at Target for Weight Loss, According to a Dietitian – EatingWell

Jan 28th, 2024
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Target is a fun place to shop. You can hit up their Dollar Spot or browse the cute clothes, soft blankets, beautiful home decorand find your new favorite snack, all in one trip.

If your goal is to lose weight, increasing your fiber intake is a smart move. Fiber has a long list of health benefits, including reducing the risk of heart disease, type 2 diabetes and some cancers, but chances are you arent getting enough, according to the USDAs Economic Research Service. Americans eat about 16 grams of fiber per day on average, much less than the recommended 28 grams for a 2,000-calorie diet.

Fiber comes from plant foods; the two main types are soluble and insoluble fiber. Soluble fiber slows down digestion, and insoluble fiber bulks up your stool and reduces constipation. Both types are found in fruits, veggies, nuts and grains, and both have health benefits.

Along with disease prevention, dietary fiber promotes weight loss. Fiber swells up in the stomach, which increases satiety, explains Kelli Davenport, M.S., RD, a registered dietitian with Top Nutrition Coaching. Given that fiber will also cause food to move more slowly out of the stomach, youll feel fuller for longer. In addition, soluble fiber has been shown to help decrease appetite, she adds. (A 2019 systematic review and meta-analysis in Foods backs up these hunger-regulating benefits of soluble fiber.)

Whats more, fiber-packed foodswhole grains, fruits, legumes and nonstarchy vegetablestend to be lower-calorie options. Filling your diet with these types of foods can also support weight loss, adds Natalie Carroll, RDN, a registered dietitian nutritionist who is also with Top Nutrition Coaching.

So what is the best weight-loss snack to get at Target if youre ready to focus on fiber? Read on to find out which one our dietitians picked.

A high-fiber snack should contain at least 3 grams of fiber per serving. The best high-fiber snack would consist of whole foods, such as nuts, fruit, edamame, veggies or air-popped popcorn, says Davenport. Packaged snacks may be an option, too, but look for minimal ingredients, says Carroll. Foods like baked green pea snacks, whole-grain crackers, hummus and bean dips are all great options.

Too much added sugar can cause blood sugar spikes and dipsa roller coaster your body doesnt want to be on. You might feel jittery or restless when experiencing a blood sugar spike, says Davenport. But if you have diabetes, this spike can cause blurred vision, fatigue, dry mouth, increased thirst or headache, she says. A resulting crash doesnt feel much better, either, potentially producing shakiness, sweating, fatigue, irritability, dizziness and reduced concentration. Be wary of added sugars, Davenport says.

Fiber promotes satietyand so does protein. Consuming a high-protein diet along with regular exercise was found to decrease body and visceral fat and improve blood lipids, insulin sensitivity and inflammation compared to a control group, according to a 2021 study in the journal Frontiers in Cardiovascular Medicine on middle-aged adults with obesity. When picking a snack, think fiber and protein.

Target has a lot of healthy snack options, but when it comes to a high-fiber weight-loss snack, theres one that wows our dietitians. Carroll recommends Seapoint Farms Dry Roasted Edamame Sea Salt. This delicious and crunchy snack is packed with 8 grams of fiber per cup and also provides plant-based protein, she says. Edamame also provides appetite-regulating soluble fiber.

Whats more, the ingredients list is simple: soybeans and salt. And it pairs well with a variety of other foods. I love how versatile this snack is, Carroll says, suggesting eating this edamame on its own, mixed into a homemade trail mix with nuts and dried fruit or added to air-popped popcorn.

Along with being high in weight-loss-friendly fiber, dry-roasted edamame also comes with additional health benefits.

Theres just something about soy: A 2019 review published in the journal Nutrients looked at over 22 studies. Researchers found that women who ate soy products regularly had lower body weights, BMI, waist circumference and body fat percentages. Soys fiber, protein and compounds called isoflavones may help promote a healthy weight.

Soy contains phytoestrogens, which have a similar chemical structure to estrogen, the female sex hormone. That may be why a 2022 review published in the journal In Vivo found that pre- and post-menopausal women who ate more soy products had lower rates of breast cancer. Study authors said that soy can imitate estrogen in the body, which can reduce the risk of breast cancer.

Stay sharp with soy: A 2020 review published in Nutrition Reviews looked at the results of 16 randomized controlled trials that tested the effects of soy isoflavones on brainpower. The authors found that participants who ate more soy products had better memory and cognitive function as they got older.

If your goal is to lose weight, you have a lot of great high-fiber snack options. But the one that comes out on top is Seapoint Farms Dry Roasted Edamame, available at Target. With protein and fiber, dry-roasted edamame is a pleasingly crunchy snack that offers protein and fiber to keep you full and satisfied until your next meal.

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All About Jazz Jennings’ 70 Lb. Weight Loss Journey – Women’s Health

Jan 28th, 2024
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Famous YouTuber and activist

Jazz shared the news with an Instagram post that featured a picture of her posing on the beach in a bathing suit.

Feeling happier and healthier than Ive been in years, she wrote in the caption. I still have a ways to go, but Im so proud to finally be taking the necessary steps toward bettering my mind, body, and spirit.

Jazz first started talking about wanting to start her health and weight loss journey back in 2021. So, what has helped Jazz reach her health and wellness goals? Heres everything to know so far.

In June 2021, Jazz posted two side-by-side photos of herself on Instagram, showing a before and after weight gain comparison, with a caption that explained where she was feeling mentally at that point.

Im posting this photo because its time for me to address my weight gain and hold myself accountable, she wrote. Im ready to change my ways; Ive been saying Im ready to turn over a new leaf, but Im running out of trees now. Im ready to take the initiative and create positive changes when it comes to my health and body.

She ended on this note: Love you all, and thanks for understanding the battle Im fighting to win.

Jazz has binge-eating disorder, something she also addressed in her 2021 post.

As many of you have noticed, over the past few years, I have gained a substantial amount of weight, she wrote. I suffer from binge-eating disorder, a disease in which Im not only addicted to food, but I eat it in large quantities.

Jazz also said that bingeing, along with an increased appetite she experiences from some of the medications she takes, caused her to gain almost 100 pounds in less than two years.

While Jazz hasn't shared her exact diet and fitness routine in the intervening years, she has shared several Instagram posts demonstrating some of the steps shes taken to maintain a healthy lifestyle, which includes working out and playing lots of sports.

In January of 2024, she shared a video of herself running with her dad, who is a total hype man. There she is.the 2024 Jazz, he cheered as they ran together.

Jazz has also shared photos of herself posing next to a tennis court, writing, one step at a time, in the caption.

Oh, and the star even joined a club lacrosse team at Harvard, where she goes to college. Had my first lacrosse game with the Harvard club. It was so much fun! she captioned a photo of herself on the field.

In 2022, Jazz shared a video of herself doing boot camp workouts with her brother, Sander. In the clip, Jazz and Sander do jumping jacks, planks, wall sits, and a half mile run. She wrapped things up by carrying Sander on her back.

It's not clear how often they did these "boot camps," but they definitely seemed like they were working hard while also having fun together.

Jazz said in her latest post that shes lost 70 pounds, and plans to lose more.

Korin Miller is a freelance writer specializing in general wellness, sexual health and relationships, and lifestyle trends, with work appearing in Mens Health, Womens Health, Self, Glamour, and more. She has a masters degree from American University, lives by the beach, and hopes to own a teacup pig and taco truck one day.

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Oprah Winfrey Says Shes Almost At Her Goal Weight After Working So Damn Hard And Taking Weight Loss Drugs – SheFinds

Jan 28th, 2024
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Skip the Gym and Use These 7 Easy Tips to Lose Body Fat at Home – CNET

Jan 28th, 2024
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There are several reasons to work out, from focusing on your fitness to getting better sleep to improving your mental health. Reducing body fat is another thing many people are trying to achieve with exercise.

Despite what you may have heard, you can't target a specific area for fat loss. Many studies have disproven spot-reduction techniques, such as abdominal exercises or upper-body resistance training. Fat cells from all over the body can be broken down when we exercise; they don't break down in one specific area.

The good news is that exercise and diet may lead to a whole-body trimmed physique -- and only 15 minutes of exercise daily can benefit you greatly.

Below are some of the best ways to lose fat right in the comfort of your own home.

Walking is an ideal workout to do outside the gym. It can be done around the neighborhood or at a park. On good weather days, you can also get some much-needed fresh air. Plus, it's free and you can take your dog with you, if you have one -- pets need exercise, too!

Walking is also a body fat buster. One study found that healthy postmenopausal women lost 3.9% of body fat after 30 weeks of walking and 1.8% after 15 weeks of walking. While we can't target specific areas, walking can help lose belly fat.

According to Nature, 30 minutes of walking most days of the week showed a significant reduction in body weight and body fat percentage. The study even found that 30 minutes of walking may be as beneficial as 60 minutes (with a healthy diet).

One diet trend that has risen in popularity over the years is intermittent fasting. As the name suggests, this is where people fast for a certain time, and then eat at other scheduled times. One study review found that subjects who fasted intermittently had weight loss ranging from 0.8% to 13%. The idea is to force the body to use up its immediately accessible sugar stores and start burning fat.

A perk of intermittent fasting is that you can customize it to your preference and ability to abstain from food. According to John Hopkins Medicine, fasting can last for a certain number of hours every day or even just eating one meal per day for two days out of the week. For instance, you might only eat during an eight-hour period each day and fast the rest of the day.

It's important to note that intermittent fasting is not for everyone, especially those at risk for disordered eating or during pregnancy. Before trying intermittent fasting, consult with your doctor to ensure you follow the best plan for you and your goals.

This point might seem counterintuitive since we just covered how you can't burn fat in one specific region, no matter how many stomach crunches you do. But you can balance weight training to target multiple muscle groups or work on certain body parts as part of a whole-body workout. That may give you more balance and a lean appearance and help with body composition.

If you don't have dumbbells at home, check out these household items that double as weights.

Weight training can also help lose fat while building muscle. Studies show that 3 pounds of lean muscle weight gain corresponded to 4 pounds of fat weight loss. Resistance training has also been shown to reduce body fat percentage, body fat mass and visceral fat (the fat that surrounds your organs).

Resistance training, be it with weights or bodyweight exercises like pushups, is recommended by the USCenter for Disease Control and Prevention for at least two days a week, so it can be a fairly easy exercise to fit into your schedule.

Another great exercise idea to lose body fat is to start running or jogging. Like walking, you can do it around the neighborhood or in a park, so it's free. If you are concerned about the weather, you can also find an indoor track at a gym or community center. You can also consider getting a treadmill to run or jog at home.

Sprint training is especially good at busting the fat, where you switch how fast you run every several seconds. The CDC also recommends 150 minutes of moderate-intensity aerobic activity, 75 minutes of vigorous-intensity activity or a mix of the two every week. The CDC lists walking at a rate of a 15-minute mile as moderate activity and jogging or running as vigorous.

This type of exercise, often shortened to HIIT, is where you exercise as hard as you can for short bursts and then spend some time doing lower-intensity training. A perk with this exercise is that it can be any activity that gets your heart pounding, from jumping jacks to stair climbing, so it's customizable based on how much room you have and what equipment you have around.

It's a fat buster, too. It may result in a modest reduction of overall and abdominal fat.

You can do 30 seconds to several minutes of hard-as-you-can working out and then one to five minutes of recovering with a lower-intensity exercise level. These workouts typically go for about 30 minutes, including five-minute warm-ups and cool-downs, but can be tailored to suit comfort and fitness levels. Typically, the aim is to do these sessions five times a week.

You can also focus on your diet. While there are no foods that'll magically burn your fat, there are foods that can increase your metabolism. Most of these foods are high in protein and good-for-you fats, making you feel fuller longer.

Some foods to incorporate into your diet if you're trying to reduce fat, as listed by the CDC, Healthline and the World Health Organization, include:

We tend to associate burning fat with endless exercise and painfully restrictive diets. However, getting a good amount of rest can also help get rid of the fat. Staying awake for too long can make us eat sugary foods to stay awake, give us tired and ineffective workouts, and it may even contribute to stress and inflammation, leading to poor workout recoveries.

One study found that not getting enough sleep decreased the proportion of fat weight loss by 55%. Another found that better sleep quality was linked to more weight and fat loss. Another study found a positive relationship between sleep duration and body fat loss.

The Mayo Clinic recommends adults get seven or more hours of sleep at night. Sleep needs can vary by individual, so adjust higher if seven doesn't quite feel like enough.

You have many different options when it comes to losing fat at home. You could try walking, running, high-intensity interval training or bodyweight training, all of which have studies to back up their fat loss capabilities.

You might also try adjusting your diet. Eat foods that are low in saturated fat and sugar and ones that can keep you full longer. Opt for high-protein or low-calorie foods like grilled chicken, beans, eggs or green tea. You can also try intermittent fasting.

Finally, make sure you are getting enough sleep. A good amount of sleep is also associated with fat loss.

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Janet Jackson weight gain can affect her upcoming music tour – The News International

Jan 28th, 2024
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You Lost the WeightNow What? – NewBeauty Magazine

Jan 28th, 2024
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Semaglutide medications show no signs of slowing down as a bonafide way to lose weight, but what happens once you reach optimal skinniness? Theres more to the effects of Ozempic than just weight loss, like changes to the skin, hollowing of the face, deflated breasts and butts, and potentially pronounced cellulite. Doctors are combining nonsurgical treatments and plastic surgery to restore harmony to the face and body so that everyone will only notice a slimmer body.

Losing weight with the help of medication is a godsend for many, but with rapid weight loss comes skin and volume changes that not everyone expects. Pasadena, CA plastic surgeon Lily Lee, MD explains that unlike bariatric surgery patients, who undergo psychological testing and therapy to ensure theyre ready for the effects of weight loss, semaglutide- assisted weight loss has a different buy-in. Sometimes, people who lose a lot of weight on semaglutide arent psychologically prepared for it, although theyre thrilled to lose it, she says.

Weight loss results in decreased fat, which affects skin quality, contour changes and facial volume. New York dermatologist Jody Levine, MD says weight loss can cause collagen and elastin fibers to become less resilient, which can result in sagging skin. Houston dermatologist Jennifer Segal, MD adds that fat reduction diminishes the underlying support, increasing bone and muscle visibility and creating shadows and contour changes.

Irvine, CA plastic surgeon Andrew Smith, MD is seeing plenty of patients experiencing facial volumetric shifts from Ozempic. Im also witnessing significant changes in breast volume increasing ptosis and skin-related changes around the abdomen, he shares. While many weight-loss patients are happy with how they look in clothing, Dr. Levine says she does see some who arent always as happy without it.

While preventing skin- and volume- related changes from weight loss is difficult, there are ways to slow the effects. Dr. Levine recommends establishing and maintaining a gradual, steady weight-loss plan to help the skin adapt more effectively. Adequate hydration, a balanced diet, and strength training exercises can support skin elasticity.

Even preemptive treatments negate some consequences. Patients started saying they wanted to lose 20 pounds but didnt want it to affect their face, says Dr. Lee. So, we have played around with Ultherapy and Morpheus8 to help tighten the face, but I always explain that the skin is a moving target when losing weight, she adds.

Ozempic face, which occurs when fat loss leaves the face looking saggy and aged, is the most talked about aesthetic effect of semaglutide. Patients using these medications for appropriate weight loss may be interested in cosmetic procedures to maintain a youthful appearance at their reduced body weight now that theyre feeling good and healthy, Dr. Segal shares.

While a facelift addresses loose, hanging skin, which can result from substantial weight loss, filler or microfat grafts are necessary to restore volume to flat, fat-deficient areas. Filler makes sense to use as the facial shape changes due to a loss of fat pads. Sometimes, a thinner face needs softening with appropriately placed volume, Dr. Smith explains. Relaxing certain muscles, like the glabella and forehead, with Botox makes for a nice combination approach, he adds.

The neck needs some fat to provide cushioning so the skin and underlying structures have something to cling to. Without adequate fat, the skin hangs and gives way to the dreaded turkey neck. Losing volume in the neck makes everything start to sag, which many patients feel ages them.

Dr. Lee says the knee-jerk reaction after slimming down is to get a necklift and, usually, a facelift since the two go hand-in-hand. Ive heard people say, I went on Ozempic to lose weight, and now I look old and skinny. When enough loose skin on the neck bothers someone, and they feel like a different person, surgical intervention, usually consisting of a necklift with a facelift with volume restoration, is required.

Ozempic butt is the newest terminology that doctors are starting to throw around. Dr. Segal explains that weight loss affects the butt like it does the face and other body parts. Loose skin and pronounced cellulite are typical, but a loss of volume, which causes the butt to look flat and shapeless, is also a common complaint. Plus, some patients notice a smaller backside after being on semaglutide medication.

Dr. Levine says various nonsurgical options, including Morpheus8 radio frequency microneedling and BodyTite, can improve the appearance of loose skin, but significant laxity can only be improved with surgical procedures. In some patients who lose a lot of fat, filler or fat transfer can revolumize the butt.

Since everyone holds weight differently in their breasts, some women see deflation following weight loss, whereas others see little or none. New York plastic surgeon Elie Levine, MD says breast augmentation restores a more youthful appearance to the breasts affected by a loss of volume and firmness.

Volume loss isnt the only issue. In some patients, the position of the breasts changes and the skin becomes loose. Usually, after weight loss, ptosis is common, so a mastopexy with or without augmentation is a good solution, Dr. Smith adds.

Women arent the only ones to experience changes to their chest post-Ozempic. Men can, too, but correcting the metamorphosis is tough. Men are not nearly as tolerant of scars that result from removing loose skin, so shrinking down the skin is a little trickier, says Dr. Lee. Traditionally, we would do liposuction and maybe a little skin resection, but nonsurgical options may suit them better since there arent any scars.

Like the breasts and butt, weight loss affects the stomach similarly. If the body naturally carries a large percentage of fat in the abdomen, the skin can drape over the stomach once fat is lost. Or, the upper abdominal skin becomes heavy and the extra skin covers the belly button, Dr. Lee adds.

Dr. Elie Levine says that the abdominal area is one of the more stubborn areas to repair to the desired appearance after weight loss. We can use Emsculpt NEO to address tone and fat and build muscle, and BodyTite to help tighten the skin, he says. For cases of excessive skin and severely loose abdominal muscles (usually a side effect of pregnancy more than weight loss), a tummy tuck creates a flatter-looking stomach sans hanging skin.

Losing weight in the arms is a big deal for many women, especially those who never felt comfortable wearing sleeveless tops. Since the skin on the arms doesnt always retract well, hanging skin can cause concern.

A brachioplasty is the best way to eliminate lax skin. However, the surgery can leave a long scar on the inside of the arm, which many are opposed to. To help reduce the scar, Dr. Lee says she often treats it with BodyTite, Renuvion or a heat-based treatment to get the skin to contract a little more.

Chicago plastic surgeon Michael Horn, MD performed an armlift on this 55-year-old patient to remove excess skin.

The knees can actually bear the brunt of weight lossthats because losing fat in the thighs can cause the skin on and above the knees to wrinkle. Its almost like theres a tub of fat that descends towards the knees, Dr. Lee says. Its a good area to treat with CoolSculpting and a skin tightener, but liposuction is the answer if that doesnt improve it enough. Liposuction can leave behind a small scar just above the knees that many people are not tolerant of.

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You Lost the WeightNow What? - NewBeauty Magazine

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